메뉴 건너뛰기




Volumn 21, Issue 6, 2008, Pages 754-761

Ependymomas of the adult: Molecular biology and treatment

Author keywords

Ependymomas; Molecular biology; Prognostic factors; Treatment

Indexed keywords

CARBOPLATIN; DIAZIQUONE; ETOPOSIDE; IDARUBICIN; IFOSFAMIDE; IMATINIB; IRINOTECAN; ISOTRETINOIN; TAMOXIFEN; TEMOZOLOMIDE; TOPOTECAN; TUMOR MARKER;

EID: 56749109572     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/WCO.0b013e328317efe8     Document Type: Review
Times cited : (72)

References (106)
  • 2
    • 33845949021 scopus 로고    scopus 로고
    • Survival analysis of 459 adult patients with primary spinal cancer in England and Wales: A population-based study
    • The first nationwide population-based study on adult patients with spinal cancer
    • Tseng JH, Tseng MY. Survival analysis of 459 adult patients with primary spinal cancer in England and Wales: a population-based study. Surg Neurol 2007; 67:53-58. The first nationwide population-based study on adult patients with spinal cancer.
    • (2007) Surg Neurol , vol.67 , pp. 53-58
    • Tseng, J.H.1    Tseng, M.Y.2
  • 3
    • 0035687515 scopus 로고    scopus 로고
    • Spinal cord gliomas
    • Henson JW. Spinal cord gliomas. Curr Opin Neurol 2001; 14:679-682.
    • (2001) Curr Opin Neurol , vol.14 , pp. 679-682
    • Henson, J.W.1
  • 4
    • 34249311059 scopus 로고    scopus 로고
    • Ependymoma
    • A thorough review of ependymomas of the adult
    • Reni M, Gatta G, Mazza E, et al. Ependymoma. Crit Rev Oncol Hematol 2007; 63:81-89. A thorough review of ependymomas of the adult.
    • (2007) Crit Rev Oncol Hematol , vol.63 , pp. 81-89
    • Reni, M.1    Gatta, G.2    Mazza, E.3
  • 5
    • 33644820339 scopus 로고    scopus 로고
    • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
    • Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 2006; 9:157-173.
    • (2006) Cancer Cell , vol.9 , pp. 157-173
    • Phillips, H.S.1    Kharbanda, S.2    Chen, R.3
  • 6
    • 39749116268 scopus 로고    scopus 로고
    • Medulloblastoma: From molecular pathology to therapy
    • Rossi A, Caracciolo V, Russo G, et al. Medulloblastoma: from molecular pathology to therapy. Clin Cancer Res 2008; 14:971-976.
    • (2008) Clin Cancer Res , vol.14 , pp. 971-976
    • Rossi, A.1    Caracciolo, V.2    Russo, G.3
  • 7
    • 0032801037 scopus 로고    scopus 로고
    • Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas
    • Ebert C, von Haken M, Meyer-Puttlitz B, et al. Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas. Am J Pathol 1999; 155:627-632.
    • (1999) Am J Pathol , vol.155 , pp. 627-632
    • Ebert, C.1    von Haken, M.2    Meyer-Puttlitz, B.3
  • 8
    • 0035869674 scopus 로고    scopus 로고
    • Molecular genetic alterations on chromosomes 11 and 22 in ependymomas
    • Lamszus K, Lachenmayer L, Heinemann U, et al. Molecular genetic alterations on chromosomes 11 and 22 in ependymomas. Int J Cancer 2001; 91:803-808.
    • (2001) Int J Cancer , vol.91 , pp. 803-808
    • Lamszus, K.1    Lachenmayer, L.2    Heinemann, U.3
  • 9
    • 0035097365 scopus 로고    scopus 로고
    • Low frequency of chromosomal imbalances in anaplastic ependymomas as detected by comparative genomic hybridization
    • Scheil S, Bruderlein S, Eicker M, et al. Low frequency of chromosomal imbalances in anaplastic ependymomas as detected by comparative genomic hybridization. Brain Pathol 2001; 11:133-143.
    • (2001) Brain Pathol , vol.11 , pp. 133-143
    • Scheil, S.1    Bruderlein, S.2    Eicker, M.3
  • 10
    • 0036262155 scopus 로고    scopus 로고
    • Correlation between localization, age, and chromosomal imbalances in ependymal tumours as detected by CGH
    • Jeuken JW, Sprenger SH, Gilhuis J, et al. Correlation between localization, age, and chromosomal imbalances in ependymal tumours as detected by CGH. J Pathol 2002; 197:238-244.
    • (2002) J Pathol , vol.197 , pp. 238-244
    • Jeuken, J.W.1    Sprenger, S.H.2    Gilhuis, J.3
  • 11
    • 34247396134 scopus 로고    scopus 로고
    • Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics
    • Modena P, Lualdi E, Facchinetti F, et al. Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics. J Clin Oncol 2006; 24:5223-5233.
    • (2006) J Clin Oncol , vol.24 , pp. 5223-5233
    • Modena, P.1    Lualdi, E.2    Facchinetti, F.3
  • 12
    • 0035099106 scopus 로고    scopus 로고
    • Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups
    • Hirose Y, Aldape K, Bollen A, et al. Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups. Am J Pathol 2001; 58:1137-1143.
    • (2001) Am J Pathol , vol.58 , pp. 1137-1143
    • Hirose, Y.1    Aldape, K.2    Bollen, A.3
  • 13
    • 0034903274 scopus 로고    scopus 로고
    • Gain of 1q and loss of 22 are the most common changes detected by comparative genomic hybridization in paediatric ependymoma
    • Ward S, Harding B, Wilkins P, et al. Gain of 1q and loss of 22 are the most common changes detected by comparative genomic hybridization in paediatric ependymoma. Genes Chromosomes Cancer 2001; 32:59-66.
