Bone structure and volumetric BMD in overweight children: A longitudinal study

Journal of Bone and Mineral Research

Volumn 23, Issue 12, 2008, Pages 1946-1953

  Wetzsteon, Rachel J ^a   Petit, Moira A ^b   Macdonald, Heather M ^c   Hughes, Julie M ^b   Beck, Thomas J ^d   McKay, Heather A ^e,f  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c Department of Mechanical and Manufacturing Engineering ^*  (Canada)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f VANCOUVER COASTAL HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

BMD; Bone strength; Children; Obesity; pQCT

Indexed keywords

ANTHROPOMETRY; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; BONE DENSITY; BONE STRENGTH; BONE STRUCTURE; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MUSCLE CROSS SECTIONAL AREA; OBESITY; OUTCOME ASSESSMENT; PARAMETER; SCHOOL CHILD; SCORING SYSTEM; STRESS STRAIN INDEX; VOLUMETRY;

ADIPOSE TISSUE; ANTHROPOMETRY; BONE AND BONES; BONE DENSITY; CHILD; FEMALE; FRACTURES, BONE; HUMANS; LONGITUDINAL STUDIES; MALE; MUSCLES; OVERWEIGHT; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK;

EID: 56749149765     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.080810     Document Type: Article

References (44)

1. Nesbitt SD, Ashaye MO, Stettler N, Sorof JM, Goran MI, Parekh R, Falkner BE 2004 Overweight as a risk factor in children: A focus on ethnicity. Ethn Dis 14:94-110.
2. Dehghan M, Akhtar-Danesh N, Merchant AT 2005 Childhood obesity, prevalence and prevention. Nutr J 4:24.
3. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM 2006 Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 295:1549-1555.
4. Margolis KL, Ensrud KE, Schreiner PJ, Tabor HK 2000 Body size and risk for clinical fractures in older women. Study of Osteoporotic Fractures Research Group. Ann Intern Med 133:123-127.
5. Pesonen J, Sirola J, Tuppurainen M, Jurvelin J, Alhava E, Honkanen R, Kroger H 2005 High bone mineral density among perimenopausal women. Osteoporos Int 16:1899-1906.
6. Spaine LA, Bollen SR 1996 'The bigger they come ...': The relationship between body mass index and severity of ankle fractures. Injury 27:687-689.
7. Ellis KJ, Shypailo RJ, Wong WW, Abrams SA 2003 Bone mineral mass in overweight and obese children: Diminished or enhanced? Acta Diabetol 40(Suppl 1):S274-S277.
8. Leonard MB, Shults J, Wilson BA, Tershakovec AM, Zemel BS 2004 Obesity during childhood and adolescence augents bone mass and bone dimensions. Am J Clin Nutr 80:514-523.
9. Moro M, van der Meulen MC, Kiratli BJ, Marcus R, Bachrach LK, Carter DR 1996 Body mass is the primary determinant of midfemoral bone acquisition during adolescent growth. Bone 19:519-526.
10. Skaggs DL, Loro ML, Pitukcheewanont P, Tolo V, Gilsanz V 2001 Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fractures. J Bone Miner Res 16:1337-1342.
11. Goulding A, Jones IE, Taylor RW, Williams SM, Manning PJ 2001 Bone mineral density and body composition in boys with distal forearm fractures: A dual-energy x-ray absorptiometry study. J Pediatr 139:509-515.
12. Rocher E, Chappard C, Jaffre C, Benhamou CL, Courteix D 2008 Bone mineral density in prepubertal obese and control children: Relation to body weight, lean mass, and fat mass. J Bone Miner Metab 26:73-78.
13. Janicka A, Wren TA, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V 2007 Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab 92:143-147.
14. Pollock NK, Laing EM, Baile CA, Hamrick MW, Hall DB, Lewis RD 2007 Is adiposity advantageous for bone strength? A peripheral quantitative computed tomography study in late adolescent females. Am J Clin Nutr 86:1530-1538.
15. Gilsanz V, Wren T 2007 Assessment of bone acquisition in childhood and adolescence. Pediatrics 119(Suppl 2):S145-S149.
16. Clark EM, Ness AR, Bishop NJ, Tobias JH 2006 Association between bone mass and fractures in children: A prospective cohort study. J Bone Miner Res 21:1489-1495.
17. Frost HM 1997 Obesity, and bone strength and "mass": A tutorial based on insights from a new paradigm. Bone 21:211-214.
18. Biewener AA 1990 Biomechanics of mammalian terrestrial locomotion. Science 250:1097-1103.
