Responses of human motoneurons to high-frequency stimulation of Ia afferents

Muscle and Nerve

Volumn 38, Issue 6, 2008, Pages 1604-1615

  Bawa, Parveen ^a   Chalmers, Gordon ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b WESTERN WASHINGTON UNIVERSITY   (United States)

Author keywords

EPSP; H reflex; High frequency stimulus; Motor unit; Spindle afferents

Indexed keywords

ADULT; AFFERENT NERVE GROUP 1; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAPHY; EVOKED MUSCLE RESPONSE; FEMALE; FLEXOR CARPI RADIALIS; HISTOGRAM; HUMAN; HUMAN EXPERIMENT; MALE; MONOSYNAPTIC PATHWAY; MOTOR UNIT; NERVE CELL STIMULATION; NORMAL HUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; SOLEUS MUSCLE; SPINAL CORD MOTONEURON;

ADULT; ANIMALS; CATS; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR NEURONS; MUSCLE FIBERS, SKELETAL; NEURONS, AFFERENT; YOUNG ADULT;

EID: 56749158082     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.21184     Document Type: Article

References (39)

1. Bartley K, Woodforth IJ, Stephen JP, Burke D. Corticospinal volleys and compound muscle action potentials produced by repetitive transcranial stimulation during spinal surgery. Clin Neurophysiol 2002;113:78-90.
2. Bawa P, Calancie B. Repetitive doublets in human flexor carpi radialis muscle. J Physiol (Lond) 1983;339:123-132.
3. Bawa P, Calancie B. Rate-coding of spinal motoneurons with high-frequency magnetic stimulation of human motor cortex. Can J Physiol Pharm 2004;82:740 -748.
4. Bawa P, Chalmers GR. Transmission of high frequency bursts along the monosynaptic reflex arc in the upper and lower limb muscles in humans. Atlanta, GA: Abstracts of Society of Neuroscience Meeting; 2006.
5. Brock LG, Eccles JC, Rall W. Experimental investigations on the afferent fibres in muscle nerves. Proc Roy Soc London B 1951;138:453-474.
6. Buchthal F, Rosenfalck A. Evoked action potentials and conduction velocity in human sensory nerves. Brain Res 1966;3:1-122.
7. Burke D, Gandevia SC, McKeon B. The afferent volleys responsible for spinal proprioceptive reflexes in man. J Physiol (Lond) 1983;339:535-552.
8. Burke D, Kiernan MC, Bostock H. Excitability of human axons. Clin Neurophysiol 2001;112:1575-1585.
9. Burke D, Schiller HH. Discharge pattern of single motor units in the tonic vibration reflex of human triceps surae. J Neurol Neurosurg Psychiatry 1976;39:729-441.
10. Burke RE, Rudomin P, Zajac FE. Catch property of single mammalian motor units. Science 1970;168:122-124.
11. Calvin WH. Generation of spike trains in CNS neurons. Brain Res 1975;84:1-22.
12. Collins WF, Honig MG, Mendell LM. Heterogeneity of group Ia synapses on homonymous α-motoneurons as revealed by high-frequency stimulation of Ia afferent fibers. J Neurophysiol 1984;52:980-993.
13. Cope TC, Fetz EE, Matsumura M. Cross correlation assessment of synaptic strength of single Ia fibre connections with triceps surae motoneurones in cats. J Physiol 1987;390:161-188.
14. Curtis DR, Eccles JC. Synaptic action during and after repetitive stimulation. J Physiol (Lond) 1960;150:374-398.
15. Deletis V, Isgum V, Ammassian V. Neurophysiological mechanisms underlying motor evoked potentials in anesthetized humans. Part 2. Relationship between epidurally and muscle recorded MEPs in man. Clin Neurophysiol 2001;112:445-452.
16. Eccles JC, Rall W. Repetitive monosynaptic activation of motoneurons. Proc R Soc London B 1951;183:475-498.
17. Eccles JC, Rall W. Effects induced in a monosynaptic reflex path by its activation. J Neurophysiol 1951;14:354-376.