    • (2001) Genes Chromosomes Cancer , vol.32 , pp. 59-66
    • Ward, S.1    Harding, B.2    Wilkins, P.3
  • 14
    • 18344376523 scopus 로고    scopus 로고
    • Genetic abnormalities detected in ependymomas by comparative genomic hybridization
    • Carter M, Nicholson J, Ross R, et al. Genetic abnormalities detected in ependymomas by comparative genomic hybridization. Br J Cancer 2002; 86:929-939.
    • (2002) Br J Cancer , vol.86 , pp. 929-939
    • Carter, M.1    Nicholson, J.2    Ross, R.3
  • 15
    • 33646262611 scopus 로고    scopus 로고
    • Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma
    • Mendryzk F, Korshunov A, Benner A, et al. Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma. Clin Cancer Res 2006; 12:2070-2079.
    • (2006) Clin Cancer Res , vol.12 , pp. 2070-2079
    • Mendryzk, F.1    Korshunov, A.2    Benner, A.3
  • 16
    • 0036793917 scopus 로고    scopus 로고
    • ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease
    • Gilbertson RJ, Bentley L, Hernan R, et al. ERBB receptor signaling promotes ependymoma cell proliferation and represents a potential novel therapeutic target for this disease. Clin Cancer Res 2002; 8:3054-3064.
    • (2002) Clin Cancer Res , vol.8 , pp. 3054-3064
    • Gilbertson, R.J.1    Bentley, L.2    Hernan, R.3
  • 17
    • 21544465080 scopus 로고    scopus 로고
    • Alpha(v)beta(3) Integrin in central nervous system tumors
    • Lim M, Guccione S, Haddix T, et al. Alpha(v)beta(3) Integrin in central nervous system tumors. Hum Pathol 2005; 36:665-669.
    • (2005) Hum Pathol , vol.36 , pp. 665-669
    • Lim, M.1    Guccione, S.2    Haddix, T.3
  • 18
    • 33749026635 scopus 로고    scopus 로고
    • Expression of cyclo-oxygenase-2 in ependymal tumors
    • Roma AA, Prayson RA. Expression of cyclo-oxygenase-2 in ependymal tumors. Neuropathology 2006; 26:422-428.
    • (2006) Neuropathology , vol.26 , pp. 422-428
    • Roma, A.A.1    Prayson, R.A.2
  • 19
    • 34249888765 scopus 로고    scopus 로고
    • Identification of novel biomarkers in pediatric primitive neuroectodermal tumors and ependymomas by proteomewide analysis
    • A study identifying some tumor-specific proteins in pediatric primitive neuroectodermal tumors and ependymomas
    • De Bont JM, den Boer ML, Kros JM, et al. Identification of novel biomarkers in pediatric primitive neuroectodermal tumors and ependymomas by proteomewide analysis. J Neuropathol Exp Neurol 2007; 66:505-516. A study identifying some tumor-specific proteins in pediatric primitive neuroectodermal tumors and ependymomas.
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 505-516
    • De Bont, J.M.1    den Boer, M.L.2    Kros, J.M.3
  • 20
    • 13244265850 scopus 로고    scopus 로고
    • A PDGFRA promoter polymorphism, which disrupts the binding of ZNF148, is associated with primitive neuroectodermal tumours and ependymomas
    • De Bustos C, Smits A, Stromberg B, et al. A PDGFRA promoter polymorphism, which disrupts the binding of ZNF148, is associated with primitive neuroectodermal tumours and ependymomas. J Med Genet 2005; 42:31-37.
    • (2005) J Med Genet , vol.42 , pp. 31-37
    • De Bustos, C.1    Smits, A.2    Stromberg, B.3
  • 21
    • 0142151108 scopus 로고    scopus 로고
    • Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age
    • Korshunov A, Neben K, Wrobel G, et al. Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age. Am J Pathol 2003; 163:1721-1727.
    • (2003) Am J Pathol , vol.163 , pp. 1721-1727
    • Korshunov, A.1    Neben, K.2    Wrobel, G.3
  • 22
    • 14644423234 scopus 로고    scopus 로고
    • Microarray analysis of pediatric ependymoma identifies a cluster of 112 candidate genes including four transcripts at 22q12.1-q13.3
    • Suarez-Merino B, Hubank M, Revesz T, et al. Microarray analysis of pediatric ependymoma identifies a cluster of 112 candidate genes including four transcripts at 22q12.1-q13.3. Neuro Oncol 2005; 7:20-31.
    • (2005) Neuro Oncol , vol.7 , pp. 20-31
    • Suarez-Merino, B.1    Hubank, M.2    Revesz, T.3
  • 23
    • 33947393501 scopus 로고    scopus 로고
    • Ependymoma gene expression profiles associated with histological subtype, proliferation, and patient survival
    • A study investigating the relationship between gene expression profile and proliferation index, histologic subtype, location and outcome in pediatric and adult ependymomas
    • Lukashova-v Zangen I, Kneitz S, Monoranu CM, et al. Ependymoma gene expression profiles associated with histological subtype, proliferation, and patient survival. Acta Neuropathol 2007; 113:325-337. A study investigating the relationship between gene expression profile and proliferation index, histologic subtype, location and outcome in pediatric and adult ependymomas.
    • (2007) Acta Neuropathol , vol.113 , pp. 325-337
    • Lukashova-v Zangen, I.1    Kneitz, S.2    Monoranu, C.M.3
  • 24
    • 2442651661 scopus 로고    scopus 로고
    • Analysis of HIC-1 methylation and transcription in human ependymomas
    • Waha A, Koch A, Hartmann W, et al. Analysis of HIC-1 methylation and transcription in human ependymomas. Int J Cancer 2004; 110:542-549.
    • (2004) Int J Cancer , vol.110 , pp. 542-549
    • Waha, A.1    Koch, A.2    Hartmann, W.3
  • 25
    • 22744444861 scopus 로고    scopus 로고
    • Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma
    • Hamilton DW, Lusher ME, Lindsey JC, et al. Epigenetic inactivation of the RASSF1A tumour suppressor gene in ependymoma. Cancer Lett 2005; 227:75-81.
