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Volumn , Issue 41, 2008, Pages 25-29

Anti-ischemic cardioprotection with trimetazidine

Author keywords

Endothelium; Myocardial ischemia; Nitric oxide; Reperfusion damage; Trimetazidine

Indexed keywords

OXYGEN RADICAL; TRIMETAZIDINE;

EID: 56849112163     PISSN: 15660338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (7)

References (29)
  • 1
    • 0032776548 scopus 로고    scopus 로고
    • Reperfusion injury: Experimental evidence and clinical implications
    • Ambrosio G, Tritto I. Reperfusion injury: experimental evidence and clinical implications. Am Heart J. 1999;138:S69-S75.
    • (1999) Am Heart J , vol.138
    • Ambrosio, G.1    Tritto, I.2
  • 2
    • 0023192195 scopus 로고
    • Myocardial consequences of reperfusion
    • Becker IC, Ambrosio G. Myocardial consequences of reperfusion. Prog Cardiovasc Dis. 1987;30:23-41.
    • (1987) Prog Cardiovasc Dis , vol.30 , pp. 23-41
    • Becker, I.C.1    Ambrosio, G.2
  • 3
    • 0032869566 scopus 로고    scopus 로고
    • The role of neutrophils in myocardial ischemia-reperfusion injury
    • Jordan JE, Zhao ZQ, Vinten-Johansen J. The role of neutrophils in myocardial ischemia-reperfusion injury. Cardiovasc Res. 1999;43:860-878.
    • (1999) Cardiovasc Res , vol.43 , pp. 860-878
    • Jordan, J.E.1    Zhao, Z.Q.2    Vinten-Johansen, J.3
  • 4
    • 0036617862 scopus 로고    scopus 로고
    • Pathophysiology of ischemia-reperfusion injury: Experimental data
    • Di Napoli P, Taccardi AA, De Caterina R, Barsotti A. Pathophysiology of ischemia-reperfusion injury: experimental data. Ital Heart J. 2002;3 (suppl 4):24S-28S.
    • (2002) Ital Heart J , vol.3 , Issue.SUPPL. 4
    • Di Napoli, P.1    Taccardi, A.A.2    De Caterina, R.3    Barsotti, A.4
  • 5
    • 3142587121 scopus 로고    scopus 로고
    • Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction
    • Ruixing Y, Dezhai Y, Jiaquan L. Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction. J Med Invest. 2004;51:29-37.
    • (2004) J Med Invest , vol.51 , pp. 29-37
    • Ruixing, Y.1    Dezhai, Y.2    Jiaquan, L.3
  • 7
    • 0029956792 scopus 로고    scopus 로고
    • Apoptosis in ischemic and reperfused rat myocardium
    • Fliss H, Gattinger D. Apoptosis in ischemic and reperfused rat myocardium. Circ Res. 1996;79:949-956.
    • (1996) Circ Res , vol.79 , pp. 949-956
    • Fliss, H.1    Gattinger, D.2
  • 8
    • 10744222634 scopus 로고    scopus 로고
    • Left ventricular wall stress as a direct correlate of cardiomyocyte apoptosis in patients with severe dilated cardiomyopathy
    • Di Napoli P, Taccardi AA, Grilli A, et al. Left ventricular wall stress as a direct correlate of cardiomyocyte apoptosis in patients with severe dilated cardiomyopathy. Am Heart J. 2003;146:1105-1111.
    • (2003) Am Heart J , vol.146 , pp. 1105-1111
    • Di Napoli, P.1    Taccardi, A.A.2    Grilli, A.3
  • 9
    • 10644245294 scopus 로고    scopus 로고
    • Trimetazidine and cardioprotection during ischemia-reperfusion
    • Barsotti A, Di Napoli P. Trimetazidine and cardioprotection during ischemia-reperfusion. Ital Heart J. 2004;5:29S-36S.
    • (2004) Ital Heart J , vol.5
    • Barsotti, A.1    Di Napoli, P.2
  • 10
    • 0026454154 scopus 로고
    • The relative contribution of glucose and fatty acids to ATP production in hearts reperfused following ischemia
    • Lopaschuk GD, Saddik M. The relative contribution of glucose and fatty acids to ATP production in hearts reperfused following ischemia. Mol Cell Biochem. 1992;116:111-116.
    • (1992) Mol Cell Biochem , vol.116 , pp. 111-116
    • Lopaschuk, G.D.1    Saddik, M.2
  • 11
    • 0028085284 scopus 로고
    • Effects of glucose and fatty acids on myocardial ischemia and arrhythmias
    • Oliver MF, Opie LH. Effects of glucose and fatty acids on myocardial ischemia and arrhythmias. Lancet. 1994;343:155-158.
