메뉴 건너뛰기




Volumn 47, Issue 12, 2008, Pages 1780-1784

C-reactive protein: The underlying cause of microvascular dysfunction in rheumatoid arthritis

Author keywords

C reactive protein; Cardiovascular disease; Endothelium; Inflammation; Microcirculation; Rheumatoid arthritis

Indexed keywords

ACETYLCHOLINE; ADALIMUMAB; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DISEASE MODIFYING ANTIRHEUMATIC DRUG; DIURETIC AGENT; ETANERCEPT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INFLIXIMAB; METHOTREXATE; MOXONIDINE; NITROPRUSSIDE SODIUM; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

EID: 56649091431     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken386     Document Type: Article
Times cited : (67)

References (48)
  • 2
    • 0028941806 scopus 로고
    • Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis
    • Myllykangas-Luosujarvi R, Aho K, Kautiainen H, Isomaki H. Shortening of life span and causes of excess mortality in a population-based series of subjects with rheumatoid arthritis. Clin Exp Rheumatol 1995;13:149-53.
    • (1995) Clin Exp Rheumatol , vol.13 , pp. 149-153
    • Myllykangas-Luosujarvi, R.1    Aho, K.2    Kautiainen, H.3    Isomaki, H.4
  • 4
    • 34548276566 scopus 로고    scopus 로고
    • Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis
    • Panoulas VF, Douglas KM, Milionis HJ et al. Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis. Rheumatology 2007;46:1477-82.
    • (2007) Rheumatology , vol.46 , pp. 1477-1482
    • Panoulas, V.F.1    Douglas, K.M.2    Milionis, H.J.3
  • 5
    • 0008856783 scopus 로고    scopus 로고
    • Lipid profiles in untreated patients with rheumatoid arthritis
    • Park YB, Lee SK, Lee WK et al. Lipid profiles in untreated patients with rheumatoid arthritis. J Rheumatol 1999;26:1701-4.
    • (1999) J Rheumatol , vol.26 , pp. 1701-1704
    • Park, Y.B.1    Lee, S.K.2    Lee, W.K.3
  • 6
    • 0035676529 scopus 로고    scopus 로고
    • High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors
    • del Rincon ID, Williams K, Stern MP, Freeman GL, Escalante A. High incidence of cardiovascular events in a rheumatoid arthritis cohort not explained by traditional cardiac risk factors. Arthritis Rheum 2001;44:2737-45.
    • (2001) Arthritis Rheum , vol.44 , pp. 2737-2745
    • del Rincon, I.D.1    Williams, K.2    Stern, M.P.3    Freeman, G.L.4    Escalante, A.5
  • 7
    • 0033598672 scopus 로고    scopus 로고
    • A tale of two diseases: Atherosclerosis and rheumatoid arthritis
    • Pasceri V, Yeh ET. A tale of two diseases: Atherosclerosis and rheumatoid arthritis. Circulation 1999;100:2124-6.
    • (1999) Circulation , vol.100 , pp. 2124-2126
    • Pasceri, V.1    Yeh, E.T.2
  • 8
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002;420:868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 9
    • 0026478022 scopus 로고
    • Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
    • Celermajer DS, Sorensen KE, Gooch VM et al. Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340:1111-5.
    • (1992) Lancet , vol.340 , pp. 1111-1115
    • Celermajer, D.S.1    Sorensen, K.E.2    Gooch, V.M.3
  • 10
    • 0141634198 scopus 로고    scopus 로고
    • Impaired microvascular function in normal children: Effects of adiposity and poor glucose handling
    • Khan F, Green FC, Forsyth JS, Greene SA, Morris AD, Belch JJ. Impaired microvascular function in normal children: Effects of adiposity and poor glucose handling. J Physiol 2003;551:705-11.
    • (2003) J Physiol , vol.551 , pp. 705-711
    • Khan, F.1    Green, F.C.2    Forsyth, J.S.3    Greene, S.A.4    Morris, A.D.5    Belch, J.J.6
  • 11
    • 0037159293 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis
    • Hurlimann D, Forster A, Noll G et al. Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis. Circulation 2002;106:2184-7.
    • (2002) Circulation , vol.106 , pp. 2184-2187
    • Hurlimann, D.1    Forster, A.2    Noll, G.3
  • 12
    • 34250316501 scopus 로고    scopus 로고
    • Forearm haemodynamics, arterial stiffness and microcirculatory reactivity in rheumatoid arthritis
    • Arosio E, De Marchi S, Rigoni A, Prior M, Delva P, Lechi A. Forearm haemodynamics, arterial stiffness and microcirculatory reactivity in rheumatoid arthritis. J Hypertens 2007;25:1273-8.
