A rat model for evaluating physiological responses to femoral shaft fracture reduction using a surgical robot

Journal of Orthopaedic Research

Volumn 26, Issue 12, 2008, Pages 1656-1659

  Oszwald, Markus ^a   Ruan, Zhiyong ^d   Westphal, Ralf ^b   O'Loughlin, Padhraig F ^c   Kendoff, Daniel ^c   Hufner, Tobias ^a   Wahl, Friedrich ^b   Krettek, Christian ^a   Gosling, Thomas ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

^d People's Hospital   (China)

Author keywords

External fixator; Femoral fracture reduction; Physiological responses; Rat model; Surgical robot

Indexed keywords

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEASIBILITY STUDY; FEMUR OSTEOTOMY; FEMUR SHAFT FRACTURE; FRACTURE FIXATION; FRACTURE REDUCTION; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; RAT; ROBOTICS; SURGICAL TECHNIQUE;

ANIMALS; FEMORAL FRACTURES; MODELS, ANIMAL; ORTHOPEDIC PROCEDURES; OSTEOTOMY; RATS; ROBOTICS;

EID: 56749163498     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20698     Document Type: Article

References (11)

1. Bunn JR, Canning J, Burke G, et al. 2004. Production of consistent crush lesions in murine quadriceps muscle - a biomechanical, histomorphological and immunohistochemical study. J Orthop Res 22:1336-1344.
2. Cipolle MD, Pasquale MD, Shearer J, et al. 1994. Blunt injury augments interleukin-6 but not tumor necrosis factor in isolated, perfused rat hindlimbs. J Trauma 37:91-98; discussion 98-99.
3. Gosling T, Westphal R, Hufner T, et al. 2005. Robot-assisted fracture reduction: a preliminary study in the femur shaft. Med Biol Eng Comput 43:115-120.
4. Harwood PJ, Giannoudis PV, van Griensven M, et al. 2005. Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients. J Trauma 58:446-452; discussion 452-454.
5. Levy RM, Prince JM, Yang R, et al. 2006. Systemic inflammation and remote organ damage following bilateral femur fracture requires toll-like receptor 4. Am J Physiol Regul Integr Comp Physiol 291:R970-976.
6. Pape HC, Hildebrand F, Pertschy S, et al. 2002. Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery. J Trauma 53:452-461; discussion 461-462.
7. Pape HC, Schmidt RE, Rice J, et al. 2000. Biochemical changes after trauma and skeletal surgery of the lower extremity: quantification of the operative burden. Crit Care Med 28:3441-3448.
8. Pasquale MD, Cipolle MD, Monaco J, et al. 1996. Early inflammatory response correlates with the severity of injury. Crit Care Med 24:1238-1242.
9. Wang W, Smail N, Wang P, et al. 1998. Increased gut permeability after hemorrhage is associated with upregulation of local and systemic IL-6. J Surg Res 79:39-46.
10. Weil YA, Liebergall M, Mosheiff R, et al. 2007. Long bone fracture reduction using a fluoroscopy-based navigation system: A feasibility and accuracy study. Comput Aided Surg 12:295-302.
11. Roumen RM, Redl H, Schlag G, et al. 1995. Inflammatory mediators in relation to the development of multiple organ failure in patients after severe blunt trauma. Crit Care Med 23:474-480.