    • (1994) Lancet , vol.343 , pp. 155-158
    • Oliver, M.F.1    Opie, L.H.2
  • 12
    • 0032564373 scopus 로고    scopus 로고
    • Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiológicos Latinoamérica) Collaborative Group
    • Díaz R, Paolasso EA, Piegas LS, et al. Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiológicos Latinoamérica) Collaborative Group. Circulation. 1998;98:2227-2234.
    • (1998) Circulation , vol.98 , pp. 2227-2234
    • Díaz, R.1    Paolasso, E.A.2    Piegas, L.S.3
  • 13
    • 0033839320 scopus 로고    scopus 로고
    • Changes in intracellular sodium and pH during ischaemia-reperfusion are attenuated by trimetazidine. Comparison between low- and zero-flow ischaemia
    • El Banani H, Bernard M, Baetz D, et al. Changes in intracellular sodium and pH during ischaemia-reperfusion are attenuated by trimetazidine. Comparison between low- and zero-flow ischaemia. Cardiovasc Res. 2000;47:688-696.
    • (2000) Cardiovasc Res , vol.47 , pp. 688-696
    • El Banani, H.1    Bernard, M.2    Baetz, D.3
  • 14
    • 0036445726 scopus 로고    scopus 로고
    • Increase of adenosine plasma levels after oral trimetazidine: A pharmacological preconditioning?
    • Blardi P, de Lalla A, Volpi L, Auteri A, Di Perri T. Increase of adenosine plasma levels after oral trimetazidine: a pharmacological preconditioning? Pharmacol Res. 2002;45:69-72.
    • (2002) Pharmacol Res , vol.45 , pp. 69-72
    • Blardi, P.1    de Lalla, A.2    Volpi, L.3    Auteri, A.4    Di Perri, T.5
  • 15
    • 33645466318 scopus 로고    scopus 로고
    • Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure
    • Fragasso G, Perseghin G, De Cobelli F, et al. Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure. Eur Heart J. 2006;27:942-428.
    • (2006) Eur Heart J , vol.27 , pp. 942-428
    • Fragasso, G.1    Perseghin, G.2    De Cobelli, F.3
  • 16
    • 0032858431 scopus 로고    scopus 로고
    • Effects of trimetazidine administration before thrombolysis in patients with anterior myocardial infarction: Short-term and long-term results
    • Di Pasquale P, Lo Verso P, Bucca V, et al. Effects of trimetazidine administration before thrombolysis in patients with anterior myocardial infarction: short-term and long-term results. Cardiovasc Drugs Ther. 1999;13:423-428.
    • (1999) Cardiovasc Drugs Ther , vol.13 , pp. 423-428
    • Di Pasquale, P.1    Lo Verso, P.2    Bucca, V.3
  • 17
    • 33847051689 scopus 로고    scopus 로고
    • Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia reperfusion
    • Ruixing Y, Wenwu L, Al-Ghazali R. Trimetazidine inhibits cardiomyocyte apoptosis in a rabbit model of ischemia reperfusion. Transl Res. 2007;149:152-160.
    • (2007) Transl Res , vol.149 , pp. 152-160
    • Ruixing, Y.1    Wenwu, L.2    Al-Ghazali, R.3
  • 18
    • 27644492930 scopus 로고    scopus 로고
    • Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury
    • Argaud L, Gomez L, Gateau-Roesch O, et al. Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury. J Mol Cell Cardiol. 2005;39:893-899.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 893-899
    • Argaud, L.1    Gomez, L.2    Gateau-Roesch, O.3
  • 19
    • 0021961392 scopus 로고
    • Effects of trimetazidine on membrane damage reduced by oxygen free radicals in human red cells
    • Maridonneau-Parini I, Harpey C. Effects of trimetazidine on membrane damage reduced by oxygen free radicals in human red cells. Br J Clin Pharmacol. 1985;20:148-151.
    • (1985) Br J Clin Pharmacol , vol.20 , pp. 148-151
    • Maridonneau-Parini, I.1    Harpey, C.2
  • 21
    • 0027376285 scopus 로고
    • Trimetazidine inhibits neutrophil accumulation after myocardial ischaemia and reperfusion in rabbits
    • Williams FM, Tanda K, Kus M, Williams TJ. Trimetazidine inhibits neutrophil accumulation after myocardial ischaemia and reperfusion in rabbits. J Cardiovasc Pharmacol. 1993;22:828-833.
