Expression of vascular endothelial growth factor C is a prognostic indicator in esophageal cancer

Hepato-Gastroenterology

Volumn 55, Issue 86-87, 2008, Pages 1503-1508

  Okazawa, T ^a   Yoshida, T ^b   Shirai, Y ^a   Shiraishi, R ^a   Harada, T ^c   Sakaida, I ^a   Abe, T ^a   Oka, M ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c YAMAGUCHI UNIVERSITY HOSPITAL   (Japan)

Author keywords

Esophageal cancer; Prognosis; Vascular endothelial growth factor C

Indexed keywords

VASCULOTROPIN; VASCULOTROPIN C;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER INVASION; CANCER PATIENT; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; ESOPHAGUS CANCER; FEMALE; GENDER; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LYMPHANGIOGENESIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION;

AGED; AGED, 80 AND OVER; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PROGNOSIS; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

EID: 57049095938     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Veikkola T, Alitalo K: VEGFS, receptors and angiogenesis. Semin Cancer Biol 1999; 9:211-220.
2. Jeltsch M, Kaipainen A, Joukov V, Meng Y., Lakso M, Rauvala H, Swartz M, Fukumura D, Jain RK, Alitalo K: Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276(5317): 1423-1425. Erratum in: Science 1997; 277(5325):463.
3. Toi M, Hoshina S, Takayanagi T, Tominaga T: Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer. Jpn J Cancer Res 1994; 85:1045-1049.
4. Inoue K, Ozeki Y, Suganuma T, Sugiyama Y, Tanaka S: Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma. Cancer 1997; 79:206-213.
5. Maeda K, Chung Y, Ogawa Y, Takatsuka S, Kang SM, Ogawa M, Sawada T, Sowa M: Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer 1996; 77:855-863.
6. Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM: Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 1995; 55:3964-3968.
7. Kitadai Y, Amioka T, Haruma K, Tanaka S, Yoshihara M, Sumii K, Matsutani N, Yasui W, Chavama K: Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas. Int J Cancer 2001; 93(5):662-666.
8. Widner N, Semple Jp, Welch WR, Folkman J: Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 1991; 324:1-8
9. Kitagawa Y, Ueda M, Ando N, Ozawa S, Shimizu N, Kitajima M: Further evidence for prognostic significance of epidermal growth factor receptor gene amplification in patients with esophageal squamous cell carcinoma. Clin Cancer Res 1996; 2(5):909-914.
10. Takeuchi H, Ozawa S, Ando N, Shih CH, Koyanagi K, Ueda M, Kitajima M: Altered p16/MTS1/CDKN2 and cyclin D1/PRAD-1 gene expression is associated with the prognosis of squamous cell carcinoma of the esophagus. Clin Cancer Res 1997; 3(12):2229-2236.
11. Uchida S, Shimada Y, Watanabe G, Tanaka H, Shibagaki I, Miyahara T, Ishigami S, Imamura M: In oesophageal squamous cell carcinoma vascular endothelial growth factor is associated with p53 mutation, advanced stage and poor prognosis. Br J Cancer 1998; 77(10):1704-1709.
12. Kadowaki T, Shiozaki H, Inoue M, Tamura S, Oka H, Doki Y, Iihara K, Matsui S, Iwazawa T, Nagafuchi A, Tukita S, Mori T: E-cadherin and alpha-catenin expression in human esophageal cancer. Cancer Res 1994; 54(1):291-296.
13. Uchida S, Shimada Y, Watanabe G, Li ZG, Hong T, Miyake M, Imamura M: Motility-related protein (MRP-1/CD9) and KAI1/CD82 expression inversely correlate with lymph node metastasis in oesophageal squamous cell carcinoma. Br J Cancer 1999; 79(7-8):1168-1173.
14. Sakakibara T, Hibi K, Kodera Y, Ito K, Akiyama S, Nakao A: Plasminogen activator inhibitor-1 as a potential marker for the malignancy of esophageal squamous cell carcinoma. Clin Cancer Res 2004; 10(4):1375-1378.
15. Ding Y, Shimada Y, Maeda M, Kawahe A, Kaganoi J, Komoto I, Hashimoto Y, Miyake M, Hashida. H, Imamura M: Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma. Clin Cancer Res 2003; 9(9):3406-3412.
16. Miyazaki T, Kato H, Nakajima M, Sohda M, Fukai Y, Masuda N, Manda R, Fukuchi M, Tsukada K, Kuwano H: FAK overexpression is correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma. Br J Cancer 2003; 89:140-145.
17. Miyazaki T, Kato H, Fukuchi M, Nakajima M, Kuwano H: EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma. Int J Cancer 2003; 103:657-663.
18. Karpanen T, Egeblad M, Karkkainen MJ, Kubo H, Yla-Herttuala S, Jaattela M, Alitalo K: Vascular endothelial growth factor C promotes tumor lymphangio-genesis and intralymphatic tumor growth. Cancer Res 2001; 61(5):1786-1790.
19. Noguchi T, Takeno S, Shibata. T, Uchida Y, Yokoyama S, Muller W: VEGF-C expression correlates with histological differentiation and metastasis in squamous cell carcinoma of the esophagus. Oncol Rep 2002; 9(5):995-999.
20. Shih CH, Ozawa S, Ando N, Ueda M, Kitajima M: Vascular endothelial growth factor expression predicts outcome and lymph node metastasis in squamous cell carcinoma of the esophagus. Clin Cancer Res 2000; 6(3):1161-1168.
21. Kimura Y, Watanabe M, Ohga T, Saeki H, Kakeji Y, Baba H, Maehara Y: Vascular endothelial growth factor C expression correlates with lymphatic involvement and poor prognosis in patients with esophageal squamous cell carcinoma. Oncol Reports 2003; 10: 1747-1751.
22. Nakashima. T, Kondoh S, Kitoh H, Ozawa H, Okita S, Harada T, Shiraishi K, Ryozawa S, Okita K: Vascular endothelial growth factor-C expression in human gallbladder cancer and its relationship to lymph node metastasis. Int J Mol Med 2003; 11(1):33-39.
23. Fuji T, Sudo T, Sueyoshi S, Tanaka T, Hujita H, Shirouzu K, Ban S, Toyonaga A, Kato S, Yamana H: Clinicopathologic study of neovascularization and VEGF expression in superficial esophageal carcinoma. Int J Oncol 2002; 21:1181-1187.
24. Akagi K, Ikeda Y, Miyazaki M, Abe T, Kinoshita J, Machara Y, Sugimachi K: Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues. Br J Cancer 2000; 83(7):887-891.
25. Yonemura Y, Endo Y, Fujita H, Fushida. S, Ninomiya I, Bandon E, Taniguchi E, Miwa K, Ohoyama S, Sugiyama K, Sasaki T: Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer. Clin Cancer Res 1999; 5(7):1823-1829.
26. Kim HS, Kang HS, Messam CA, Min KW, Park CS: Comparative evaluation of angiogenesis in gastric adenocarcinoma by nestin and CD34. Appl Immunohistochem Mol Morphol 2002; 10(2):121-127.