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Volumn 22, Issue 17, 2008, Pages 2393-2395

Potential limitation of CCR5 antagonists: Drug resistance more often linked to CXCR4-utilizing than to CCR5-utilizine HIV-1

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CHEMOKINE RECEPTOR CXCR4; MARAVIROC; NUCLEOSIDE ANALOG; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 56549122073     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328312c72c     Document Type: Article
Times cited : (10)

References (9)
  • 1
    • 34249089383 scopus 로고    scopus 로고
    • Efficacy and safety of maraviroc plus optimized background therapy in viremic art-experienced patients infected with CCR%-tropic HIV-1: 24-week results of a phase 2b/3 study in US and Canada
    • Los Angeles, California, USA;
    • Lalezari J, Goodrich J, DeJesus E, Lampiris H, Gulick R, Saag M, et al. Efficacy and safety of maraviroc plus optimized background therapy in viremic art-experienced patients infected with CCR%-tropic HIV-1: 24-week results of a phase 2b/3 study in US and Canada. In: 14th Conference on Retroviruses and Opportunistic Infections. Los Angeles, California, USA; 2007.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Lalezari, J.1    Goodrich, J.2    DeJesus, E.3    Lampiris, H.4    Gulick, R.5    Saag, M.6
  • 2
    • 34249075565 scopus 로고    scopus 로고
    • Efficacy and Safety of maraviroc plus optimized background therapy in viremic, ART-experienced patients infected with CCR5-tropic HIV-1 in Europe, Australia, and North America: 24-week results
    • Los Angeles, California, USA;
    • Nelson M, Fatkenheuer G, Konourina I, Lazzarin A, Clumeck N, Horban A, et al. Efficacy and Safety of maraviroc plus optimized background therapy in viremic, ART-experienced patients infected with CCR5-tropic HIV-1 in Europe, Australia, and North America: 24-week results. In: 14th Conference on Retroviruses and Opportunistic Infections. Los Angeles, California, USA; 2007.
    • (2007) 14th Conference on Retroviruses and Opportunistic Infections
    • Nelson, M.1    Fatkenheuer, G.2    Konourina, I.3    Lazzarin, A.4    Clumeck, N.5    Horban, A.6
  • 3
    • 33646443202 scopus 로고    scopus 로고
    • Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4-using virus reservoir
    • Westby M, Lewis M, Whitcomb J, Youle Mike, Pozniak AL, James IT, et al. Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4-using virus reservoir. J Virol 2006; 80:4909-4920.
    • (2006) J Virol , vol.80 , pp. 4909-4920
    • Westby, M.1    Lewis, M.2    Whitcomb, J.3    Mike, Y.4    Pozniak, A.L.5    James, I.T.6
  • 4
    • 0038371316 scopus 로고    scopus 로고
    • Multiple viral genetic analyses detecting low-level HIV-1 replication during effective HAART
    • Frenkel LM, Wang Y, Learn GH, McKernan JL, Ellis GM, Mohan KM, et al. Multiple viral genetic analyses detecting low-level HIV-1 replication during effective HAART. J Virol 2003; 77:5721-5730.
    • (2003) J Virol , vol.77 , pp. 5721-5730
    • Frenkel, L.M.1    Wang, Y.2    Learn, G.H.3    McKernan, J.L.4    Ellis, G.M.5    Mohan, K.M.6
  • 5
    • 22544461340 scopus 로고    scopus 로고
    • Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: Expression of archival virus and replication of virus
    • Tobin NH, Learn GH, Holte SE, Wang Y, Melvin AJ, McKernan JL, et al. Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus. J Virol 2005; 79:9625-9634.
    • (2005) J Virol , vol.79 , pp. 9625-9634
    • Tobin, N.H.1    Learn, G.H.2    Holte, S.E.3    Wang, Y.4    Melvin, A.J.5    McKernan, J.L.6
  • 9
    • 0038637409 scopus 로고    scopus 로고
    • Predicting HIV-1 coreceptor usage with sequence analysis
    • Jensen MA, van 't Wout AB. Predicting HIV-1 coreceptor usage with sequence analysis. AIDS Rev 2003; 5:104-112.
    • (2003) AIDS Rev , vol.5 , pp. 104-112
    • Jensen, M.A.1    van 't Wout, A.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.