Rate-coding of spinal motoneurons with high-frequency magnetic stimulation of human motor cortex

Canadian Journal of Physiology and Pharmacology

Volumn 82, Issue 8-9, 2004, Pages 740-748

  Bawa, Parveen ^a   Calancie, Blair ^b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

Corticomotoneuron; High frequency stimulation; Human; Peri stimulus time histogram; Rate coding; Repetitive transcranial magnetic stimulation; Single motor unit

Indexed keywords

ADULT; COMPARATIVE STUDY; CONFERENCE PAPER; ELECTROMYOGRAPHY; EXTENSOR MUSCLE; FEMALE; FLEXOR MUSCLE; HUMAN; HUMAN EXPERIMENT; MAGNETIC STIMULATION; MALE; MOTOR CONTROL; MOTOR CORTEX; MOTOR UNIT POTENTIAL; MUSCLE CONTRACTION; NEUROMODULATION; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; TIBIALIS ANTERIOR MUSCLE;

ACTION POTENTIALS; ADULT; ELECTROMAGNETIC FIELDS; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR CORTEX; MOTOR NEURONS;

EID: 11244299721     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y04-069     Document Type: Conference Paper

References (36)

1. Bartley, K., Woodforth, I.J., Stephen, J.P., and Burke, D. 2002. Corticospinal volleys and compound muscle action potentials produced by repetitive transcranial stimulation during spinal surgery. Clin. Neurophysiol. 113: 78-90.
2. Bawa, P., and Calancie, B. 1983. Repetitive doublets in human flexor carpi radialis muscle. J. Physiol. 339: 123-132.
3. Bawa, P., and Lemon, R.N. 1993. Recruitment of motor units in response to transcranial magnetic stimulation in man. J. Physiol. 471: 445-464.
4. Bawa, P., Chalmers, G.R., Stewart, H., and Eisen, A.A. 2002. Responses of ankle extensor and flexor motoneurons to transcranial magnetic stimulation. J. Neurophysiol. 88: 124-132.
5. Burke, R.E. 1981. Motor units: Anatomy, physiology, and functional organization. In Handbook of physiology. The nervous system. Edited by V.B. Brooks. American Physiological Society, Bethesda, Md. pp. 345-442.
6. Burke, R.E., Rudomin, P., and Zajac, F.E.I.I. 1976. The effect of activation history on tension production by individual muscle units. Brain Res. 109: 515-529.
7. Calancie, B., Nordin, M., Wallin, R., and Hagbarth, K.E. 1987. Motor-unit responses in human wrist flexor and extensor muscles to transcranial cortical stimuli. J. Neurophysiol. 58: 1168-1185.
8. Calancie, B., Harris, W., Broton, J.G., Alexeeva, N., and Green, B.A. 1998. "Threshold-level" multipulse transcranial electrical stimulation of motor cortex for intraoperative monitoring of spinal motor tracts: description of method and comparison to somatosensory evoked potential monitoring. J. Neurosurg. 88: 457-470.
9. Daskalakis, Z.J., Christensen, B.K., Fitzgerald, P.B., Roshan, L., and Chen, R. 2002. The mechanisms of interhemispheric inhibition in the human motor cortex. J. Physiol. 543: 317-326.
10. Day, B.L., Rothwell, J.C., Thompson, P.D., Dick, J.P.R., Cowan, J.M.A., Berardelli, A., and Marsden, C.D. 1987. Motor cortex stimulation in intact man. 2. Multiple descending volleys. Brain, 110: 1191-1209.
11. Deletis, V., Isgum, V., and Amassian, V.E. 2001. Neurophysiological mechanisms underlying motor evoked potentials in anesthetized humans. Part 1. Recovery time of corticospinal tract direct waves elicited by pairs of transcranial electrical stimuli. Clin. Neurophysiol. 112: 438-444.
12. Edgley, S.A., Eyre, J.A., Lemon, R.N., and Miller, S. 1997. Comparison of activation of corticospinal neurons and spinal motor neurons by magnetic and electrical transcranial stimulation in the lumbosacral cord of the anaesthetized monkey. Brain, 120: 839-853.
13. Evarts, EV. 1981. Role of motor cortex in voluntary movements in primates. In Handbook of physiology. The nervous system. Edited by V.B. Brooks. American Pysiological Society, Bethesda, Md. pp. 1083-1120.
14. Fetz, E.E., and Cheney, P.D. 1980. Postspike facilitation of forelimb muscle activity by primate corticomotoneuronal cells. J. Neurophysiol. 44: 751-772.