19. Bamman MM, Newcomer BR, Larson-Meyer DE, Weinsier RL, Hunter GR 2000 Evaluation of the strength-size relationship in vivo using various muscle size indices. Med Sci Sports Exerc 32:1307-1313.
20. Petit MA, Beck TJ, Shults J, Zemel BS, Foster BJ, Leonard MB 2005 Proximal femur bone geometry is appropriately adapted to lean mass in overweight children and adolescents. Bone 36:568-576.
21. Naylor PJ, Macdonald HM, Reed KE, McKay HA 2006 Action Schools! BC: A socioecological approach to modifying chronic disease risk factors in elementary school children. Prey Chronic Dis 3:A60.
22. Naylor PJ, Macdonald HM, Zebedee JA, Reed KE, McKay HA 2006 Lessons learned from Action Schools! BC - an 'active school' model to promote physical activity in elementary schools. J Sci Med Sport 9:413-423.
23. Macdonald HM, Kontulainen SA, Khan KM, McKay HA 2007 Is a school-based physical activity intervention effective for increasing tibial bone strength in boys and girls? J Bone Miner Res 22:434-446.
24. Naylor PJ, Macdonald HM, Warburton DE, Reed KE, McKay HA 2008 An active school model to promote physical activity in elementary schools: Action schools! BC. Br J Sports Med 42:338-343.
25. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, Mei Z, Curtin LR, Roche AF, Johnson CL 2000 CDC growth charts: United States. Adv Data 314:1-27.
26. Tanner JM 1978 Foetus Into Man. Harvard Press, Cambridge, MA, USA.
27. Crocker PR, Bailey DA, Faulkner RA, Kowalski KC, McGrath R 1997 Measuring general levels of physical activity: Preliminary evidence for the Physical Activity Questionnaire for Older Children. Med Sci Sports Exerc 29:1344-1349.
28. Barr SI 1994 Associations of social and demographic variables with calcium intakes of high school students. J Am Diet Assoc 94:260-266.
29. Hologic 2000 Hologic QDR Series User's Guide. Hologic, Bedford, MA, USA.
30. Martin RB 1991 Determinants of the mechanical properties of bones. J Biomech 24(Suppl 1):79-88.
31. Kontulainen S, Sievanen H, Kannus P, Pasanen M, Vuori I 2002 Effect of long-term impact-loading on mass, size, and estimated strength of humerus and radius of female racquet-sports players: A peripheral quantitative computed tomography study between young and old starters and controls. J Bone Miner Res 17:2281-2289.
32. Selker F, Carter DR 1989 Scaling of long bone fracture strength with animal mass. J Biomech 22:1175-1183.
33. Manzoni P, Brambilla P, Pietrobelli A, Beccaria L, Bianchessi A, Mora S, Chiumello G 1996 Influence of body composition on bone mineral content in children and adolescents. Am J Clin Nutr 64:603-607.
34. Fischer S, Milinarsky A, Giadrosich V, Dib G, Arriagada M, Arinoviche R 2000 X-ray absorptiometry of bone in obese and eutrophic children from Valparaiso, Chile. J Rheumatol 27:1294-1296.
35. Goulding A, Taylor RW, Jones IE, McAuley KA, Manning PJ, Williams SM 2000 Overweight and obese children have low bone mass and area for their weight. Int J Obes Relat Metab Disord 24:627-632.
36. Goulding A, Taylor RW, Jones IE, Manning PJ, Williams SM 2002 Spinal overload: A concern for obese children and adolescents? Osteoporos Int 13:835-840.
37. Frost HM 2003 Bone's mechanostat: A 2003 update. Anat Rec A Discov Mol Cell Evol Biol 275:1081-1101.
38. Goulding A, Grant AM, Williams SM 2005 Bone and body composition of children and adolescents with repeated forearm fractures. J Bone Miner Res 20:2090-2096.
39. Turner CH, Robling AG 2003 Designing exercise regimens to increase bone strength. Exerc Sport Sci Rev 31:45-50.
40. Goulding A 2007 Risk factors for fractures in normally active children and adolescents. Med Sports Sci 51:102-120.
41. Donahue SW, Galley SA 2006 Microdamage in bone: Implications for fracture, repair, remodeling, and adaptation. Crit Rev Biomed Eng 34:215-271.
42. Nishimura R, Sano H, Matsudaira T, Miyashita Y, Morimoto A, Shirasawa T, Takahashi E, Kawaguchi T, Tajima N 2007 Childhood obesity and its relation to serum adiponectin and leptin: A report from a population-based study. Diabetes Res Clin Pract 76:245-250.
43. Ahima RS, Osei SY 2008 Adipokines in obesity. Front Horm Res 36:182-197.
44. Cirmanova V, Bayer M, Starka L, Zajickova K 2008 The effect of leptin on bone - an evolving concept of action. Physiol Res 57(Suppl 1):S143-S153.