    • (2005) Cancer Lett , vol.227 , pp. 75-81
    • Hamilton, D.W.1    Lusher, M.E.2    Lindsey, J.C.3
  • 26
    • 33645988574 scopus 로고    scopus 로고
    • Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma
    • Michalowski MB, de Fraipont F, Michelland S, et al. Methylation of RASSF1A and TRAIL pathway-related genes is frequent in childhood intracranial ependymomas and benign choroid plexus papilloma. Cancer Genet Cytogenet 2006; 166:74-81.
    • (2006) Cancer Genet Cytogenet , vol.166 , pp. 74-81
    • Michalowski, M.B.1    de Fraipont, F.2    Michelland, S.3
  • 27
    • 26644435531 scopus 로고    scopus 로고
    • Radial glia cells are candidate stem cells of ependymoma
    • Taylor MD, Poppleton H, Fuller C, et al. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 2005; 8:323-335.
    • (2005) Cancer Cell , vol.8 , pp. 323-335
    • Taylor, M.D.1    Poppleton, H.2    Fuller, C.3
  • 28
    • 33846189405 scopus 로고    scopus 로고
    • Stem cells of ependymoma
    • A thorough review of current knowledge on the role of stem cells in ependymomas
    • Poppleton H, Gilbertson RJ. Stem cells of ependymoma. Br J Cancer 2007; 96:6-10. A thorough review of current knowledge on the role of stem cells in ependymomas.
    • (2007) Br J Cancer , vol.96 , pp. 6-10
    • Poppleton, H.1    Gilbertson, R.J.2
  • 29
    • 20044372154 scopus 로고    scopus 로고
    • MGMT gene silencing and benefit from temozolomide in glioblastoma
    • Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005; 352:997-1003.
    • (2005) N Engl J Med , vol.352 , pp. 997-1003
    • Hegi, M.E.1    Diserens, A.C.2    Gorlia, T.3
  • 30
    • 31544464704 scopus 로고    scopus 로고
    • Targeted modulation of MGMT: Clinical implications
    • Liu L, Gerson SL. Targeted modulation of MGMT: clinical implications. Clin Cancer Res 2006; 12:328-331.
    • (2006) Clin Cancer Res , vol.12 , pp. 328-331
    • Liu, L.1    Gerson, S.L.2
  • 31
    • 0005007063 scopus 로고    scopus 로고
    • Intracranial ependymomas
    • Kaye AH, Laws ER, editors. London: Churchill Livingstone, pp
    • Kulkarni AV, Drake JR. Intracranial ependymomas. Brain tumors. In: Kaye AH, Laws ER, editors. London: Churchill Livingstone, pp. 541-550.
    • Brain tumors , pp. 541-550
    • Kulkarni, A.V.1    Drake, J.R.2
  • 32
    • 24944560563 scopus 로고    scopus 로고
    • Long-term outcome in patients harboring intracranial ependymoma
    • Kawabata Y, Takahashi JA, Arakawa Y, et al. Long-term outcome in patients harboring intracranial ependymoma. J Neurosurg 2005; 103:31-37.
    • (2005) J Neurosurg , vol.103 , pp. 31-37
    • Kawabata, Y.1    Takahashi, J.A.2    Arakawa, Y.3
  • 33
    • 19944431588 scopus 로고    scopus 로고
    • Postoperative radiation therapy for grade II and III intracranial ependymoma
    • Mansur DB, Perry A, Rajaram V, et al. Postoperative radiation therapy for grade II and III intracranial ependymoma. Int J Radiat Oncol Biol Phys 2005; 61:387-391.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 387-391
    • Mansur, D.B.1    Perry, A.2    Rajaram, V.3
  • 34
    • 29644444982 scopus 로고    scopus 로고
    • Ependymoma: New therapeutic approaches including radiation and chemotherapy
    • Merchant TE, Fouladi M. Ependymoma: new therapeutic approaches including radiation and chemotherapy. J Neurooncol 2005; 75:287-299.
    • (2005) J Neurooncol , vol.75 , pp. 287-299
    • Merchant, T.E.1    Fouladi, M.2
  • 35
    • 56749124350 scopus 로고    scopus 로고
    • Ependymomas
    • Black PM, Loeffler JS, editors, Philadelphia: Lippincot Williams & Wilkins;
    • Goldwein JW, Sutton LM. Ependymomas. In: Black PM, Loeffler JS, editors. Cancer of the nervous system. Philadelphia: Lippincot Williams & Wilkins; 2005. pp. 533-542.
    • (2005) Cancer of the nervous system , pp. 533-542
    • Goldwein, J.W.1    Sutton, L.M.2
  • 36
    • 0036898809 scopus 로고    scopus 로고
    • Intracranial ependymomas in adult patients: Analyses of prognostic factors
    • Guyotat J, Signorelli F, Desme S, et al. Intracranial ependymomas in adult patients: analyses of prognostic factors. J Neurooncol 2002; 60:255-268.
    • (2002) J Neurooncol , vol.60 , pp. 255-268
    • Guyotat, J.1    Signorelli, F.2    Desme, S.3
  • 37
    • 12144287205 scopus 로고    scopus 로고
    • A multicenter study of the prognosis and treatment of adult brain ependymal tumors
    • Reni M, Brandes AA, Vavassori V, et al. A multicenter study of the prognosis and treatment of adult brain ependymal tumors. Cancer 2004; 100:1221-1229.