    • (2007) J Hypertens , vol.25 , pp. 1273-1278
    • Arosio, E.1    De Marchi, S.2    Rigoni, A.3    Prior, M.4    Delva, P.5    Lechi, A.6
  • 13
    • 9144252008 scopus 로고    scopus 로고
    • Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity
    • Vaudo G, Marchesi S, Gerli R et al. Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity. Ann Rheum Dis 2004;63:31-5.
    • (2004) Ann Rheum Dis , vol.63 , pp. 31-35
    • Vaudo, G.1    Marchesi, S.2    Gerli, R.3
  • 14
    • 0033980447 scopus 로고    scopus 로고
    • Impaired skin microvascular function in children, adolescents, and young adults with type 1 diabetes
    • Khan F, Elhadd TA, Greene SA, Belch JJ. Impaired skin microvascular function in children, adolescents, and young adults with type 1 diabetes. Diabetes care 2000;23:215-20.
    • (2000) Diabetes care , vol.23 , pp. 215-220
    • Khan, F.1    Elhadd, T.A.2    Greene, S.A.3    Belch, J.J.4
  • 15
    • 1242351319 scopus 로고    scopus 로고
    • Non-invasive assessment of microvascular endothelial function by laser Doppler flowmetry in patients with essential hypertension
    • Farkas K, Kolossvary E, Jarai Z, Nemcsik J, Farsang C. Non-invasive assessment of microvascular endothelial function by laser Doppler flowmetry in patients with essential hypertension. Atherosclerosis 2004;173:97-102.
    • (2004) Atherosclerosis , vol.173 , pp. 97-102
    • Farkas, K.1    Kolossvary, E.2    Jarai, Z.3    Nemcsik, J.4    Farsang, C.5
  • 16
    • 0032726506 scopus 로고    scopus 로고
    • Skin blood flow in patients with systemic sclerosis and Raynaud's phenomenon: Effects of oral L-arginine supplementation
    • Khan F, Belch JJ. Skin blood flow in patients with systemic sclerosis and Raynaud's phenomenon: Effects of oral L-arginine supplementation. J Rheumatol 1999;26:2389-94.
    • (1999) J Rheumatol , vol.26 , pp. 2389-2394
    • Khan, F.1    Belch, J.J.2
  • 17
    • 0037789568 scopus 로고    scopus 로고
    • Individuals at increased coronary heart disease risk are characterized by an impaired microvascular function in skin
    • Ijzerman RG, de Jongh RT, Beijk MA et al. Individuals at increased coronary heart disease risk are characterized by an impaired microvascular function in skin. Eur J Clin Investig 2003;33:536-42.
    • (2003) Eur J Clin Investig , vol.33 , pp. 536-542
    • Ijzerman, R.G.1    de Jongh, R.T.2    Beijk, M.A.3
  • 18
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
    • (1988) Arthritis Rheum , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3
  • 19
    • 0028815803 scopus 로고
    • Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis
    • Prevoo ML, van't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44-8.
    • (1995) Arthritis Rheum , vol.38 , pp. 44-48
    • Prevoo, M.L.1    van't Hof, M.A.2    Kuper, H.H.3    van Leeuwen, M.A.4    van de Putte, L.B.5    van Riel, P.L.6
  • 20
    • 0024803452 scopus 로고
    • Discriminant and convergent validity of self-report measures of affective distress in patients with rheumatoid arthritis
    • Hagglund KJ, Roth DL, Haley WE, Alarcon GS. Discriminant and convergent validity of self-report measures of affective distress in patients with rheumatoid arthritis. J Rheumatol 1989;16:1428-32.
    • (1989) J Rheumatol , vol.16 , pp. 1428-1432
    • Hagglund, K.J.1    Roth, D.L.2    Haley, W.E.3    Alarcon, G.S.4
  • 21
    • 0034659135 scopus 로고    scopus 로고
    • Enhanced sensitivity of the peripheral cholinergic vascular response in patients with chronic fatigue syndrome
    • Spence VA, Khan F, Belch JJ. Enhanced sensitivity of the peripheral cholinergic vascular response in patients with chronic fatigue syndrome. Am J Med 2000;108:736-9.
