Improved conjugation and purification strategies for the preparation of protein-polysaccharide conjugates

Journal of Chromatography A

Volumn 1213, Issue 2, 2008, Pages 169-175

  Suarez N ^a   Massaldi, H ^a   Franco Fraguas, L ^b   Ferreira, F ^a  

^a Universidad de la Republica Instituto de Higiene   (Uruguay)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Capsular polysaccharide; Conjugate antigen; Hydrophobic chromatography; Streptococcus pneumoniae strain 14

Indexed keywords

BODY FLUIDS; ION EXCHANGE; MAMMALS; PROTEINS; PURIFICATION; T-CELLS;

ACTIVATION TECHNIQUES; BOVINE SERUM ALBUMINS; CAPSULAR POLYSACCHARIDES; CONJUGATE ANTIGEN; RESIDUAL CONTAMINANTS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PNEUMONIAE STRAIN 14; TETRAFLUOROBORATES;

HYDROPHOBIC CHROMATOGRAPHY;

1 CYANO 4 DIMETHYLAMINOPYRIDINIUM TETRAFLUOROBORATE; ANTIBODY CONJUGATE; BORIC ACID; BOVINE SERUM ALBUMIN; SEPHADEX; STREPTOCOCCUS PNEUMONIAE SEROTYPE 14 CAPSULAR POLYSACCHARIDE PLUS BOVINE SERUM ALBUMIN CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIUM CONTAMINATION; CONTROLLED STUDY; DRUG CONJUGATION; DRUG PURIFICATION; FEMALE; GEL PERMEATION CHROMATOGRAPHY; IMMUNOBIOLOGY; IMMUNOGENICITY; MOLECULAR STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; T LYMPHOCYTE;

BOVINAE; MUS; STREPTOCOCCUS PNEUMONIAE;

EID: 56549090896     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.10.030     Document Type: Article

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