An adenosine A2A antagonist injected in the NTS reverses thermal prolongation of the LCR in decerebrate piglets

Respiratory Physiology and Neurobiology

Volumn 164, Issue 3, 2008, Pages 358-365

  Xia, Luxi ^a   Bartlett Jr , Donald ^a   Leiter, J C ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Adenosine; Hyperthermia; Laryngeal chemoreflex; Nucleus of the solitary tract; SIDS

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR ANTAGONIST; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; DECEREBRATION; FEMALE; INJECTION; LARYNX; MALE; NERVE CONDUCTION; NEWBORN; NONHUMAN; PHRENIC NERVE; PIGLET; PRIORITY JOURNAL; SOLITARY TRACT NUCLEUS;

ANALYSIS OF VARIANCE; ANIMALS; BODY TEMPERATURE; DECEREBRATE STATE; FEMALE; FEVER; LARYNX; MALE; NEUROPROTECTIVE AGENTS; PYRIMIDINES; REFLEX; SOLITARY NUCLEUS; SWINE; TEMPERATURE; TRIAZOLES;

EID: 56449110810     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2008.08.002     Document Type: Article

References (51)

1. 2A receptors enhances superior laryngeal nerve stimulation-induced apnea in piglets via a GABAergic pathway. J. Appl. Physiol. 103 (2007) 1205-1211
2. Abu-Shaweesh J.M., Dreshaj I.A., Haxhiu M.A., and Martin R.J. Central GABAergic mechanisms are involved in apnea induced by SLN stimulation in piglets. J. Appl. Physiol. 90 (2001) 1570-1576
3. Bandroft J.D., and Cook H.C. The central and peripheral nervous system. In: Bandroft J.D. (Ed). Manual of Histological Techniques and Their Diagnostic Application (1994), Churchill Livingstone, New York 350-351
4. Blanco C. Role of the brain stem in the changes at birth: initiation of continuous breathing and its maintenance. In: Hanson M.A. (Ed). The Fetal and Neonatal Brain Stem (1991), Cambridge University Press, Cambridge
5. Boggs D.F., and Bartlett Jr. D. Chemical specificity of a laryngeal apneic reflex in puppies. J. Appl. Physiol. 53 (1982) 455-462
6. Böhm I., Xia L., Leiter J.C., and Bartlett Jr. D. GABAergic processes mediate thermal prolongation of laryngeal reflex apnea in decerebrate piglets. Respir. Physiol. Neurobiol. 156 (2007) 229-233
7. Curran A.K., Xia L., Leiter J.C., and Bartlett Jr. D. Elevated body temperature enhances the laryngeal chemoreflex in decerebrate piglets. J. Appl. Physiol. 98 (2005) 780-786
8. Czyzyk-Krzeska M.F., and Lawson E.E. Synaptic events in ventral respiratory neurones during apnoea induced by laryngeal nerve stimulation in neonatal piglet. J. Physiol. 436 (1991) 131-147
9. Daily W.J., Klaus M.H., and Meyer H.B. Apnea in premature infants: monitoring, incidence, heart rate changes, and an effect of environmental temperature. J. Pediatr. 43 (1969) 510-518
10. Davi M.J., Sankaran K., Simons K.J., Simons E.R., Seshia M.M., and Rigatto H. Physiologic changes induced by theophylline in the treatment of apnea in preterm infants. J. Pediatr. 92 (1978) 91-95
11. Downing S.E., and Lee J.C. Laryngeal chemosensitivity: a possible mechanism of sudden infant death. Pediatrics 55 (1975) 640-649
12. Filiano J.J., and Kinney H.C. A perspective on neuropathological findings in victims of the sudden infant death syndrome: the triple-risk model. Biol. Neonate 65 (1994) 194-197
13. Graves C., Glass L., Laporta D., Meloche R., and Grassino A. Respiratory phase locking during mechanical ventilation in anesthetized subjects. Am. J. Physiol. 250 (1986) R902-R909