    • (2000) Am J Med , vol.108 , pp. 736-739
    • Spence, V.A.1    Khan, F.2    Belch, J.J.3
  • 22
    • 0035214964 scopus 로고    scopus 로고
    • Assessment of microvascular endothelial function in human skin
    • Newton DJ, Khan F, Belch JJ. Assessment of microvascular endothelial function in human skin. Clin Sci 2001;101:567-72.
    • (2001) Clin Sci , vol.101 , pp. 567-572
    • Newton, D.J.1    Khan, F.2    Belch, J.J.3
  • 23
    • 0028793753 scopus 로고
    • Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM
    • Morris SJ, Shore AC, Tooke JE. Responses of the skin microcirculation to acetylcholine and sodium nitroprusside in patients with NIDDM. Diabetologia 1995;38:1337-44.
    • (1995) Diabetologia , vol.38 , pp. 1337-1344
    • Morris, S.J.1    Shore, A.C.2    Tooke, J.E.3
  • 24
    • 33748644710 scopus 로고    scopus 로고
    • Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapy
    • Maki-Petaja KM, Hall FC, Booth AD et al. Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by anti-tumor necrosis factor-alpha therapy. Circulation 2006;114:1185-92.
    • (2006) Circulation , vol.114 , pp. 1185-1192
    • Maki-Petaja, K.M.1    Hall, F.C.2    Booth, A.D.3
  • 25
    • 0033759447 scopus 로고    scopus 로고
    • Reproducibility of laser Doppler imaging of skin blood flow as a tool to assess endothelial function
    • Kubli S, Waeber B, Dalle-Ave A, Feihl F. Reproducibility of laser Doppler imaging of skin blood flow as a tool to assess endothelial function. J Cardiovasc Pharmacol 2000;36:640-8.
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 640-648
    • Kubli, S.1    Waeber, B.2    Dalle-Ave, A.3    Feihl, F.4
  • 26
    • 0023028215 scopus 로고
    • Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries
    • Ludmer PL, Selwyn AP, Shook TL et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 1986; 315:1046-51.
    • (1986) N Engl J Med , vol.315 , pp. 1046-1051
    • Ludmer, P.L.1    Selwyn, A.P.2    Shook, T.L.3
  • 27
    • 0025008831 scopus 로고
    • Responses of angiographically normal human coronary arteries to intracoronary injection of acetylcholine by age and segment. Possible role of early coronary atherosclerosis
    • Yasue H, Matsuyama K, Matsuyama K, Okumura K, Morikami Y, Ogawa H. Responses of angiographically normal human coronary arteries to intracoronary injection of acetylcholine by age and segment. Possible role of early coronary atherosclerosis. Circulation 1990;81:482-90.
    • (1990) Circulation , vol.81 , pp. 482-490
    • Yasue, H.1    Matsuyama, K.2    Matsuyama, K.3    Okumura, K.4    Morikami, Y.5    Ogawa, H.6
  • 28
    • 0028784709 scopus 로고
    • Close relation of endothelial function in the human coronary and peripheral circulations
    • Anderson TJ, Uehata A, Gerhard MD et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 1995; 26:1235-41.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1235-1241
    • Anderson, T.J.1    Uehata, A.2    Gerhard, M.D.3
  • 29
    • 8844256604 scopus 로고    scopus 로고
    • Non-invasive assessment of endothelial function - relation between vasodilatory responses in skin microcirculation and brachial artery
    • Hansell J, Henareh L, Agewall S, Norman M. Non-invasive assessment of endothelial function - relation between vasodilatory responses in skin microcirculation and brachial artery. Clin Physiol Funct Imaging 2004;24:317-22.
    • (2004) Clin Physiol Funct Imaging , vol.24 , pp. 317-322
    • Hansell, J.1    Henareh, L.2    Agewall, S.3    Norman, M.4
  • 30
    • 35148828893 scopus 로고    scopus 로고
    • Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery
    • Huang AL, Silver AE, Shvenke E et al. Predictive value of reactive hyperemia for cardiovascular events in patients with peripheral arterial disease undergoing vascular surgery. Arterioscler Thromb Vasc Biol 2007;27:2113-9.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2113-2119
    • Huang, A.L.1    Silver, A.E.2    Shvenke, E.3
  • 31
    • 3543022093 scopus 로고    scopus 로고
    • Local shear stress and brachial artery flowmediated dilation: The Framingham Heart Study
    • Mitchell GF, Parise H, Vita JA et al. Local shear stress and brachial artery flowmediated dilation: The Framingham Heart Study. Hypertension 2004;44:134-9.
