Tyrosine residues as redox cofactors in human hemoglobin: Implications for engineering nontoxic blood substitutes

Journal of Biological Chemistry

Volumn 283, Issue 45, 2008, Pages 30780-30787

  Reeder, Brandon J ^a   Grey, Marie ^b   Silaghi Dumitrescu, Radu Lucian ^c   Svistunenko, Dimitri A ^a   Bülow, Leif ^b   Cooper, Chris E ^a   Wilson, Michael T ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b LUND UNIVERSITY   (Sweden)

^c BABE BOLYAI UNIVERSITY   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD SUBSTITUTES; CHAINS; ELECTRON TRANSITIONS; FREE RADICAL REACTIONS; FREE RADICALS; HEMOGLOBIN; IRON; PORPHYRINS; PROTEINS; TOXICITY;

CRITICAL COMPONENT; ELECTRON TRANSFER; ELECTRON TRANSFER PATHWAYS; OXIDATIVE CONDITIONS; OXIDATIVE TOXICITY; PHENYLALANINE RESIDUES; TWO-ELECTRON TRANSFER; TYROSINE RESIDUES;

ELECTRON AFFINITY;

BLOOD SUBSTITUTE; HEMOGLOBIN; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN BETA CHAIN; MYOGLOBIN; PHENYLALANINE; TYROSINE;

ARTICLE; BINDING AFFINITY; BIOENGINEERING; CONCENTRATION (PARAMETERS); ELECTRON TRANSPORT; KINETICS; MUTATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ENGINEERING;

PHYSETERIDAE;

EID: 56949088820     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804709200     Document Type: Article

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