    • (2004) Cancer , vol.100 , pp. 1221-1229
    • Reni, M.1    Brandes, A.A.2    Vavassori, V.3
  • 38
    • 34249698649 scopus 로고    scopus 로고
    • Multicentric French study on adult intracranial ependymomas: Prognostic factors analysis and therapeutic considerations from a cohort of 152 patients
    • The largest multiinstitutional retrospective analysis of intracranial ependymomas in adult patients, based on central pathology review
    • Metellus P, Barrie M, Figarella-Branger D, et al. Multicentric French study on adult intracranial ependymomas: prognostic factors analysis and therapeutic considerations from a cohort of 152 patients. Brain 2007; 130:1338-1349. The largest multiinstitutional retrospective analysis of intracranial ependymomas in adult patients, based on central pathology review.
    • (2007) Brain , vol.130 , pp. 1338-1349
    • Metellus, P.1    Barrie, M.2    Figarella-Branger, D.3
  • 39
    • 0025878703 scopus 로고
    • Ependymoma: Internal correlations among pathological signs: the anaplastic variant
    • Schiffer D, Chio A, Cravioto H, et al. Ependymoma: internal correlations among pathological signs: the anaplastic variant. Neurosurgery 1991; 29:206-210.
    • (1991) Neurosurgery , vol.29 , pp. 206-210
    • Schiffer, D.1    Chio, A.2    Cravioto, H.3
  • 41
    • 1542284097 scopus 로고    scopus 로고
    • The histologic grade is a main prognostic factor for patients with intracranial ependymomas treated in the microneurosurgical era: An analysis of 258 patients
    • Korshunov A, Golanov A, Sycheva R, et al. The histologic grade is a main prognostic factor for patients with intracranial ependymomas treated in the microneurosurgical era: an analysis of 258 patients. Cancer 2004; 100:1230-1237.
    • (2004) Cancer , vol.100 , pp. 1230-1237
    • Korshunov, A.1    Golanov, A.2    Sycheva, R.3
  • 42
    • 3042834730 scopus 로고    scopus 로고
    • Ki-67 immunolabeling index is an accurate predictor of outcome in patients with intracranial ependymoma
    • Wolfsberger S, Fischer I, Höftberger R, et al. Ki-67 immunolabeling index is an accurate predictor of outcome in patients with intracranial ependymoma. Am J Surg Pathol 2004; 28:914-920.
    • (2004) Am J Surg Pathol , vol.28 , pp. 914-920
    • Wolfsberger, S.1    Fischer, I.2    Höftberger, R.3
  • 43
    • 30744440640 scopus 로고    scopus 로고
    • Identification of relevant prognostic histopathologic features in 89 intracranial ependymomas, excluding myxopapillary ependymomas and subependymomas
    • Kurt E, Zheng PP, Hop WC, et al. Identification of relevant prognostic histopathologic features in 89 intracranial ependymomas, excluding myxopapillary ependymomas and subependymomas. Cancer 2006; 106:388-395.
    • (2006) Cancer , vol.106 , pp. 388-395
    • Kurt, E.1    Zheng, P.P.2    Hop, W.C.3
  • 44
    • 0030982372 scopus 로고    scopus 로고
    • Anaplastic ependymoma: Treatment of pediatric patients with or without craniospinal radiation therapy
    • Merchant TE, Haida T, Wang MH, et al. Anaplastic ependymoma: treatment of pediatric patients with or without craniospinal radiation therapy. J Neurosurg 1997; 86:943-949.
    • (1997) J Neurosurg , vol.86 , pp. 943-949
    • Merchant, T.E.1    Haida, T.2    Wang, M.H.3
  • 45
    • 0033038018 scopus 로고    scopus 로고
    • Supratentorial ependymomas in adult patients
    • Schwartz TH, Kim S, Glick RS, et al. Supratentorial ependymomas in adult patients. Neurosurgery 1999; 44:721-731.
    • (1999) Neurosurgery , vol.44 , pp. 721-731
    • Schwartz, T.H.1    Kim, S.2    Glick, R.S.3
  • 46
    • 47149109289 scopus 로고    scopus 로고
    • Metellus P, Figarella-Branger D, Guyotat J, et al. Supratentorial ependymomas: prognostic factors and outcome analysis in a retrospective series of 46 adult patients. Cancer 2008; 113.175-185. A multiinstitutional retrospective analysis of outcome of adult supratentorial ependymomas.
    • Metellus P, Figarella-Branger D, Guyotat J, et al. Supratentorial ependymomas: prognostic factors and outcome analysis in a retrospective series of 46 adult patients. Cancer 2008; 113.175-185. A multiinstitutional retrospective analysis of outcome of adult supratentorial ependymomas.
  • 47
    • 0025727233 scopus 로고
    • The prognostic significance of postoperative residual tumor in ependymoma
    • Healey EA, Barnes PD, Kupsky WJ, et al. The prognostic significance of postoperative residual tumor in ependymoma. Neurosurgery 1991; 28:666-671.
    • (1991) Neurosurgery , vol.28 , pp. 666-671
    • Healey, E.A.1    Barnes, P.D.2    Kupsky, W.J.3
  • 48
    • 0036221560 scopus 로고    scopus 로고
    • Intracranial ependymomas: An analysis of prognostic factors and patterns of failure
    • Paulino AC, Wen BC, Buatti JM, et al. Intracranial ependymomas: an analysis of prognostic factors and patterns of failure. Am J Clin Oncol 2002; 25:117-122.
    • (2002) Am J Clin Oncol , vol.25 , pp. 117-122
    • Paulino, A.C.1    Wen, B.C.2    Buatti, J.M.3
  • 49
    • 18744370757 scopus 로고    scopus 로고
    • Is gross-total resection sufficient treatment for posterior fossa ependymomas?
    • Rogers L, Pueschel J, Spetzler R, et al. Is gross-total resection sufficient treatment for posterior fossa ependymomas? J Neurosurg 2005; 102:629-636.
    • (2005) J Neurosurg , vol.102 , pp. 629-636
    • Rogers, L.1    Pueschel, J.2    Spetzler, R.3
  • 50
    • 0029791466 scopus 로고    scopus 로고
    • Disseminated ependymomas of the central nervous system
    • Rezai AR, Woo HH, Lee M, et al. Disseminated ependymomas of the central nervous system. J Neurosurg 1996; 85:618-624.