    • (1993) J Cardiovasc Pharmacol , vol.22 , pp. 828-833
    • Williams, F.M.1    Tanda, K.2    Kus, M.3    Williams, T.J.4
  • 23
    • 33644542154 scopus 로고    scopus 로고
    • Suppression of angioplasty-related inflammation by preprocedural treatment with trimetazidine
    • Kuralay F, Altekin E, Yazlar AS, Onvural B, Goldeli O. Suppression of angioplasty-related inflammation by preprocedural treatment with trimetazidine. Tohoku J Exp Med. 2006;208:203-212.
    • (2006) Tohoku J Exp Med , vol.208 , pp. 203-212
    • Kuralay, F.1    Altekin, E.2    Yazlar, A.S.3    Onvural, B.4    Goldeli, O.5
  • 24
    • 34249001974 scopus 로고    scopus 로고
    • Trimetazidine administration minimizes myocardial damage and improves left ventricular function after percutaneous coronary intervention
    • Labrou A, Giannoglou G, Zioutas D, Fragakis N, Katsaris G, Louridas G. Trimetazidine administration minimizes myocardial damage and improves left ventricular function after percutaneous coronary intervention. Am J Cardiovasc Drugs. 2007;7:143-150.
    • (2007) Am J Cardiovasc Drugs , vol.7 , pp. 143-150
    • Labrou, A.1    Giannoglou, G.2    Zioutas, D.3    Fragakis, N.4    Katsaris, G.5    Louridas, G.6
  • 25
    • 12744261465 scopus 로고    scopus 로고
    • Long term cardioprotective action of trimetazidine and potential effect on the inflammatory process in patients with ischaemic dilated cardiomyopathy
    • Di Napoli P, Taccardi AA, Barsotti A. Long term cardioprotective action of trimetazidine and potential effect on the inflammatory process in patients with ischaemic dilated cardiomyopathy. Heart. 2005;91:161-165.
    • (2005) Heart , vol.91 , pp. 161-165
    • Di Napoli, P.1    Taccardi, A.A.2    Barsotti, A.3
  • 26
    • 36349008130 scopus 로고    scopus 로고
    • Trimetazidine and reduction in mortality and hospitalization in patients with ischemic dilated cardiomyopathy: A post hoc analysis of the Villa Pini d'Abruzzo Trimetazidine Trial
    • Di Napoli P, Di Giovanni P, Gaeta MA, Taccardi AA, Barsotti A. Trimetazidine and reduction in mortality and hospitalization in patients with ischemic dilated cardiomyopathy: a post hoc analysis of the Villa Pini d'Abruzzo Trimetazidine Trial. J Cardiovasc Pharmacol. 2007;50:585-589.
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 585-589
    • Di Napoli, P.1    Di Giovanni, P.2    Gaeta, M.A.3    Taccardi, A.A.4    Barsotti, A.5
  • 27
    • 1542496389 scopus 로고    scopus 로고
    • Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy
    • Fragasso G, Piatti PM, Monti L, et al. Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy. Am Heart J. 2003;146:E18-E25.
    • (2003) Am Heart J , vol.146
    • Fragasso, G.1    Piatti, P.M.2    Monti, L.3
  • 28
    • 33846543123 scopus 로고    scopus 로고
    • Trimetazidine improves post-ischemic recovery by preserving endothelial nitric oxide synthase expression in isolated working rat hearts
    • Di Napoli P, Chierchia S, Taccardi AA, et al. Trimetazidine improves post-ischemic recovery by preserving endothelial nitric oxide synthase expression in isolated working rat hearts. Nitric Oxide. 2007;16:228-236.
    • (2007) Nitric Oxide , vol.16 , pp. 228-236
    • Di Napoli, P.1    Chierchia, S.2    Taccardi, A.A.3
  • 29
    • 34548363767 scopus 로고    scopus 로고
    • Trimetazidine improves endothelial dysfunction in chronic heart failure: An antioxidant effect
    • Belardinelli R, Solenghi M, Volpe L, Purcaro A. Trimetazidine improves endothelial dysfunction in chronic heart failure: an antioxidant effect. Eur Heart J. 2007;28:1102-1108.
    • (2007) Eur Heart J , vol.28 , pp. 1102-1108
    • Belardinelli, R.1    Solenghi, M.2    Volpe, L.3    Purcaro, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.