    • (2004) Hypertension , vol.44 , pp. 134-139
    • Mitchell, G.F.1    Parise, H.2    Vita, J.A.3
  • 33
    • 28444457810 scopus 로고    scopus 로고
    • Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis
    • Dessein PH, Joffe BI, Singh S. Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Arthritis Res Ther 2005;7:R634-43.
    • (2005) Arthritis Res Ther , vol.7
    • Dessein, P.H.1    Joffe, B.I.2    Singh, S.3
  • 34
    • 0027185328 scopus 로고
    • Abnormal plasma fibrinolysis in patients with rheumatoid arthritis and impaired endothelial fibrinolytic response in those complicated by vasculitis
    • Lau CS, McLaren M, Hanslip J, Kerr M, Belch JJ. Abnormal plasma fibrinolysis in patients with rheumatoid arthritis and impaired endothelial fibrinolytic response in those complicated by vasculitis. Ann Rheum Dis 1993;52:643-9.
    • (1993) Ann Rheum Dis , vol.52 , pp. 643-649
    • Lau, C.S.1    McLaren, M.2    Hanslip, J.3    Kerr, M.4    Belch, J.J.5
  • 35
    • 0031693285 scopus 로고    scopus 로고
    • Soluble cell adhesion molecules-P-selectin and ICAM-1, and disease activity in patients receiving sulphasalazine for active rheumatoid arthritis
    • Veale DJ, Maple C, Kirk G, McLaren M, Belch JJ. Soluble cell adhesion molecules-P-selectin and ICAM-1, and disease activity in patients receiving sulphasalazine for active rheumatoid arthritis. Scand J Rheumatol 1998;27:296-9.
    • (1998) Scand J Rheumatol , vol.27 , pp. 296-299
    • Veale, D.J.1    Maple, C.2    Kirk, G.3    McLaren, M.4    Belch, J.J.5
  • 36
    • 34248156709 scopus 로고    scopus 로고
    • Inflammatory suppression rapidly attenuates microvascular dysfunction in rheumatoid arthritis
    • Datta D, Ferrell WR, Sturrock RD, Jadhav ST, Sattar N. Inflammatory suppression rapidly attenuates microvascular dysfunction in rheumatoid arthritis. Atherosclerosis 2006;192:391-5.
    • (2006) Atherosclerosis , vol.192 , pp. 391-395
    • Datta, D.1    Ferrell, W.R.2    Sturrock, R.D.3    Jadhav, S.T.4    Sattar, N.5
  • 37
    • 0030956673 scopus 로고    scopus 로고
    • Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
    • Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997;336:973-9.
    • (1997) N Engl J Med , vol.336 , pp. 973-979
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3    Tracy, R.P.4    Hennekens, C.H.5
  • 38
    • 0348110529 scopus 로고    scopus 로고
    • Endothelial function, inflammation, and prognosis in cardiovascular disease
    • Gonzalez MA, Selwyn AP. Endothelial function, inflammation, and prognosis in cardiovascular disease. Am J Med 2003;115(Suppl. 8A):99S-106S.
    • (2003) Am J Med , vol.115 , Issue.SUPPL. 8A
    • Gonzalez, M.A.1    Selwyn, A.P.2
  • 39
    • 0027933081 scopus 로고
    • The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina
    • Liuzzo G, Biasucci LM, Gallimore JR et al. The prognostic value of C-reactive protein and serum amyloid a protein in severe unstable angina. N Engl J Med 1994;331:417-24.
    • (1994) N Engl J Med , vol.331 , pp. 417-424
    • Liuzzo, G.1    Biasucci, L.M.2    Gallimore, J.R.3
  • 40
    • 23644453158 scopus 로고    scopus 로고
    • Baseline levels of C-reactive protein and prediction of death from cardiovascular disease in patients with inflammatory polyarthritis: A ten-year followup study of a primary care-based inception cohort
    • Goodson NJ, Symmons DP, Scott DG, Bunn D, Lunt M, Silman AJ. Baseline levels of C-reactive protein and prediction of death from cardiovascular disease in patients with inflammatory polyarthritis: A ten-year followup study of a primary care-based inception cohort. Arthritis Rheum 2005;52:2293-9.