    • (1996) J Neurosurg , vol.85 , pp. 618-624
    • Rezai, A.R.1    Woo, H.H.2    Lee, M.3
  • 51
    • 0036801605 scopus 로고    scopus 로고
    • Ependymoma in childhood: Prognostic factors, extent of surgery, and adjuvant therapy
    • Van Veelen-Vincent ML, Pierre-Kahn A, Kalifa C, et al. Ependymoma in childhood: prognostic factors, extent of surgery, and adjuvant therapy. J Neurosurg 2002; 97:827-835.
    • (2002) J Neurosurg , vol.97 , pp. 827-835
    • Van Veelen-Vincent, M.L.1    Pierre-Kahn, A.2    Kalifa, C.3
  • 52
    • 0034859172 scopus 로고    scopus 로고
    • Surveillance neuroimaging in childhood intracranial ependymoma: How effective, how often, and for how long?
    • Good CD, Wade AM, Hayward RD, et al. Surveillance neuroimaging in childhood intracranial ependymoma: how effective, how often, and for how long? J Neurosurg 2001; 94:27-32.
    • (2001) J Neurosurg , vol.94 , pp. 27-32
    • Good, C.D.1    Wade, A.M.2    Hayward, R.D.3
  • 54
    • 1942487195 scopus 로고    scopus 로고
    • Review of radiotherapy dose and volume for intracranial ependy-moma
    • Taylor RE. Review of radiotherapy dose and volume for intracranial ependy-moma. Pediatr Blood Cancer 2004; 42:457-460.
    • (2004) Pediatr Blood Cancer , vol.42 , pp. 457-460
    • Taylor, R.E.1
  • 55
    • 0023009914 scopus 로고
    • Intracranial ependymomas: Results of treatment with partial or whole brain irradiation without spinal irradiation
    • Wallner KE, Wara WM, Sheline GE, et al. Intracranial ependymomas: results of treatment with partial or whole brain irradiation without spinal irradiation. Int J Radiat Oncol Biol Phys 1986; 12:1937-1941.
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1937-1941
    • Wallner, K.E.1    Wara, W.M.2    Sheline, G.E.3
  • 56
    • 0026042708 scopus 로고
    • The role of prophylactic spinal cord irradiation in localized intracranial ependymoma
    • Vanuytsel L, Brada M. The role of prophylactic spinal cord irradiation in localized intracranial ependymoma. Int J Radiat Oncol Biol Phys 1991; 21:825-830.
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 825-830
    • Vanuytsel, L.1    Brada, M.2
  • 57
    • 0026769760 scopus 로고
    • Intracranial ependymoma: Long term results of a policy of surgery and radiotherapy
    • Vanuytsel L, Bessell EM, Ashley SE, et al. Intracranial ependymoma: long term results of a policy of surgery and radiotherapy. Int J Radiat Oncol Biol Phys 1992; 23:313-319.
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 313-319
    • Vanuytsel, L.1    Bessell, E.M.2    Ashley, S.E.3
  • 58
    • 0032435417 scopus 로고    scopus 로고
    • The results of radiotherapy for ependymomas: The Mayo Clinic experience
    • Schild SE, Nisi K, Scheithauer BW, et al. The results of radiotherapy for ependymomas: the Mayo Clinic experience. Int J Radiat Oncol Biol Phys 1998; 42:953-958.
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 953-958
    • Schild, S.E.1    Nisi, K.2    Scheithauer, B.W.3
  • 59
    • 0033958949 scopus 로고    scopus 로고
    • Timmermann B1 Kortmann RD, Kuhl J, et al. Combined postoperative irradiation and chemotherapy for anaplastic ependymomas in childhood: results of the German prospective trials HIT 88/89 and HIT 91. Int J Radiat Oncol Biol Phys 2000; 46:287-295.
    • Timmermann B1 Kortmann RD, Kuhl J, et al. Combined postoperative irradiation and chemotherapy for anaplastic ependymomas in childhood: results of the German prospective trials HIT 88/89 and HIT 91. Int J Radiat Oncol Biol Phys 2000; 46:287-295.
  • 60
    • 0035283723 scopus 로고    scopus 로고
    • The local field in infratentorial ependymoma: Does the entire posterior fossa need to be treated?
    • Paulino AC. The local field in infratentorial ependymoma: does the entire posterior fossa need to be treated? Int J Radiat Oncol Biol Phys 2001; 49:757-761.
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 757-761
    • Paulino, A.C.1
  • 61
    • 0031951109 scopus 로고    scopus 로고
    • Intracranial ependymoma in the adult patient: Successful treatment with surgery and radiotherapy
    • Donahue B, Steinfeld A. Intracranial ependymoma in the adult patient: successful treatment with surgery and radiotherapy. J Neurooncol 1998; 37:131-133.
    • (1998) J Neurooncol , vol.37 , pp. 131-133
    • Donahue, B.1    Steinfeld, A.2
  • 62
    • 0017715984 scopus 로고
    • Ependymoma: A follow-up study of 101 cases
    • Mork SJ, Loken AC. Ependymoma: a follow-up study of 101 cases. Cancer 1977; 40:907-915.
    • (1977) Cancer , vol.40 , pp. 907-915
    • Mork, S.J.1    Loken, A.C.2
  • 63
    • 0020610962 scopus 로고
    • Improved survival in cases of intracranial ependymoma after radiation therapy. Late report and recommendations
    • Salazar OM, Castro-Vita H, VanHoutte P, et al. Improved survival in cases of intracranial ependymoma after radiation therapy. Late report and recommendations. J Neurosurg 1983; 59:652-659.