14. Grogaard J., Lindstrom D.P., Stahlman M.T., Marchal F., and Sundell H. The cardiovascular response to laryngeal water administration in young lambs. J. Dev. Physiol. 4 (1982) 353-370
15. Haraguchi S., Fung R.Q., and Sasaki R. Effect of hyperthermia on the laryngeal closure reflex. Implications in the sudden infant death syndrome. Ann. Otol. Rhinol. Laryngol. 92 (1983) 24-28
16. Hayakawa T., Takanaga A., Maeda S., Seki M., and Yajima Y. Subnuclear distribution of afferents from the oral, pharyngeal and laryngeal regions in the nucleus tractus solitarii of the rat: a study using transganglionic transport of cholera toxin. Neurosci. Res. 39 (2001) 221-232
17. 2A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats. J. Neurochem. 92 (2005) 1542-1549
18. Hunt C.E. Abnormal hypercarbic and hypoxic sleep arousal responses in near-miss SIDS infants. Pediatr. Res. 15 (1981) 1462-1464
19. Hunt C.E. The cardiorespiratory control hypothesis for sudden infant death syndrome. Clin. Perinatol. 19 (1992) 757-771
20. Hunt C.E., Brouillette R.T., and Hanson D. Theophylline improves pneumogram abnormalities in infants at risk for sudden infant death syndrome. J. Pediatr. 103 (1983) 969-974
21. Inoue S., and Murakami N. Unit responses in the medulla oblongata of rabbit to changes in local and cutaneous temperature. J. Physiol. 259 (1976) 339-356
22. Jiang C., and Lipski J. Synaptic inputs to medullary respiratory neurons from superior laryngeal afferents in the cat. Brain Res. 584 (1992) 197-206
23. 2 partial pressure. J. Appl. Physiol. 53 (1982) 105-109
24. Lee J.C., Stoll B.J., and Downing S.E. Properties of the laryngeal chemoreflex in neonatal piglets. Am. J. Physiol. 233 (1977) R30-R36
25. Leiter J.C., and Böhm I. Mechanisms of pathogenesis in the sudden infant death syndrome (SIDS). Respir. Physiol. Neurobiol. 159 (2007) 127-138
26. Litmanovitz I., Dreshaj I., Miller M.J., Haxhiu M.A., and Martin R.J. Central chemosensitivity affects respiratory muscle responses to laryngeal stimulation in the piglet. J. Appl. Physiol. 76 (1994) 403-408
27. Luna L.G. Histopathologic Methods and Color Atlas of Special Stains and Tissue Artifacts (1992), American Histolabs Inc., Gaithersburg
28. Martin R.J., Wilson C.G., Abu-Shaweesh J.M., and Haxhiu M.A. Role of inhibitory neurotransmitter interactions in the pathogenesis of neonatal apnea: implications for management. Semin. Perinatol. 28 (2004) 273-278
29. 2A receptors mediate GABAergic inhibition of respiration in rats. J. Appl. Physiol. 100 (2006) 91-97
30. Merazzi D., and Mortola J.P. Effects of changes in ambient temperature on the Hering-Breuer reflex of the conscious newborn rat. Pediatr. Res. 45 (1999) 370-376
31. Miller A.J. Characterization of the postnatal development of superior laryngeal nerve fibers in the postnatal kitten. J. Neurobiol. 7 (1976) 483-494
32. Mitra J., Prabhakar N.R., Haxhiu M.A., and Cherniack N.S. The effects of hypercapnia and cooling the ventral medullary surface on capsaicin induced respiratory reflexes. Respir. Physiol. 60 (1985) 377-385
33. Niblock M.M., Luce C.J., Belliveau R.A., Paterson D.S., Kelley M.L., Sleeper L.A., Filiano J., and Kinney H.C. Comparative anatomical assessment of the piglet as a model for the developing human medullary serotonergic system. Brain Res. Rev. 50 (2005) 169-183
