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Volumn , Issue 45, 2008, Pages 5963-5965

Fluorenes as new molecular scaffolds for carbon-carbon σ-bond cleavage reaction: Acylfluorenylation of arynes

Author keywords

[No Author keywords available]

Indexed keywords

ARYNE DERIVATIVE; FLUORENE DERIVATIVE; HALIDE; MOLECULAR SCAFFOLD; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; UNCLASSIFIED DRUG;

EID: 56749164601     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b814597k     Document Type: Article
Times cited : (58)

References (27)
  • 2
    • 11844273927 scopus 로고    scopus 로고
    • For recent examples on insertion reactions of alkynes into C-C σ-bonds, see:
    • C.-H. Jun Chem. Soc. Rev. 2004 33 610
    • (2004) Chem. Soc. Rev. , vol.33 , pp. 610
    • Jun, C.-H.1
  • 11
    • 31544449751 scopus 로고    scopus 로고
    • There has been no report on direct C-C bond insertion reactions of arynes using neutral C-CH compounds, except for refs. 3 and 4. For examples on the C-C bond insertion reactions of arynes using metal enolates, see:
    • H. Yoshida M. Watanabe J. Ohshita A. Kunai Chem. Lett. 2005 34 1538
    • (2005) Chem. Lett. , vol.34 , pp. 1538
    • Yoshida, H.1    Watanabe, M.2    Ohshita, J.3    Kunai, A.4
  • 26
    • 56749091232 scopus 로고    scopus 로고
    • A 15% yield of ethyl 2,7-bis(phenylethynyl)-9-phenylfluorene-9- carboxylate was also produced as a by-product via a formal C-H bond cleavage reaction
    • A 15% yield of ethyl 2,7-bis(phenylethynyl)-9-phenylfluorene-9- carboxylate was also produced as a by-product via a formal C-H bond cleavage reaction
  • 27
    • 56749166066 scopus 로고    scopus 로고
    • Inductive electron-withdrawing effect of a methoxy group in 3-methoxybenzyne also prefers nucleophilic attack at a meta position of the methoxy group Similar regioselectivities have been observed in the reaction of active methylene compounds. See ref. 4
    • Inductive electron-withdrawing effect of a methoxy group in 3-methoxybenzyne also prefers nucleophilic attack at a meta position of the methoxy group


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.