    • (1983) J Neurosurg , vol.59 , pp. 652-659
    • Salazar, O.M.1    Castro-Vita, H.2    VanHoutte, P.3
  • 64
    • 0023627752 scopus 로고
    • Postoperative radiotherapy of intracranial ependymoma in pediatric and adult patients
    • Shaw EG, Evans RG, Scheithauer BW, et al. Postoperative radiotherapy of intracranial ependymoma in pediatric and adult patients. Int J Radiat Oncol Biol Phys 1987; 13:1457-1462.
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 1457-1462
    • Shaw, E.G.1    Evans, R.G.2    Scheithauer, B.W.3
  • 65
    • 0029886914 scopus 로고    scopus 로고
    • Deferring adjuvant therapy for totally resected intracranial ependymoma
    • Awaad YM, Allen JC, Miller DC, et al. Deferring adjuvant therapy for totally resected intracranial ependymoma. Pediatr Neurol 1996; 14:216-219.
    • (1996) Pediatr Neurol , vol.14 , pp. 216-219
    • Awaad, Y.M.1    Allen, J.C.2    Miller, D.C.3
  • 66
    • 0032449190 scopus 로고    scopus 로고
    • Treatment of intracranial ependymoma by surgery alone
    • Hukin J, Epstein F, Letton D, et al. Treatment of intracranial ependymoma by surgery alone. Pediatr Neurosurg 1998; 29:40-45.
    • (1998) Pediatr Neurosurg , vol.29 , pp. 40-45
    • Hukin, J.1    Epstein, F.2    Letton, D.3
  • 67
    • 0034651871 scopus 로고    scopus 로고
    • Stereotactic radiosurgery for recurrence ependymomas
    • Stafford SL, Pollock BE, Foots RL, et al. Stereotactic radiosurgery for recurrence ependymomas. Cancer 2000; 88:870-875.
    • (2000) Cancer , vol.88 , pp. 870-875
    • Stafford, S.L.1    Pollock, B.E.2    Foots, R.L.3
  • 68
    • 1342265803 scopus 로고    scopus 로고
    • The efficacy of stereotactic radiosurgery in the management of intracranial ependymoma
    • Mansur DB, Drzymala RE, Rich KM, et al. The efficacy of stereotactic radiosurgery in the management of intracranial ependymoma. J Neurooncol 2004; 66:187-190.
    • (2004) J Neurooncol , vol.66 , pp. 187-190
    • Mansur, D.B.1    Drzymala, R.E.2    Rich, K.M.3
  • 69
    • 33749394674 scopus 로고    scopus 로고
    • Local radiotherapeutic management of ependymomas with fractionated stereotactic radiotherapy (FSRT)
    • Combs SE, Thilmann C, Debus J, et al. Local radiotherapeutic management of ependymomas with fractionated stereotactic radiotherapy (FSRT). BMC Cancer 2006; 6:222.
    • (2006) BMC Cancer , vol.6 , pp. 222
    • Combs, S.E.1    Thilmann, C.2    Debus, J.3
  • 70
    • 33745952557 scopus 로고    scopus 로고
    • The role of Gamma Knife Radiosurgery in the management of unresectable gross disease or gross residual disease after surgery in ependymoma
    • Lo SS, Abdulrahman R, Desrosiers PM, et al. The role of Gamma Knife Radiosurgery in the management of unresectable gross disease or gross residual disease after surgery in ependymoma. J Neurooncol 2006; 79:51-56.
    • (2006) J Neurooncol , vol.79 , pp. 51-56
    • Lo, S.S.1    Abdulrahman, R.2    Desrosiers, P.M.3
  • 71
    • 0033493761 scopus 로고    scopus 로고
    • Chemotherapy for advanced CNS ependymoma
    • Gornet MK, Buckner JC, et al. Chemotherapy for advanced CNS ependymoma. J Neurooncol 1999; 45:61-67.
    • (1999) J Neurooncol , vol.45 , pp. 61-67
    • Gornet, M.K.1    Buckner, J.C.2
  • 72
    • 20544467924 scopus 로고    scopus 로고
    • A multicenter retrospective study of chemotherapy for recurrent intracranial ependymal tumors in adults by the Gruppo ltaliano Cooperativo di Neuro-Oncologia
    • Brandes AA, Cavallo G, Reni M, et al. A multicenter retrospective study of chemotherapy for recurrent intracranial ependymal tumors in adults by the Gruppo ltaliano Cooperativo di Neuro-Oncologia. Cancer 2005; 104:143-148.
    • (2005) Cancer , vol.104 , pp. 143-148
    • Brandes, A.A.1    Cavallo, G.2    Reni, M.3
  • 73
    • 0141890081 scopus 로고    scopus 로고
    • Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin
    • Rojas-Marcos I, Calvet D, Janoray P, et al. Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin. Neurology 2003; 61:1019-1020.
    • (2003) Neurology , vol.61 , pp. 1019-1020
    • Rojas-Marcos, I.1    Calvet, D.2    Janoray, P.3
  • 74
    • 56749111590 scopus 로고    scopus 로고
    • Chemotherapy of ependymoma
    • Newton HB, editor, London: Academic Press, Elsevier;
    • Malkin MG. Chemotherapy of ependymoma. In: Newton HB, editor. Handbook of brain tumor chemotherapy. London: Academic Press, Elsevier; 2006 pp. 426-431.
    • (2006) Handbook of brain tumor chemotherapy , pp. 426-431
    • Malkin, M.G.1
  • 75
    • 0029011186 scopus 로고
    • Activity of temozolomide in the treatment of central nervous system tumor xenografts
    • Friedman HS, Dolan ME, Pegg AE, et al. Activity of temozolomide in the treatment of central nervous system tumor xenografts. Cancer Res 1995; 55:2853-2857.
    • (1995) Cancer Res , vol.55 , pp. 2853-2857
    • Friedman, H.S.1    Dolan, M.E.2    Pegg, A.E.3
  • 76
    • 33644870901 scopus 로고    scopus 로고
    • A case report of a recurrent intracranial ependymoma treated with temozolomide in remission 10 years after completing chemotherapy
    • Rehman S, Brock C, Newlands ES. A case report of a recurrent intracranial ependymoma treated with temozolomide in remission 10 years after completing chemotherapy. Am J Clin Oncol 2006; 29:106-107.
