Erythropoietin improves oxidative stress following spinal cord trauma in rats

Injury

Volumn 39, Issue 12, 2008, Pages 1408-1413

  Yazihan, Nuray ^a   Uzuner, Kubilay ^b   Salman, Bulent ^c   Vural, Murat ^b   Koken, Tulay ^d   Arslantas, Ali ^b  

^a ANKARA UNIVERSITY   (Turkey)

^b ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

^c GAZI UNIVERSITY   (Turkey)

^d AFYON KOCATEPE UNIVERSITY   (Turkey)

Author keywords

Catalase; Erythropoietin (EPO); Experimental spinal cord trauma; Glutathione (GSH); Ketamine; Malonyldialdehyde (MDA); NMDA blocker; Oxidative stress; TNF alpha

Indexed keywords

CATALASE; GLUTATHIONE; KETAMINE; MALONALDEHYDE; RECOMBINANT ERYTHROPOIETIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; LAMINECTOMY; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPINAL CORD COMPRESSION; SPINAL CORD INJURY; TISSUE LEVEL; TREATMENT OUTCOME;

ANALGESICS; ANIMALS; ANTIOXIDANTS; ERYTHROPOIETIN; GLUTATHIONE; KETAMINE; LIPID PEROXIDATION; MALONDIALDEHYDE; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, WISTAR; SPINAL CORD INJURIES; SPINAL CORD ISCHEMIA;

EID: 56949085559     PISSN: 00201383     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.injury.2008.03.010     Document Type: Article

References (26)

1. Albers G.W., Goldberg M.P., and Choi D.W. N-methyl-D-aspartate antagonists: ready for clinical trial in brain ischemia?. Ann Neurol 25 4 (1989) 398-403
2. Beutler E., Robson M.J., and Buttenwieser E. The glutathione instability of drug sensitive red cells. J Lab Clin Med 49 (1957) 84
3. Beutler E. Red cell metabolism, a manual of biochemical methods (1973), Grune & Stratton, Inc., New York p. 76
4. Cerami A., Brines M.L., Ghezzi P., and Cerami C.J. Effects of Epoetin Alfa on the central nervous system. Semin Oncol 28 2 (8) (2001) 66-67
5. Chikuma M., Masuda S., Kobayashi T., et al. Tissue- specific regulation of erythropoietin production in the murine kidney, brain and uterus. Am J Physiol 279 6 (2000) E1242-E1248
6. Eid T., and Brines M. Recombinant human erythropoietin for neuroprotection: what is the evidence?. Clin Breast Cancer 3 Suppl. 3 (2002) S109-S115
7. Genc S., Akhisaroglu M., Kuralay F., and Genc K. Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro. Neurosci Lett 321 (2002) 73-76
8. Grasso G., Sfacteria A., Erbayraktar S., et al. Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative. J Neurosurg Spine 4 4 (2006) 310-318
9. Grasso G., Sfacteria A., Erbayraktar S., et al. Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietic erythropoietin derivative. Endocrinol Metab 279 4 (2000) E1242-E1248
10. Hanouz J.L., Zhu L., Persehaye E., et al. Ketamine preconditions isolated human right atrial myocardium: roles of adenosine triphosphate-sensitive potassium channels and adrenoceptors. Anesthesiology 102 6 (2005) 1190-1196
11. Hock N.H. Neuroprotective agents in acute ischemic stroke. J Cardiovasc Nurs 13 1 (1998) 17-25
12. Ii{dotless}zuka H., Yamamoto T., Iwasaki{dotless} Y., et al. Experimental spinal cord injury: quantitation of axonal damage by automated image analysis. J Neurosurg 64 (1986) 304-308
13. Kamencic H., Griebel R.W., Lyon A.W., et al. Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function. FASEB J 15 (2001) 243-250
14. Lezoualc'h F., Sagara Y., Holsboer F., and Behl C. High constitutive NF-kB activity mediates resistance to oxidative stress in neuronal cells. J Neurosci 18 (1998) 3224-3232
15. Lipton P. Ischemic cell death in brain neurons. Physiol Rev 79 4 (1999) 1431-1568
16. Lipton A.S., and Digicaylioglu M. Erythropoietin- mediated neuroprotection involves cross-talk between Jak2 and NF-κB signaling cascades. Nature 412 9 (2001) 641-647
17. Marti H.H., Wenger H.R., Rivas A.L., et al. Erythropoietin gene expression in human, monkey and murine brain. Eur J Neurosci 8 (1996) 666-676
18. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxidase in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 (1979) 351-358
19. Okutan O., Solaroglu I., Beskonakli E., and Taskin Y. Recombinant human erythropoietin decreases myeloperoxidase and caspase-3 activity and improves early functional results after spinal cord injury in rats. J Clin Neurosci 14 4 (2007) 364-368
20. Pedersen E.D., Waje-Andreassen U., Vedeler C.A., et al. Systemic complement activation following human acute ischaemic stroke. Clin Exp Immunol 137 1 (2004) 117-122
21. Schurr A. Neuroprotection against ischemic/hypoxic brain damage: blockers of ionotropic glutamate receptor and voltage sensitive calcium channels. Curr Drug Targets 5 7 (2004) 603-618
22. Sinor D.A., and Greenberg A.D. Erythropoietin protects cultured cortical neurons, but not astroglia, from hypoxia and AMPA toxicity. Neurosci Lett 290 (2000) 213-215
23. Siren A.L., Fratelli M., Brines M., et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. PNAS 27 98 (2001) 4044-4049 7
24. Sompol P., Xu Y., Ittarat W., et al. NF-kappaB-associated MnSOD induction protects against beta-amyloid-induced neuronal apoptosis. J Mol Neurosci 29 3 (2006) 279-288
25. Wang W., and Ballatori N. Endogenous glutathione conjugates: occurrence and biological functions. Pharm Rev 50 3 (1998) 335-355
26. Winterbourn C.C., Hawkins R.E., Brian M., and Correll R.W. The estimation of red cell superoxide dismutase activity. J Lab Clin Med 49 (1957) 84-95