18. Fetz EE, Gustafsson B. Relation between shapes of post-synaptic potentials and changes in firing probability of cat motoneurones. J Physiol (Lond) 1983;341:387-410.
19. Finkelman AS, Redman SJ. The synaptic current evoked in cat spinal motoneurones by impulses in single group Ia axons. J Physiol (Lond) 1983;342:615-632.
20. Honig MG, Collins WF III, Mendell LM. Alpha-motoneuron EPSPs exhibit different frequent sensitivities to single 1aafferent fiber stimulation. J Neurophysiol 1983;49:886-901.
21. Hultborn H, Illert M, Nielsen J, Paul A, Ballegaard M, Wiese H. On the mechanism of the post-activation depression of the H-reflex in human subjects. Exp Brain Res 1996;108:450-462.
22. Jackson A, Baker SN, Fetz EE. Tests for presynaptic modulation of corticospinal terminals from peripheral afferents and pyramidal tract in the macaque. J Physiol 2006;573:107-120
23. Jones KE, Bawa P. Effect of firing rate on the excitability of human motoneurons. Can J Physiol Pharm 1995;73:1224-1234.
24. Jones KE, Bawa P. A comparison of human motoneuron data to simulated data using cat motoneuron models. J Physiol (Paris) 1999;93:43-59.
25. Jones KE, Calancie B, Hall A, Bawa P. Comparison of peripheral Ia and corticomotoneuronal composite EPSPs in human motoneurons. EEG Clin Neurophysiol 1996;101:431-437.
26. Koerber HR, Mendell LM. Modulation of synaptic transmission at Ia-afferent connections on motoneurons during high frequency afferent stimulation: dependence on motor tasks. J Neurophysiol 1991;65:1313-1320.
27. Kuno M. Mechanism of facilitation and depression of the excitatory synaptic potential in spinal motoneurons. J Physiol (Lond) 1964;175:100-112.
28. Kuno M, Miyahara JT. Analysis of synaptic efficacy in spinal motoneurones from 'quantum' aspects. J Physiol (Lond) 1969;201:479-493.
29. Loeb GE, Duysens J. Activity patterns in individual hind limb primary and secondary muscle spindle afferents during normal movements in unrestrained cats. J. Neurophysiol 1979;42:420-440.
30. Novak K, Bueno de Camargo A, Neuwirth M, Kothbauer K, Amassian VE, Deletis V. The refractory period of fast conducting corticospinal tract axons in man and its implications for intraoperative monitoring of motor evoked potentials. Clin Neurophysiol 2004;115:1931-1941.
31. Phillips CG, Porter R. The pyramidal projection to motoneurones of some muscle groups of the baboon's forelimb. In: Eccles JC, Schadé JP, ed. Physiology of spinal neurons. Progress in brain research. Vol. 12. New York: Elsevier; 1964. p 222-245.
32. Porter R, Lemon RN. Corticospinal function and voluntary movement. Oxford, UK: Oxford University Press; 1993.
33. Prochazka A, Westerman RA, Ziccone SP. Discharge of single hindlimb afferents in the freely moving cat. J Neurophysiol 1976;39:1090-1104.
34. Prochazka A, Westerman RA, Ziccone SP. Ia afferent activity during a variety of voluntary movements in the cat. J Physiol (Lond) 1977;268:423-448.
35. Rossi-Durand C, Jones KE, Adams S, Bawa P. Comparison of H-reflexes in upper and lower limb muscles. Exp Brain Res 1999;126:117-127.
36. Shapovalov AI. Neuronal organization and synaptic mechanisms of supraspinal motor control in vertebrates. Rev Physiol Biochem Pharmacol 1975;72:1-54.
37. Stevens P, Bawa P. Refractoriness of sural nerve in humans. Can J Physiol Pharm 2008;86:600-605.
38. Stein RB, Parmiggiani F. Nonlinear summation of contractions in cat muscles. J Gen Physiol 1981;78:277-293.
39. Zajac FE, Young JL. Properties of stimulus trains producing maximum tension-time area per pulse from single motor units in medial gastrocnemius muscle of the cat. J Neurophysiol 1980;43:1206-1220.