    • (2006) Am J Clin Oncol , vol.29 , pp. 106-107
    • Rehman, S.1    Brock, C.2    Newlands, E.S.3
  • 77
    • 0010953490 scopus 로고    scopus 로고
    • Response of ependymomas to chemotherapy with temozolomide
    • Rudà R, Costanza A, Nobile M, et al. Response of ependymomas to chemotherapy with temozolomide. J Neurooncol 2001; 3:66.
    • (2001) J Neurooncol , vol.3 , pp. 66
    • Rudà, R.1    Costanza, A.2    Nobile, M.3
  • 79
    • 0025910011 scopus 로고
    • Postoperative radiotherapy in the management of spinal cord ependymoma
    • Whitaker SJ, Bessell EM, Ashley SE, et al. Postoperative radiotherapy in the management of spinal cord ependymoma. J Neurosurg 1991; 74:720-728.
    • (1991) J Neurosurg , vol.74 , pp. 720-728
    • Whitaker, S.J.1    Bessell, E.M.2    Ashley, S.E.3
  • 80
    • 33750309606 scopus 로고    scopus 로고
    • Spinal myxopapillary ependymoma outcomes in patients treated with surgery and radiotherapy at M.D. Anderson Cancer Center
    • Akyurek S, Chang EL, Yu TK, et al. Spinal myxopapillary ependymoma outcomes in patients treated with surgery and radiotherapy at M.D. Anderson Cancer Center. J Neurooncol 2006; 80:177-183.
    • (2006) J Neurooncol , vol.80 , pp. 177-183
    • Akyurek, S.1    Chang, E.L.2    Yu, T.K.3
  • 81
    • 34247194634 scopus 로고    scopus 로고
    • The importance of early postoperative radiation in spinal myxopapillary ependymomas
    • The first report of a CSF spread of a myxopapillary spinal ependymoma as early as six weeks after surgery
    • Dickerman RD, Reynolds AS, Gilbert E, et al. The importance of early postoperative radiation in spinal myxopapillary ependymomas. J Neurooncol 2007; 82:323-325. The first report of a CSF spread of a myxopapillary spinal ependymoma as early as six weeks after surgery.
    • (2007) J Neurooncol , vol.82 , pp. 323-325
    • Dickerman, R.D.1    Reynolds, A.S.2    Gilbert, E.3
  • 82
    • 0033103932 scopus 로고    scopus 로고
    • Extraneural metastasizing ependymoma of the spinal cord
    • Graf M, Blaeker H, Otto HF. Extraneural metastasizing ependymoma of the spinal cord. Pathol Oncol Res 1999; 5:56-60.
    • (1999) Pathol Oncol Res , vol.5 , pp. 56-60
    • Graf, M.1    Blaeker, H.2    Otto, H.F.3
  • 83
    • 23144452287 scopus 로고    scopus 로고
    • High failure rate in spinal ependymomas with long-term follow-up
    • Gomez DR, Missett BT, Wara WM, et al. High failure rate in spinal ependymomas with long-term follow-up. Neuro Oncol 2005; 7:254-259.
    • (2005) Neuro Oncol , vol.7 , pp. 254-259
    • Gomez, D.R.1    Missett, B.T.2    Wara, W.M.3
  • 84
    • 33644514642 scopus 로고    scopus 로고
    • Spinal cord gliomas: A multi-institutional retrospective analysis
    • Abdel-Wahab M, Etuk B, Palermo J, et al. Spinal cord gliomas: a multi-institutional retrospective analysis. Int J Radiat Oncol Biol Phys 2006; 64:1060-1071.
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 1060-1071
    • Abdel-Wahab, M.1    Etuk, B.2    Palermo, J.3
  • 85
    • 0020056712 scopus 로고
    • A comparative study of ependymomas by site of origin
    • Marks JE, Adler SJ. A comparative study of ependymomas by site of origin. Int J Radiat Oncol Biol Phys 1982; 8:37-43.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 37-43
    • Marks, J.E.1    Adler, S.J.2
  • 86
    • 0025892293 scopus 로고
    • The role of radiation therapy in the management of ependymomas of the spinal cord
    • Wen BC, Hussey DH, Hitchon PW, et al. The role of radiation therapy in the management of ependymomas of the spinal cord. Int J Radiat Oncol Biol Phys 1991;20:781-786.
    • (1991) Int J Radiat Oncol Biol Phys , vol.20 , pp. 781-786
    • Wen, B.C.1    Hussey, D.H.2    Hitchon, P.W.3
  • 87
    • 0019430506 scopus 로고
    • Long-term results of the surgical treatment of 129 intramedullary spinal gliomas
    • Guidetti B, Mercuri S, Vagnozzi R. Long-term results of the surgical treatment of 129 intramedullary spinal gliomas. J Neurosurg 1981; 54:323-330.
    • (1981) J Neurosurg , vol.54 , pp. 323-330
    • Guidetti, B.1    Mercuri, S.2    Vagnozzi, R.3
  • 88
    • 0022345654 scopus 로고
    • Radical resection of intramedullary spinal cord tumors in adults. Recent experience in 29 patients
    • Cooper PR, Epstein F. Radical resection of intramedullary spinal cord tumors in adults. Recent experience in 29 patients. J Neurosurg 1985; 63:492-499.
    • (1985) J Neurosurg , vol.63 , pp. 492-499
    • Cooper, P.R.1    Epstein, F.2
  • 89
    • 0025308564 scopus 로고
    • Intramedullary ependymoma of the spinal cord
    • McCormick PC, Torres R, Post KD, et al. Intramedullary ependymoma of the spinal cord. J Neurosurg 1990; 72:523-532.
