Stimulus (polyphenol, IFN-γ, LPS)-dependent nitric oxide production and antileishmanial effects in RAW 264.7 macrophages

Phytochemistry

Volumn 69, Issue 18, 2008, Pages 3103-3110

  Kolodziej, Herbert ^a   Radtke, Oliver A ^a   Kiderlen, Albrecht F ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

Author keywords

Antileishmanial activity; Hydrolysable tannins; Immunomodulation; Leishmania; Macrophages; Nitric oxide; Polyphenols; Proanthocyanidins

Indexed keywords

ANTIPROTOZOAL AGENT; FLAVONOID; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHENOL DERIVATIVE; POLYPHENOLS;

ANIMAL; ARTICLE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; IMMUNOLOGY; LEISHMANIA; MACROPHAGE; METABOLISM; MOUSE; PARASITOLOGY;

ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; INTERFERON-GAMMA; LEISHMANIA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NITRIC OXIDE; PHENOLS;

EID: 56949104737     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2007.11.012     Document Type: Article

References (34)

1. Bogdan C., Röllinghoff M., and Diefenbach A. Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr. Opin. Immunol. 12 (2000) 64-76
2. Bredt D.S. Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free Radical Res. 31 (1999) 577-596
3. Chan M.M.-Y., Fong D., Ho C.-T., and Huang H.-I. Inhibition of inducible nitric oxide synthase gene expression and enzyme activity by epigallocatechin gallate, a natural product from green tea. Biochem. Pharmacol. 54 (1997) 1281-1286
4. Cheon B.S., Kim Y.H., Son K.S.S., Chang H.W., Kang S.S., and Kim H.P. Effects of prenylated flavonoids and biflavonoids on lipopolysaccharide-induced nitric oxide production from the mouse macrophage cell line RAW 264.7. Planta Med. 66 (2000) 596-600
5. Chiu F.-L., and Lin J.-K. HPLC analysis of naturally occurring methylated catechins, 3- and 4-methyl-epigallocatechin gallate, in various fresh tea leaves and commercial teas and their potent inhibitory effects on inducible nitric oxide synthase in macrophages. J. Agric. Food Chem. 53 (2005) 7035-7042
6. Cho K.-J., Yum C.-H., Yoon D.-Y., Cho Y.-S., Rimbach G., Packer L., and Chung A.-S. Effect of bioflavonoids extracted from the bark of Pinus maritima on proinflammatory cytokine interleukin-1 production in lipopolysaccharide-stimulated RAW 264.7. Toxicol. Appl. Pharmacol. 168 (2000) 64-71
7. Chung H.Y., Yokozawa T., Soung D.Y., Kye I.S., No J.K., and Baek B.S. Peroxynitrite-scavenging activity of green tea tannin. J. Agric. Food Chem. 46 (1998) 4484-4486
8. Ding A.H., Nathan C.F., and Stuehr D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141 (1988) 2407-2412
9. Feldman K.S. Recent progress in ellagitannin chemistry. Phytochemistry 66 (2005) 1984-2000
10. Habtemariam S. Natural inhibitors of tumour necrosis factor-α production, secretion and function. Planta Med. 66 (2000) 303-313
11. Haenen G.R.M.M., Paquay J.B.G., Korthouwer R.E.M., and Bast A. Peroxynitrite scavenging by flavonoids. Biochem. Biophys. Res. Commun. 236 (1997) 591-593
12. Ishii R., Horie M., Shibano T., Kitanaka S., and Amano F. Inhibitory effects of hydrolysable tannins from Melastoma dodecandrum Lour. on nitric oxide production by a murine macrophage-like cell line, RAW 24.7, activated with lipopolysaccharide and interferon-γ. Biol. Pharm. Bull. 22 (1999) 647-653
13. Kiderlen A.F., and Kaye P.M. A modified colorimetric assay of macrophage activation for intracellular cytotoxicity against Leishmania parasites. J. Immunol. Method 127 (1990) 11-18
