Mucosal immunization with purified ClpP could elicit protective efficacy against pneumococcal pneumonia and sepsis in mice

Microbes and Infection

Volumn 10, Issue 14-15, 2008, Pages 1536-1542

  Cao, Ju ^a,b   Chen, Tingmei ^a   Li, Dairong ^a   Wong, Chun K ^b   Chen, Dapeng ^a,b   Xu, Wenchun ^a   Zhang, Xuemei ^a   Lam, Christopher W K ^b   Yin, Yibing ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

ClpP; Mucosal immunization; Vaccine

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CHOLERA TOXIN; ENDOPEPTIDASE CLP; FREUND ADJUVANT; HEAT SHOCK PROTEIN; HYPERIMMUNE GLOBULIN; IMMUNOGLOBULIN G ANTIBODY; RECOMBINANT ENDOPEPTIDASE CLP; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; BACTERIAL COLONIZATION; BAGG ALBINO MOUSE; CBA MOUSE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; LOBAR PNEUMONIA; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; BLOOD; CHILD; CHILD, PRESCHOOL; COMPLEMENT SYSTEM PROTEINS; FEMALE; HUMANS; LUNG; MICE; MICE, INBRED BALB C; MICROBIAL VIABILITY; MUCOUS MEMBRANE; NEUTROPHILS; PNEUMOCOCCAL VACCINES; PNEUMONIA, PNEUMOCOCCAL; SEPSIS; SERINE ENDOPEPTIDASES; STREPTOCOCCUS PNEUMONIAE; SURVIVAL ANALYSIS;

MUS; STREPTOCOCCUS PNEUMONIAE;

EID: 56949095022     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2008.09.007     Document Type: Article

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