An adenosine A2A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats

Journal of Neurochemistry

Volumn 92, Issue 6, 2005, Pages 1542-1549

  Hong, Zong Yuan ^a,b   Huang, Zhi Li ^b,c   Qu, Wei Min ^b   Eguchi, Naomi ^b   Urade, Yoshihiro ^b   Hayaishi, Osamu ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c FUDAN UNIVERSITY   (China)

Author keywords

aminobutyric acid; Adenosine A2A receptor agonist; Histamine; Microdiaiysis; Sleep; Tuberomammillary nucleus

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 AMINOBUTYRIC ACID; ADENOSINE A2A RECEPTOR; HISTAMINE; PICROTOXIN; URETHAN; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ADENOSINE; ANTIHYPERTENSIVE AGENT; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; FOREBRAIN; FRONTAL CORTEX; HISTAMINE RELEASE; MALE; MEDIAL PREOPTIC AREA; MICRODIALYSIS; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; RAT; SLEEP INDUCTION; SUBARACHNOID SPACE; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; FRONTAL LOBE; LATERAL HYPOTHALAMUS; METABOLISM; NERVE CELL INHIBITION; NERVE TRACT; PHYSIOLOGY; PREOPTIC AREA; SLEEP; SPRAGUE DAWLEY RAT;

ADENOSINE; ANIMALS; ANTIHYPERTENSIVE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; FRONTAL LOBE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HISTAMINE; HYPOTHALAMIC AREA, LATERAL; MALE; MICRODIALYSIS; NEURAL INHIBITION; NEURAL PATHWAYS; PHENETHYLAMINES; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A2A; RECEPTORS, GABA-A; SLEEP;

EID: 15244362192     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02991.x     Document Type: Article

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