14. Kiderlen A.F., Kayser O., Ferreira D., and Kolodziej H. Tannins and related compounds: killing of amastigotes of Leishmania donovani and release of nitric oxide and tumour necrosis factor α in macrophages in vitro. Z. Naturforsch. 56c (2001) 444-454
15. Kim H.K., Cheon B.S., Kim Y.H., Kim S.Y., and Kim H.P. Effects of naturally occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structure-activity relationships. Biochem. Pharmacol. 58 (1999) 759-765
16. Kolodziej H., Kayser O., Kiderlen A.F., Ito H., Hatano T., Yoshida T., and Foo L.Y. Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-α-release in the murine macrophage-like cell line RAW 264.7. Biol. Pharm. Bull. 24 (2001) 1016-1021
17. Kolodziej H., Kayser O., Kiderlen A.F., Ito H., Hatano T., Yoshida T., and Foo L.Y. Antileishmanial activity of hydrolysable tannins and their modulatory effects on nitric oxide and tumour necrosis factor-α-release in macrophages in vitro. Planta Med. 67 (2001) 825-832
18. Kolodziej H., and Kiderlen A.F. Antileishmanial activity and immune modulatory effects of tannins and related compounds on Leishmania parasitised RAW 264.7 cells. Phytochemistry 66 (2005) 2056-2071
19. Kolodziej H., Burmeister A., Trun W., Radtke O.A., Kiderlen A.F., Ito H., Hatano T., Yoshida T., and Foo L.Y. Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells. Bioorg. Med. Chem. 13 (2005) 6470-6476
20. Liew F.Y., Wei X.Q., and Proudfoot L. Cytokines and nitric oxide as effector molecules against parasitic infections. Trans. Roy. Soc. Lond. 352 (1997) 1311-1315
21. Lin Y.-L., and Lin J.-K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-κB. Mol. Pharmacol. 52 (1997) 465-472
22. Lowenstein C.J., Alley E.W., Raval P., Snowman A.M., Snyder S.H., Russell S.W., and Murphy W.J. Macrophage nitric oxide synthase: two upstream regions mediate induction by interferon-γ and lipopolysaccharide. Proc. Natl. Acad. Sci. USA 90 (1993) 9730-9734
23. Moncada S., Palmer R.M.J., and Higgs E.A. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43 (1991) 109-142
24. Nakagawa T., and Yokozawa T. Direct scavenging of nitric oxide and superoxide by green tea. Food Chem. Toxicol. 40 (2002) 1745-1750
25. Nakayama I., Kawahara Y., Tsuda T., Okuda M., and Yokoyama M. Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells. J. Biol. Chem. 269 (1994) 11628-11633
26. Nathan C.F., and Hibbs J.B. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr. Opin. Immunol. 3 (1991) 65-70
27. Okabe S., Suganuma M., Imayoshi Y., Taniguchi S., Yoshida T., and Fujikj H. New TNF-α releasing inhibitors, geraniin and corilagin, in leaves of Acer nikoense, Megusurino-ki. Biol. Pharm. Bull. 2001 (2001) 1145-1148
28. κB-dependent gene expression in RAW 264.7 macrophages. FEBS Lett. 465 (2000) 93-97
29. Radtke O.A., Kiderlen A.F., Kayser O., and Kolodziej H. Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid. Planta Med. 70 (2004) 924-928
30. r congenic mouse strains. Infect. Immun. 59 (1991) 3935-3944
31. Stevens J.F., Miranda C.L., Wolthers K.R., Schimerlik M., Denzer M.L., and Buhler D.R. Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species. J. Agric. Food Chem. 50 (2002) 3435-3443
32. Van Acker S.A.B.E., Tromp M.N.J.L., Haenen G.R.M.M., van der Vijgh W.J.F., and Bast A. Flavonoids as scavengers of nitric oxide radical. Biochem. Biophys. Commun. 214 (1995) 755-758
33. ®): scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW 264.7 macrophages. Free Radical Biol. Med. 24 (1998) 1120-1129
34. Yokozawa T., Chen C.P., and Tanaka T. Direct scavenging of nitric oxide by traditional crude drugs. Phytomedicine 6 (2000) 453-463