    • (2005) Arthritis Rheum , vol.52 , pp. 2293-2299
    • Goodson, N.J.1    Symmons, D.P.2    Scott, D.G.3    Bunn, D.4    Lunt, M.5    Silman, A.J.6
  • 41
    • 22244456685 scopus 로고    scopus 로고
    • High-grade C-reactive protein elevation correlates with accelerated atherogenesis in patients with rheumatoid arthritis
    • Gonzalez-Gay MA, Gonzalez-Juanatey C, Pineiro A, Garcia-Porrua C, Testa A, Llorca J. High-grade C-reactive protein elevation correlates with accelerated atherogenesis in patients with rheumatoid arthritis. J Rheumatol 2005;32:1219-23.
    • (2005) J Rheumatol , vol.32 , pp. 1219-1223
    • Gonzalez-Gay, M.A.1    Gonzalez-Juanatey, C.2    Pineiro, A.3    Garcia-Porrua, C.4    Testa, A.5    Llorca, J.6
  • 42
    • 1242275127 scopus 로고    scopus 로고
    • Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen
    • Brodsky SV, Gealekman O, Chen J et al. Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen. Circ Res 2004;94:377-84.
    • (2004) Circ Res , vol.94 , pp. 377-384
    • Brodsky, S.V.1    Gealekman, O.2    Chen, J.3
  • 43
    • 0242636458 scopus 로고    scopus 로고
    • C-reactive protein and cardiovascular disease: New insights from an old molecule
    • Hirschfield GM, Pepys MB. C-reactive protein and cardiovascular disease: new insights from an old molecule. Q J Med 2003;96:793-807.
    • (2003) Q J Med , vol.96 , pp. 793-807
    • Hirschfield, G.M.1    Pepys, M.B.2
  • 44
    • 28844475044 scopus 로고    scopus 로고
    • The novel role of C-reactive protein in cardiovascular disease: Risk marker or pathogen
    • Wilson AM, Ryan MC, Boyle AJ. The novel role of C-reactive protein in cardiovascular disease: Risk marker or pathogen. Int J Cardiol 2006;106:291-7.
    • (2006) Int J Cardiol , vol.106 , pp. 291-297
    • Wilson, A.M.1    Ryan, M.C.2    Boyle, A.J.3
  • 45
    • 36849083659 scopus 로고    scopus 로고
    • Disease activity score-28 values differ considerably depending on patient's pain perception and sex
    • Leeb BF, Haindl PM, Maktari A, Nothnagl T, Rintelen B. Disease activity score-28 values differ considerably depending on patient's pain perception and sex. J Rheumatol 2007;34:2382-7.
    • (2007) J Rheumatol , vol.34 , pp. 2382-2387
    • Leeb, B.F.1    Haindl, P.M.2    Maktari, A.3    Nothnagl, T.4    Rintelen, B.5
  • 46
    • 26244448634 scopus 로고    scopus 로고
    • Cardiovascular admissions and mortality in an inception cohort of patients with rheumatoid arthritis with onset in the 1980s and 1990s
    • Goodson N, Marks J, Lunt M, Symmons D. Cardiovascular admissions and mortality in an inception cohort of patients with rheumatoid arthritis with onset in the 1980s and 1990s. Ann Rheum Dis 2005;64:1595-601.
    • (2005) Ann Rheum Dis , vol.64 , pp. 1595-1601
    • Goodson, N.1    Marks, J.2    Lunt, M.3    Symmons, D.4
  • 47
    • 0036675108 scopus 로고    scopus 로고
    • Mortality in early inflammatory polyarthritis: Cardiovascular mortality is increased in seropositive patients
    • Goodson NJ, Wiles NJ, Lunt M, Barrett EM, Silman AJ, Symmons DP. Mortality in early inflammatory polyarthritis: Cardiovascular mortality is increased in seropositive patients. Arthritis Rheum 2002;46:2010-9.
    • (2002) Arthritis Rheum , vol.46 , pp. 2010-2019
    • Goodson, N.J.1    Wiles, N.J.2    Lunt, M.3    Barrett, E.M.4    Silman, A.J.5    Symmons, D.P.6
  • 48
    • 0037029418 scopus 로고    scopus 로고
    • Methotrexate and mortality in patients with rheumatoid arthritis: A prospective study
    • Choi HK, Hernan MA, Seeger JD, Robins JM, Wolfe F. Methotrexate and mortality in patients with rheumatoid arthritis: A prospective study. Lancet 2002;359:1173-7.
    • (2002) Lancet , vol.359 , pp. 1173-1177
    • Choi, H.K.1    Hernan, M.A.2    Seeger, J.D.3    Robins, J.M.4    Wolfe, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.