    • (1990) J Neurosurg , vol.72 , pp. 523-532
    • McCormick, P.C.1    Torres, R.2    Post, K.D.3
  • 90
    • 35449004997 scopus 로고    scopus 로고
    • Outcomes in treatment for intradural spinal cord ependymomas
    • A retrospective study confirming the value of en-bloc gross total resection as initial treatment for spinal cord ependymomas
    • Volpp PB, Han K, Kagan AR, et al. Outcomes in treatment for intradural spinal cord ependymomas. Int J Radiat Oncol Biol Phys 2007; 69:1199-1204. A retrospective study confirming the value of en-bloc gross total resection as initial treatment for spinal cord ependymomas.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 1199-1204
    • Volpp, P.B.1    Han, K.2    Kagan, A.R.3
  • 91
    • 0036870322 scopus 로고    scopus 로고
    • Spinal cord ependymoma: Radical surgical resection and outcome
    • Hanbali F, Fourney DR, Marmor E, et al. Spinal cord ependymoma: radical surgical resection and outcome. Neurosurgery 2002; 51:1162-1172.
    • (2002) Neurosurgery , vol.51 , pp. 1162-1172
    • Hanbali, F.1    Fourney, D.R.2    Marmor, E.3
  • 92
    • 20144369333 scopus 로고    scopus 로고
    • Treatment of spinal cord ependymomas by surgery with or without postoperative radiotherapy
    • Lin YH, Huang CI, Wong TT, et al. Treatment of spinal cord ependymomas by surgery with or without postoperative radiotherapy. J Neurooncol 2005; 71:205-210.
    • (2005) J Neurooncol , vol.71 , pp. 205-210
    • Lin, Y.H.1    Huang, C.I.2    Wong, T.T.3
  • 93
    • 0033828068 scopus 로고    scopus 로고
    • Intramedullary ependymomas: Clinical presentation, surgical treatment strategies and prognosis
    • Schwartz TH, McGormick PC. Intramedullary ependymomas: clinical presentation, surgical treatment strategies and prognosis. J Neurooncol 2000; 47:211-218.
    • (2000) J Neurooncol , vol.47 , pp. 211-218
    • Schwartz, T.H.1    McGormick, P.C.2
  • 94
    • 0024850305 scopus 로고
    • Outcome after operative treatment of intramedullary spinal cord tumors in adults: Intermediate and long-term results in 51 patients
    • Cooper PR. Outcome after operative treatment of intramedullary spinal cord tumors in adults: intermediate and long-term results in 51 patients. Neurosurgery 1989; 25:855-859.
    • (1989) Neurosurgery , vol.25 , pp. 855-859
    • Cooper, P.R.1
  • 95
    • 0022410399 scopus 로고
    • Primary spinal cord tumors treated with surgery and postoperative irradiation
    • Garcia DM. Primary spinal cord tumors treated with surgery and postoperative irradiation. Int J Radiat Oncol Biol Phys 1985; 11:1933-1939.
    • (1985) Int J Radiat Oncol Biol Phys , vol.11 , pp. 1933-1939
    • Garcia, D.M.1
  • 98
    • 0030465613 scopus 로고    scopus 로고
    • Spinal ependymomas: The value of postoperative radiotherapy for residual disease control
    • Sgouros S, Malluci CL, Jackowski A. Spinal ependymomas: the value of postoperative radiotherapy for residual disease control. Br J Neurosurg 1996; 10:559-566.
    • (1996) Br J Neurosurg , vol.10 , pp. 559-566
    • Sgouros, S.1    Malluci, C.L.2    Jackowski, A.3
  • 99
    • 34247538495 scopus 로고    scopus 로고
    • Long term outcome with postoperative radiation therapy for spinal canal ependymoma
    • A retrospective study evaluating the long term efficacy and safety of postoperative radiation therapy in the managment of spinal canal ependymoma
    • Wahab SH, Simpson JR, Michalski JM, et al. Long term outcome with postoperative radiation therapy for spinal canal ependymoma. J Neurooncol 2007; 83:85-89. A retrospective study evaluating the long term efficacy and safety of postoperative radiation therapy in the managment of spinal canal ependymoma.
    • (2007) J Neurooncol , vol.83 , pp. 85-89
    • Wahab, S.H.1    Simpson, J.R.2    Michalski, J.M.3
  • 101
    • 0018111709 scopus 로고
    • Radiation therapy of malignant brain tumors
    • Wara WM, Sheline GE. Radiation therapy of malignant brain tumors. Clin Neurosurg 1978; 25:397-402.
    • (1978) Clin Neurosurg , vol.25 , pp. 397-402
    • Wara, W.M.1    Sheline, G.E.2
  • 104
    • 4243703294 scopus 로고    scopus 로고
    • Chemotherapeutic treatment of ependymomas ar Memorial Sloan-Kettering Cancer Center from 1994 to 2000
    • Begemann M, De Angelis LM. Chemotherapeutic treatment of ependymomas ar Memorial Sloan-Kettering Cancer Center from 1994 to 2000. Proc Am Soc Clin Oncol 2001; 20:65a-258a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Begemann, M.1    De Angelis, L.M.2
  • 105
    • 0036721203 scopus 로고    scopus 로고
    • Salvage chemotherapy for recurrent spinal cord ependymona
    • Chamberlain MC. Salvage chemotherapy for recurrent spinal cord ependymona. Cancer 2002; 95:997-1002.
    • (2002) Cancer , vol.95 , pp. 997-1002
    • Chamberlain, M.C.1
  • 106
    • 8744272196 scopus 로고    scopus 로고
    • Recurrent spinal ependymoma showing partial remission under imatimib
    • Fakhrai N, Neophytou P, Dieckmann K, et al. Recurrent spinal ependymoma showing partial remission under imatimib. Acta Neurochir 2004; 146:1255-1258.
    • (2004) Acta Neurochir , vol.146 , pp. 1255-1258
    • Fakhrai, N.1    Neophytou, P.2    Dieckmann, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.