34. Ochi M., Koga K., Kurokawa M., Kase H., Nakamura J.-I., and Kuwana Y. Systemic administration of adenosine A2A receptor antagonist reverses increased GABA release in the globus pallidus of unilateral 6-hydroxydopamine-lesioned rats: a microdialysis study. Neuroscience 100 (2000) 53-62
35. Patrickson J.W., Smith T.E., and Zhou S.-S. Afferent projections of the superior and recurrent laryngeal nerves. Brain Res. 539 (1991) 169-174
36. Perlstein P.H., Edwards N.K., and Sutherland J.M. Apnea in premature infants and incubator-air-temperature changes. N. Engl. J. Med. 282 (1970) 461-466
37. Petrillo G.A., Glass L., and Trippenbach T. Phase locking of the respiratory rhythm in cats to a mechanical ventilator. Can. J. Physiol. Pharmacol. 61 (1983) 599-607
38. Phillis J.W. Inhibitory action of CGS 21680 on cerebral cortical neurons is antagonized by bicuculline and picrotoxin-is GABA involved?. Brain Res. 807 (1998) 193-198
39. Rainnie D.G., Grunze H.C., McCarley R.W., and Greene R.W. Adenosine inhibition of mesopontine cholinergic neurons: implications for EEG arousal. Science 263 (1994) 689-692
40. Remmers J.E., Richter D.W., Ballantyne D., Bainton C.R., and Klein J.P. Reflex prolongation of stage I of expiration. Pflugers Arch. 407 (1986) 190-198
41. Schmidt B.J., Roberts R.S., Davis P.B., Doyle L.W., Barrington K.J., Ohisson A., Solimano A., and Tin W. Caffeine therapy for apnea of prematurity. N. Eng. J. Med. 354 (2006) 2112-2121
42. Sun M.-H., Hildebrandt L., Curran A.K., Darnall R.A., Chen G., and Filiano J.J. Potassium permanganate can mark the site of microdialysis in brain sections. J. Histotechnol. 23 (2000) 151-154
43. Thach B.T. Maturation and transformation of reflexes that protect the laryngeal airway from liquid aspiration from fetal to adult life. Am. J. Med. 111 (2001) 69S-77S
44. van der Velde L., Curran A., Filiano J.J., Darnall R.A., Bartlett Jr. D., and Leiter J.C. Prolongation of the laryngeal chemoreflex after inhibition of the rostroventral medulla in piglets: a role in SIDS?. J. Appl. Physiol. 94 (2003) 1883-1895
45. 2A receptors interact with GABAergic pathways to modulate respiration in neonatal piglets. Respir. Physiol. Neurobiol. 141 (2004) 201-211
46. Woodson G.E., and Brauel G. Arterial chemoreceptor influences on the laryngeal chemoreflex. Otolaryngol. Head Neck Surg. 107 (1992) 775-782
47. Xia L., Damon T., Niblock M.M., Bartlett Jr. D., and Leiter J.C. Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets. J. Appl. Physiol. 103 (2007) 1864-1872
48. Xia L., Damon T.A., Leiter J.C., and Bartlett Jr. D. Focal warming of the nucleus of the solitary tract prolongs the laryngeal chemoreflex in decerebrate piglets. J. Appl. Physiol. 102 (2006) 54-62
49. Xia L., Leiter J.C., and Bartlett Jr. D. Laryngeal water receptors are insensitive to body temperature in neonatal piglets. Respir. Physiol. Neurobiol. 150 (2005) 82-86
50. Xia L., Leiter J.C., and Bartlett Jr. D. Laryngeal apnea in rat pups: effects of age and body temperature. J. Appl. Physiol. 104 (2008) 269-274
51. Zaidi S.I.A., Jafri A., Martin R.J., and Haxhui M.A. Adenosine A2A receptors are expressed by GABAergic neurons of medulla oblongata in developing rat. Brain Res. 1071 (2006) 42-53