Molecular genetic alterations on chromosomes 11 and 22 in ependymomas

International Journal of Cancer

Volumn 91, Issue 6, 2001, Pages 803-808

  Lamszus, Katrin ^a   Lachenmayer, Lenard ^a   Heinemann, Uta ^a   Kluwe, Lan ^a   Finckh, Ulrich ^a   Höppner, Wolfgang ^b   Stavrou, Dimitrios ^a   Fillbrandt, Regina ^a   Westphal, Manfred ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Ependymal tumor; Loss of heterozygosity; Multiple endocrine neoplasia type 1; Mutation; Neurofibromatosis 2

Indexed keywords

ALLELE; ARTICLE; CANCER GRADING; CHROMOSOME 11; CHROMOSOME 22; EPENDYMOMA; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MOLECULAR GENETICS; MULTIPLE ENDOCRINE NEOPLASIA; PRIORITY JOURNAL; TUMOR LOCALIZATION;

ADOLESCENT; ADULT; AGED; ALLELES; BASE SEQUENCE; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 22; DNA PRIMERS; EPENDYMOMA; FEMALE; GENES, NEUROFIBROMATOSIS 2; HUMANS; INFANT; INFANT, NEWBORN; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; SEQUENCE ANALYSIS, DNA; SPINAL CORD NEOPLASMS;

EID: 0035869674     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(200002)9999:9999<::AID-IJC1134>3.0.CO;2-P     Document Type: Article

References (40)

1. The molecular biology of ependymomas
2. Ependymal tumours
3. Posterior fossa ependymomas: Report of 30 cases and review of the literature
4. Ependymoma: A follow-up study of 101 cases
5. A cytogenetic study of 53 human gliomas
6. Cytogenetic abnormalities in human ependymomas
7. Cytogenetics of human brain tumors
8. Cytogenetic and loss of heterozygosity studies in ependymomas, pilocytic astrocytomas, and oligodendrogliomas
9. Cytogenetic t(11;17)(q13;q21) in a pediatric ependymoma
10. Molecular analysis of genetic changes in ependymomas
11. Molecular genetic analysis of chromosome arm 17p and chromosome arm 22q DNA sequences in sporadic pediatric ependymomas
12. Molecular genetic analysis of ependymal tumors: NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas
13. The natural history of multiple endocrine neoplasia type 1: Highly uncommon or highly unrecognized
14. Multiple endocrine neoplasia type 1 associated with spinal ependymoma
15. A large multiple endocrine neoplasia type 1 family with clinical expression suggestive of anticipation
16. Interphase cytogenetics: A new tool for the study of genetic changes in brain tumors
17. Cytogenetic evidence for a chromosome 22 tumor suppressor gene in ependymoma
18. Chromosome aberrations in four ependymomas
19. Involvement of chromosome 22 in ependymomas
20. Cytogenetic findings in a supratentorial ependymoma
21. Cytogenetic analysis of 109 pediatric central nervous system tumors
22. Allelic losses at 1p, 9q, 10q, 14q, and 22q in the progression of aggressive meningiomas and undifferentiated meningeal sarcomas
23. Allelic losses in neurofibromatosis 2-associated meningiomas
24. A microsatelite-based index map of human chromosome 11
25. Deletion mapping of endocrine tumors localizes a second tumor suppressor gene on chromosome band 11q13
26. Mutation nomenclature extensions and suggestions to describe complex mutations: A discussion
27. Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states
28. Positional cloning of the gene for multiple endocrine neoplasia-type 1
29. Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders
30. Multiple endocrine neoplasia type 1 (MEN1): Clinical heterogeneity in a large family with a nonsense mutation in the MEN1 gene (Trp471Stop)
31. Menin interacts with the AP1 transcription factor JunD and represses JunD-acfivated transcription
32. Loss of heterozygosity in squamous cell carcinomas of the head and neck defines a tumor suppressor gene region on 11q13
33. Identification and mutation analysis of DOC-1R, a DOC-1 growth suppressor-related gene
34. Analysis of the neurofibromatosis 2 gene in human ependymomas and astrocytomas
35. Exon scanning for mutations of the NF2 gene in pediatric ependymomas, rhabdoid tumors and meningiomas
36. Analysis of the neurofibromatosis type 2 gene in different human tumors of neuroectodermal origin
37. Frequent type 2 neurofibromatosis gene transcript mutations in sporadic intramedullary spinal cord ependymomas
38. Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter-22q11.2
39. Molecular studies of an ependymoma-associated constitutional t (1;22) (p22;q11.2)
40. Familial anaplastic ependymoma: Evidence of loss of chromosome 22 in tumour cells