A review of CAM for procedural pain in infancy: Part I. Sucrose and non-nutritive sucking

Evidence-based Complementary and Alternative Medicine

Volumn 5, Issue 4, 2008, Pages 371-381

  Tsao, Jennie C I ^a   Evans, Subhadra ^a   Meldrum, Marcia ^b   Altman, Tamara ^a   Zeltzer, Lonnie K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Infant; Neonate; Nonnutritive sucking; Procedural pain; Sucrose

Indexed keywords

EMLA; GLUCOSE; PARACETAMOL; SUCROSE;

ALTERNATIVE MEDICINE; ANALGESIA; CIRCUMCISION; CLINICAL PROTOCOL; DATA BASE; DISTRESS SYNDROME; EVIDENCE BASED PRACTICE; HUMAN; INFANT; NERVE BLOCK; OUTCOME ASSESSMENT; PACIFIER; PAIN; PREMATURITY; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SUCKING; SURGICAL TECHNIQUE; VEIN PUNCTURE;

EID: 56749163586     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nem084     Document Type: Review

References (52)

1. Blass EM, Hoffmeyer LB. Sucrose as an analgesic for newborn infants. Pediatrics 1991;87:215-8.
2. Anand KJ, Hickey PR. Pain and its effects in the human neonate and fetus. N Engl J Med 1987;317:1321-9.
3. Kass FC, Holman JR. Oral glucose solution for analgesia in infant circumcision. J Fam Pract 2001;50:785-8.
4. Carbajal R, Lenclen R, Gajdos V, Jugie M, Paupe A. Crossover trial of analgesic efficacy of glucose and pacifier in very preterm neonates during subcutaneous injections. Pediatrics 2002;110:389-93.
5. Gunnar MR, Connors J, Isensee J, Wall L. Adrenocortical activity and behavioral distress in human newborns. Dev Psychobiol 1988;21:297-310.
6. Field T, Goldson E. Pacifying effects of nonnutritive sucking on term and preterm neonates during heelstick procedures. Pediatrics 1984;74:1012-5.
7. Tsao JCI, Zeltzer LK. Complementary and alternative medicine approaches for pediatric pain: a review of the state-of-the-science. Evid Based Complement Alternat Med 2005;2:149-59.
8. Stevens B, Yamada J, Ohlsson A. Sucrose for analgesia in newborn infants undergoing painful procedures. Cochrane Database Syst Rev 2004;CD001069.
9. Gibbins S, Stevens B, Hodnett E, Pinelli J, Ohlsson A, Darlington G. Efficacy and safety of sucrose for procedural pain relief in preterm and term neonates. Nurs Res 2002;51:375-82.
10. Johnston CC, Stremler R, Horton L, Friedman A. Effect of repeated doses of sucrose during heel stick procedure in preterm neonates. Biol Neonate 1999;75:160-6.
11. Stevens B, Johnston C, Franck L, Petryshen P, Jack A, Foster G. The efficacy of developmentally sensitive interventions and sucrose for relieving procedural pain in very low birth weight neonates. Nurs Res 1999;48:35-43.
12. Stevens B, Johnston C, Petryshen P, Taddio A. Premature infant pain profile: development and initial validation. Clin J Pain 1996;12:13-22.
13. Blass EM, Shah A. Pain-reducing properties of sucrose in human newborns. Chem Senses 1995;20:29-35.
14. Shiao SY, Chang YJ, Lannon H, Yarandi H. Meta-analysis of the effects of nonnutritive sucking on heart rate and peripheral oxygenation: research from the past 30 years. Issues Compr Pediatr Nurs 1997;20:11-24.
15. Campos RG. Soothing pain-elicited distress in infants with swaddling and pacifiers. Child Dev 1989;60:781-92.
16. Miller HD, Anderson GC. Nonnutritive sucking: effects on crying and heart rate in incubated infants requiring assisted mechanical ventilation. Nurs Res 1993;42:305-7.
17. Pinelli J, Symington A, Ciliska D. Nonnutritive sucking in high-risk infants: benign intervention or legitimate therapy? J Obstet Gynecol Neonatal Nurs 2002;31:582-91.
18. Corbo MG, Mansi G, Stagni A, Romano A, van den Heuvel J, Capasso L, et al. Nonnutritive sucking during heelstick procedures decreases behavioral distress in the newborn infant. Biol Neonate 2000;77:162-7.
19. Campos RG. Rocking and pacifiers: two comforting interventions for heelstick pain. Res Nurs Health 1994;17:321-31.
20. Blass EM. Behavioral and physiological consequences of suckling in rat and human newborns. Acta Paediatr Suppl 1994;397:71-6.
21. Blass EM, Watt LB. Suckling- and sucrose-induced analgesia in human newborns. Pain 1999;83:611-23.
22. Akman I, Ozek E, Bilgen H, Ozdogan T, Cebeci D. Sweet solutions and pacifiers for pain relief in newborn infants. J Pain 2002;3:199-202.
23. Carbajal R, Chauvet X, Couderc S, Olivier-Martin M. Randomised trial of analgesic effects of sucrose, glucose, and pacifiers in term neonates. Br Med J 1999;319:1393-7.
24. Stevens B, Yamada J, Beyene J, Gibbins S, Petryshen P, Stinson J, et al. Consistent management of repeated procedural pain with sucrose in preterm neonates: Is it effective and safe for repeated use over time? Clin J Pain 2005;21:543-8.