15. Fisher, R.J., Nakamura, Y., Bestmann, S., Rothwell, J.C., and Bostock, H. 2002. Two phases of intracortical inhibition revealed by transcranial magnetic threshold tracking. Exp. Brain Res. 143: 240-248.
16. Gurfinkel, V.S., and Levik, Y.S. 1974. Effects of a doublet or omission and their connection with the dynamics of the active state of human muscles. Biofizika, 19: 925-931.
17. Hanajima, R., Ugawa, Y., Terao, Y., Enomoto, H., Shiio, Y., Mochizuki, H., Furubayashi, T., Uesugi, H., Iwata, N.K., and Kanazawa, I. 2002. Mechanisms of intracortical I-wave facilitation elicited with paired- pulse magnetic stimulation in humans. J. Physiol. 538: 253-261.
18. Henneman, E, and Mendell, LM. 1981. Functional organization of motoneuron pool and its inputs. In Handbook of physiology. The nervous system. Edited by V.B. Brooks. American Physiological Society, Bethesda, Md. pp. 423-507.
19. Ilic, T.V., Meintzschel, F., Cleff, U., Ruge, D., Kessler, K.R., and Ziemann, U. 2002. Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensity. J. Physiol. 545: 153-167.
20. Jones, K.E., and Bawa, P. 1997. Computer simulation of the responses of human motoneurons to composite IA EPSPS: Effects of background firing rate. J. Neurophysiol. 77: 405-420.
21. Keel, J.C., Smith, M.J., and Wassermann, E.M. 2001. A safety screening questionnaire for transcranial magnetic stimulation. Clin. Neurophysiol. 112: 720.
22. Lemon, R.N. 1993. Cortical control of the primate hand. The 1992 G.L. Brown Prize Lecture. Exp. Physiol. 78: 263-301.
23. Lemon, R.N., Hanby, J.A., and Porter, R. 1976. Relationship between the activity of precentral neurones during active and passive movements in conscious monkeys. Proc. R. Soc. Lond. B Biol. Sci. 194: 341-373.
24. Maertens de Noordhout, A., Rapisarda, G., Bogacz, D., Gerard, P., De Pasqua, V., Pennisi, G., and Delwaide, P.J. 1999. Corticomotoneuronal synaptic connections in normal man. An electrophysiological study. Brain, 122: 1327-1340.
25. Milner-Brown, H.S., Stein, R.B., and Yemm, R. 1973a. Changes in firing rate of human motor units during linearly changing voluntary contractions. J. Physiol. 230: 371-390.
26. Milner-Brown, H.S., Stein, R.B., and Yemm, R. 1973b. The contractile properties of human motor units during voluntary isometric contractions. J. Physiol. 228: 285-306.
27. Milner-Brown, H.S., Stein, R.B., and Yemm, R. 1973c. The orderly recruitment of human motor units during voluntary isometric contractions. J. Physiol. 230: 359-370.
28. Palmer, E., and Ashby, P. 1992. Corticospinal projections to upper limb motoneurones in humans. J. Physiol. 448: 397-412.
29. Parmiggiani, F., and Stein, R.B. 1981. Nonlinear summation of contractions in cat muscles II. Later facilitation and stiffness changes. J. Gen. Physiol. 78: 295-311.
30. Patton, H.D., and Amassian, V.E. 1954. Single and multiple unit analysis of cortical stage of pyramidal tract activation. J. Neurophysiol. 17: 345-363.
31. Pechstein, U., Cedzich, C., Nadstawek, J., and Schramm, J. 1996. Transcranial high-frequency repetitive electrical stimulation for recording myogenic motor evoked potentials with the patient under general anesthesia. Neurosurgery, 39: 335-344.
32. Phillips, C.G., and Porter, R. 1964. The pyramidal projection to motoneurones of some muscle groups of the baboon's forelimb. Prog. Brain Res. 12: 222-242.
33. Phillips, C.G., and Porter, R. 1977. Corticospinal neurons: their role in movement. Academic Press, London.
34. Rothwell, J.C., Day, B.L., Berardelli, A., and Marsden, C.D. 1984. Effects of motor cortex stimulation on spinal interneurones in intact man. Exp. Brain Res. 54: 382-384.
35. Rothwell, J., Burke, D., Hicks, R., Stephen, J., Woodforth, I., and Crawford, M. 1994. Transcranial electrical stimulation of the motor cortex in man: further evidence for the site of activation. J. Physiol. 481(1): 243-250.
36. Zajac, F.E., and Young, J.L. 1980. Properties of stimulus trains producing maximum tension-time area per pulse from single motor units in medial gastrocnemius muscle of the cat. J. Neurophysiol. 43: 1206-1220.