Science, hormesis and regulation

Human and Experimental Toxicology

Volumn 27, Issue 8, 2008, Pages 603-607

  Douglas, H ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Ethics; Explanatory power; Hormesis; Justice; Mixtures; Prediction; Regulatory agenda; Value of life

Indexed keywords

ENVIRONMENTAL EXPOSURE; ETHICS; HORMESIS; HUMAN; PRIORITY JOURNAL; PUBLIC HEALTH; REGULATORY MECHANISM; RISK ASSESSMENT; SHORT SURVEY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTION; HEALTH POLICY; HUMANS; RESEARCH; TOXINS, BIOLOGICAL; UNITED STATES;

EID: 57049113866     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/0960327108098493     Document Type: Short Survey

References (13)

1. Calabrese EF. Historical blunders: how toxicology got the dose-response relationship half right. Cell Mol Biol 2005 ; 51: 643 g-654.
2. Kitchin KT, Drane JW. A critique of the use of hormesis in risk assessment. Hum Exp Toxicol 2005 ; 24: 249 g-253.
3. Calabrese EF, Baldwin LA. Hormesis: the dose-response revolution. Annu Rev Pharmacol Toxicol 2003 ; 43: 175 g-197.
4. Rozman KK. Hormesis and risk assessment. Hum Exp Toxicol 2005 ; 24: 255 g-257.
5. 5 Popper K. Science: conjectures and refutations. London and New York: Routledge ; 2002. p. 43 g-78.
6. Calabrese EF, Baldwin LA. Hormesis: U-shaped dose responses and their centrality in toxicology. Trends Pharmacol Sci 2001 ; 22: 285 g-291.
7. Pickrell JA, Oehme FW. Examining the risk and benefits of replacing traditional dose-response with hormesis. Hum Exp Toxicol 2005 ; 24: 259 g-264.
8. Pickrell JA, Oehme FW. Examining the risks and benefits of considering both the traditional dose-response and hormesis in arriving at an acceptable exposure level. Hum Exp Toxicol 2006 ; 25: 23 g-27.
9. Weltje L, vom Saal FS, Oehlmann J. Reproductive stimulation by low doses of xenoestrogens contrasts with the view of hormesis as an adaptive response. Hum Exp Toxicol 2005 ; 24: 431 g-437.
10. Thayer KA, Melnick R, Burns K, Davis D, Huff J. Fundamental flaws of hormesis for public health decisions. Environ Health Perspect 2005 ; 113: 1271 g-1276.
11. Kaiser J. Sipping from a poisoned chalice. Science 2003 ; 302: 376 g-379.
12. 12 Fiorino D. Making environmental policy. Berkeley, CA: University of California Press ; 1995.
13. 13 National Research Council. Risk assessment in the federal government: managing the process. Washington DC: National Academy Press ; 1983.