25. Gormally S, Barr RG, Wertheim L, Alkawaf R, Calinoiu N, Young SN. Contact and nutrient caregiving effects on newborn infant pain responses. Dev Med Child Neurol 2001;43:28-38.
26. Bellieni CV, Bagnoli F, Perrone S, Nenci A, Cordelli DM, Fusi M, et al. Effect of multisensory stimulation on analgesia in term neonates: a randomized controlled trial. Pediatr Res 2002;51:460-3.
27. Bellieni CV, Buonocore G, Nenci A, Franci N, Cordelli DM, Bagnoli F. Sensorial saturation: an effective analgesic tool for heel-prick in preterm infants: a prospective randomized trial. Biol Neonate 2001;80:15-8.
28. Gal P, Kissling GE, Young WO, Dunaway KK, Marsh VA, Jones SM, et al. Efficacy of sucrose to reduce pain in premature infants during eye examinations for retinopathy of prematurity. Ann Pharmacother 2005;39:1029-33.
29. Storm H, Fremming A. Food intake and oral sucrose in preterms prior to heel prick. Acta Paediatr 2002;91:555-60.
30. Boyer K, Johnston C, Walker CD, Filion F, Sherrard A. Does sucrose analgesia promote physiologic stability in preterm neonates? Biol Neonate 2004;85:26-31.
31. DiPietro JA, Hodgson DM, Costigan KA, Hilton SC, Johnson TR. Fetal neurobehavioral development. Child Dev 1996;67:2553-67.
32. Rush R, Rush S, Ighani F, Anderson B, Irwin M, Naqvi M. The effects of comfort care on the pain response in preterm infants undergoing screening for retinopathy of prematurity. Retina 2005;25:59-62.
33. Harrison D, Johnston L, Loughnan P. Oral sucrose for procedural pain in sick hospitalized infants: a randomized-controlled trial. J Paediatr Child Health 2003;39:591-7.
34. Akcam M, Ormeci AR. Oral hypertonic glucose spray: a practical alternative for analgesia in the newborn. Acta Paediatr 2004;93:1330-3.
35. Akcam M. Oral fructose solution as an analgesic in the newborn: A randomized, placebo-controlled and masked study. Pediatr Int 2004;46:459-62.
36. Bucher HU, Baumgartner R, Bucher N, Seiler M, Fauchere JC. Artificial sweetener reduces nociceptive reaction in term newborn infants. Early Hum Dev 2000;59:51-60.
37. Carbajal R, Veerapen S, Couderc S, Jugie M, Ville Y. Analgesic effect of breast feeding in term neonates: randomised controlled trial. Br Med J 2003;326:13.
38. Bilgen H, Ozek E, Cebeci D, Ors R. Comparison of sucrose, expressed breast milk, and breast-feeding on the neonatal response to heel prick. J Pain 2001;2:301-5.
39. Craig KD, Whitfield MF, Grunau RV, Linton J, Hadjistavropoulos HD. Pain in the preterm neonate: behavioural and physiological indices. Pain 1993;52:287-99.
40. Gradin M, Finnstrom O, Schollin J. Feeding and oral glucose-additive effects on pain reduction in newborns. Early Hum Dev 2004;77:57-65.
41. Abad F, Diaz-Gomez NM, Domenech E, Gonzalez D, Robayna M, Feria M. Oral sucrose compares favourably with lidocaine-prilocaine cream for pain relief during venepuncture in neonates. Acta Paediatr 2001;90:160-5.
42. Gradin M, Eriksson M, Holmqvist G, Holstein A, Schollin J. Pain reduction at venipuncture in newborns: oral glucose compared with local anesthetic cream. Pediatrics 2002;110:1053-7.
43. Gunnar MR, Fisch RO, Malone S. The effects of a pacifying stimulus on behavioral and adrenocortical responses to circumcision in the newborn. J Am Acad Child Psychiatry 1984;23:34-8.
44. Stang HJ, Snellman LW, Condon LM, Conroy MM, Liebo R, Brodersen L, et al. Beyond dorsal penile nerve block: a more humane circumcision. Pediatrics 1997;100:E3.
45. Brazelton TB. Neonatal Behavioral Assessment Scale. Philadelphia: Lippincott; 1973.
46. Herschel M, Khoshnood B, Ellman C, Maydew N, Mittendorf R. Neonatal circumcision. Randomized trial of a sucrose pacifier for pain control. Arch Pediatr Adolesc Med 1998;152:279-84.
47. Kaufman GE, Cimo S, Miller LW, Blass EM. An evaluation of the effects of sucrose on neonatal pain with 2 commonly used circumcision methods. Am J Obstet Gynecol 2002;186:564-8.
48. Razmus IS, Dalton ME, Wilson D. Pain management for newborn circumcision. Pediatr Nurs 2004;30:414-7, 427.
49. Merkel SI, Voepel-Lewis T, Shayevitz JR, Malviya S. The FLACC: a behavioral scale for scoring postoperative pain in young children. Pediatr Nurs 1997;23:293-7.
50. South MM, Strauss RA, South AP, Boggess JF, Thorp JM. The use of non-nutritive sucking to decrease the physiologic pain response during neonatal circumcision: a randomized controlled trial. Am J Obstet Gynecol 2005;193:537-42.
51. Gradin M. Effect of oral glucose on the heart rate of healthy newborns. Acta Paediatr 2005;94:324-8.
52. Taddio A, Nulman I, Koren BS, Stevens B, Koren G. A revised measure of acute pain in infants. J Pain Symptom Manage 1995;10:456-63.