Blockade of calcineurin reverses cardiac hypertrophy and induces the down-regulation of JNK mRNA expression in renovascular hypertensive rats

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 9, Issue 3, 2008, Pages 139-145

  Sheng, Hongzhuan ^a,b   Zhu, Jianhua ^b   Wu, Xiaohui ^b   Zhang, Jinan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

Calcineurin; Cardiac hypertrophy; Mitogen activated protein kinase; Rats; Renovascular hypertension

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; CYCLOSPORIN A; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLACEBO; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE FILLING; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; LEG LENGTH; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RENOVASCULAR HYPERTENSION; SIGNAL TRANSDUCTION; TIBIA; TREATMENT OUTCOME;

ANIMALS; BLOOD PRESSURE; CALCINEURIN; CARDIOMEGALY; CYCLOSPORINE; DIASTOLE; DOWN-REGULATION; HEART FUNCTION TESTS; HEART VENTRICLES; HYPERTENSION, RENOVASCULAR; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SYSTOLE;

EID: 56749131202     PISSN: 14703203     EISSN: None     Source Type: Journal    
DOI: 10.1177/1470320308096048     Document Type: Article

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