Body fat reducing effect and safety of the beverage containing polyphenols derived from Japanese pagoda tree (enzymatically modified isoquercitrin) in overweight and obese subjects

Japanese Pharmacology and Therapeutics

Volumn 36, Issue 10, 2008, Pages 919-930

  Yoshimura, Makiko ^a   Maeda, Akifumi ^a   Abe, Keiichi ^a   Ohta, Hiromi ^a   Kiso, Yoshinobu ^a   Takehara, Isao ^b   Fukuhara, Ikuo ^c   Sakane, Naoki ^d  

^a SUNTORY LTD   (Japan)

^b New Drug Development Research Center Inc   (Japan)

^c Fukuhara Clinic   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION KYOTO MEDICAL CENTER   (Japan)

Author keywords

Body fat; Fat oxidation; Japanese pagoda tree polyphenols; Metabolic syndrome; Quercetin glucoside

Indexed keywords

ISOQUERCITRIN; POLYPHENOL DERIVATIVE;

ABDOMINAL FAT; ABSENCE OF SIDE EFFECTS; ARTICLE; BEVERAGE; BODY FAT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ENERGY METABOLISM; EXERCISE; FEMALE; FOOD COMPOSITION; HUMAN; INTRAABDOMINAL FAT; LIPID OXIDATION; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; OBESITY; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SUBCUTANEOUS FAT; TREATMENT DURATION; WAIST CIRCUMFERENCE;

EID: 56749144043     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Japanese source.
2. Japanese source.
3. Japanese source.
4. Ono Y, Tomimori N, Fukui Y, Asami S, Shibata H, et al. Absorption and metabolism of Quercetin-3-O-glucoside (Q3G), and its enhancing effect on plasma antioxidative capacity. 2nd International Conference on Polyphenols and Health 2005.
5. Japanese source.
6. Arai Y, Watanabe S, Kimura M, Shimoi K, Mochizuki R, Kinae N. Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration. J Nutr 2000; 130: 2243-50.
7. Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol 2008 May 13; 585 (2-3): 325-37. Epub 2008 Mar 18.
8. Yamamoto Y, Oue E. Antihypertensive effect of quercetin in rats fed with a high-fat high-sucrose diet. Biosci Biotechnol Biochem 2006; 70 (4): 933-9.
9. Kuppusamy UR, Das NP. Effects of flavonoids on cyclic AMP phosphodiesterase and lipid mobilization in rat adipocytes. Biochem Pharmacol 1992; 44 (7): 1307-15.
10. Kuppusamy UR, Das NP. Potentiation of β-adrenoceptor agonist-mediated lipolysis by quercetin and fisetin in isolated rat adipocytes. Biochem Pharmacol 1994; 47 (3): 521-9.
11. Juźwiak S, Wójcicki J, Mokrzycki K, Marchlewicz M, Białecka M, Wenda-Rózewicka L, et al. Effect of quercetin on the experimental hyperlipidemia and atherosclerosis in rabbits. Pharmacol Rep 2005; 57 (5): 604-9.
12. (submitted to)
13. Takashima S, Kataoka K, Shibata E, Hoshino E. The long term intake of catechins improves lipid catabolism during exercise. Prog Med 2004; 24 (12): 3371-79.
14. Bursztein, Energy Metabolism Indirect Calorimetry and Nutrition. p.59, 62.
15. Tokunaga K, Matsuzawa Y, Ishikawa K, Tarui S. A novel technique for the determination of body fat by computed tomography. Int J Obes 1983; 7 (5): 437-45.
16. Japanese source.
17. Akiyama T, Washino T, Yamada T, Koda T, Maitani T. Constituents of enzymatically modified isoquercitrin and enzymatically modified rutin. J Food Hyg Soc Japan 2000; 41 (1): 54-60.
18. Watt MJ, Holmes AG, Pinnamaneni SK, Garnham. AP, Steinberg GR, Kemp BE, et al. Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue. Am J Physiol Endocrinol Metab 2006 Mar; 290 (3): E500-8. Epub 2005 Sep 27.
19. Japanese source.