The effect of chronic oral feeding of Apium graveolens on learning and memory in diabetic rats

Journal of Medicinal Plants

Volumn 7, Issue 27, 2008, Pages 98-105

  Roghani, M ^a   Baluchnejadmojarad, T ^b   Ramazani, M ^a  

^a SHAHED UNIVERSITY   (Iran)

^b IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Apium graveolens; Diabetes mellitus; Learning; Memory; Rat; Streptozotocin

Indexed keywords

APIUM GRAVOLENS EXTRACT; LIPID; PLANT EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APIUM GRAVOLENS; ARTICLE; CONTROLLED STUDY; HYPERLIPIDEMIA; INSULIN DEPENDENT DIABETES MELLITUS; LEARNING; LIPID BLOOD LEVEL; LIPID PEROXIDATION; MAZE TEST; MEDICINAL PLANT; MEMORY; NONHUMAN; PASSIVE AVOIDANCE; RAT; SPATIAL MEMORY; WEIGHT; WISTAR ALBINO GLAXO RAT;

ANIMALIA; APIUM GRAVEOLENS; RATTUS;

EID: 56749161471     PISSN: 2717204X     EISSN: 27172058     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Tripathi BK, Srivastava AK. Diabetes mellitus: complications and therapeutics. Med. Sci. Monit. 2006; 12: 130-47.
2. Wandell PE. Quality of life of patients with diabetes mellitus. An overview of research in primary health care in the Nordic countries. Scand. J. Prim. Health Care 2005; 23: 68-74.
3. Galer BS, Gianas A, Jensen MP: Painful diabetic polyneuropathy: epidemiology, pain description, and quality of life. Diabetes Res. Clin. Pract. 2000; 47: 123-8.
4. Jackson-Guilford J, Leander JD, Nisenbaum LK. The effect of streptozotocin-induced diabetes on cell proliferation in the rat dentate gyrus. Neurosci. Lett. 2000; 293: 91-4.
5. Biessels GJ, Smale S, Duis SE, Kamal A, Gispen WH. The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. J. Neurol. Sci. 2001; 182: 99-106.
6. Parihar MS, Chaudhary M, Shetty R, Hemnani T. Susceptibility of hippocampus and cerebral cortex to oxidative damage in streptozotocin treated mice: prevention by extracts of Withania somnifera and Aloe vera. J Clin. Neurosci. 2004; 11:397-402.
7. Reagan LP, McEwen BS. Diabetes, but not stress, reduces neuronal nitric oxide synthase expression in rat hippocampus: implications for hippocampal synaptic plasticity. Neuroreport 2002; 13: 1801-4.
8. Baydas G, Nedzvetskii VS, Nerush PA, Kirichenko SV, Yoldas T. Altered expression of NCAM in hippocampus and cortex may underlie memory and learning deficits in rats with streptozotocin-induced diabetes mellitus. Life Sci. 2003; 73: 1907-16.
9. Scartezzini P, Speroni E. Review on some plants of Indian traditional medicine with antioxidant activity. J. Ethnopharmacol. 2000; 71: 23-43.
10. Ninfali P, Bacchiocca M. Polyphenols and antioxidant capacity of vegetables under fresh and frozen conditions. J. Agric Food Chem. 2003; 51: 2222-6.
11. Momin RA, Nair MG. Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. Phytomedicine 2002; 9: 312-8.
12. Ahmed B, Alam T, Varshney M, Khan SA. Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family. J. Ethnopharmacol. 2002; 79: 313-6.
13. Atta AH, Alkofahi A. Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts. J. Ethnopharmacol. 1998; 60: 117-24.
14. Tsi D, Das NP, Tan BK. Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet. Planta Med. 1995; 61: 18-21.
15. Rahimi R, Nikfar S, Larijani B, Abdollahi M. A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother. 2005; 59: 365-73.
16. Kowluru RA, Chan P. Oxidative Stress and Diabetic Retinopathy. Exp. Diabetes Res. 2007; 1: 43603.
17. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Evaluation of traditional plant treatments for diabetes: studies in streptozotocin diabetic mice, Acta Diabetologica Latina, 1989; 26: 51-8.
18. Lupien SB, Bluhm EJ, Ishii DN. Systemic insulin-like growth factor-I administration prevents cognitive impairment in diabetic rats, and brain IGF regulates learning/memory in normal adult rats. J. Neurosci. Res. 2003; 74: 512-23.
19. Biessels GJ, ter Laak MP, Kamal A, Gispen WH. Effects of the Ca2+ antagonist nimodipine on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. Brain Res. 2005; 1035: 86-93.
20. Nitta A, Murai R, Suzuki N, Ito H, Nomoto H, Katoh G, Furukawa Y, et al. Diabetic neuropathies in brain are induced by deficiency of BDNF. Neurotoxicol Teratol 2002; 24: 695-701.
21. Mayer G, Nitsch R, Hoyer S. Effects of changes in peripheral and cerebral glucose metabolism on locomotor activity, learning and memory in adult male rats. Brain Res. 1990; 532: 95-100.
22. Artola A, Kamal A, Ramakers GM, Biessels GJ, Gispen WH. Diabetes mellitus concomitantly facilitates the induction of long-term depression and inhibits that of long-term potentiation in hippocampus. Eur. J. Neurosci. 2005; 22: 169-78.
23. Sima AA, Li ZG. The effect of C-peptide on cognitive dysfunction and hippocampal apoptosis in type 1 diabetic rats. Diabetes 2005; 54: 1497-505.
24. Reagan LP, McEwen BS. Diabetes, but not stress, reduces neuronal nitric oxide synthase expression in rat hippocampus: implications for hippocampal synaptic plasticity. Neuroreport 2002; 13: 1801-4.
25. Wioeniewski K, Fedosiewicz-wasiluk M, Holy ZZ, Car H, Grzeda E. Influence of NMDA, a potent agonist of glutamate receptors, on behavioral activity in 4-week streptozotocin-induced diabetic rats. Pol. J. Pharmacol. 2003; 55: 345-51.
26. Gebhardt Y, Witte S, Forkmann G, Lukacin R, Matern U, Martens S. Molecular evolution of flavonoid dioxygenases in the family Apiaceae. Phytochemistry 2005; 66: 1273-84.
27. Momin RA, Nair MG. Antioxidant, cyclooxygenase and topoisomerase inhibitory compounds from Apium graveolens Linn. seeds. Phytomed. 2002; 9: 312-8.