Effects of acute exposure to cadmiun on response to estrogen in the prepuberal rat uterus;Efectos de exposición aguda a cadmio en la acción de estrógenos en útero de rata impúber

Revista Chilena de Pediatria

Volumn 79, Issue 4, 2008, Pages 373-380

  Tchernitchin, Andrei N ^a   Olivares, Francisca ^a,c   Aranda, Carlos ^a   Bustamante, Rodrigo A ^a   Gaete, Leonardo ^a   Ferrada, Karla ^a   Villagra, Rebeca ^a   Vera, Jeanette ^a   Iturbe, Ricardo J ^a,d   Kim, Yoon A ^a,d   Hernández, Natalia B ^a,d   Bizjak, Tina ^b   Novsak, Spela ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF GRAZ   (Austria)

^c Tesis de Titulación de Ingeniero Ambiental ^*

^d UNIVERSITY OF CHILE   (Chile)

Author keywords

Cadmium; Estrogen; Estrogen responses; Immature rat; Toxicity; Uterus

Indexed keywords

CADMIUM; ESTRADIOL; ESTROGEN RECEPTOR;

ANIMAL TISSUE; ARTICLE; DYSMENORRHEA; FEMALE; INFERTILITY; MENSTRUAL CYCLE; MYOMETRIUM; NONHUMAN; PREPUBERTY; PROTEIN INTERACTION; RAT; SPONTANEOUS ABORTION; UTERUS;

EID: 56449094474     PISSN: 03704106     EISSN: 07176228     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Goyer RA, Liu J, Waalkes MP: Cadmium and cancer of prostate and testis. Biometals 2004; 17: 555-8.
2. Sahmoun AE, Case LD, Jackson SA, Schwartz GG: Cadmium and prostate cancer: a critical epidemiologic analysis. Cancer Invest 2005; 23: 256-63.
3. Nishijo M, Morikawa Y, Nakagawa H, et al: Causes of death and renal tubular dysfunction in residents exposed to cadmium in the environment. Occup Environ Med 2006; 63: 545-50.
4. Saskena SK, Salmonsen R: Effects of cadmium chloride on ovulation and on induction of sterility in the female golden hamster. Biol Reprod 1983; 29: 249-56.
5. Copius Peereboom-Stegeman JH, Jongstra-Spaapen E, Leene W, et al: The effects of long-term exposure to cadmium on the small blood vessels in the rat uter-us: a light microscopic study. Ecotoxicol Environ Saf 1987; 14: 288-97.
6. Rehm S, Waalkes MP: Cadmium-induced ovarian toxicity in hamsters, mice, and rats. Fundam Appl Toxicol 1988; 10: 635-47.
7. Levin AA, Plautz JR, di Sant'Agnese PA, Miller RK: Cadmium: pla-cental mechanisms of fetal toxicity. Placenta 1981; Suppl 3: 303-18.
8. Sipowicz M, Kostrzewska A, Laudanski T, Akerlund M: Effects of cad-mium on myometrial activity of the nonpregnant human. Interactions with calcium and oxytocin. Acta Obstet Gynecol Scand 1995; 74: 93-6.
9. Wang X, Tian J: Health risks related to residential exposure to cadmium in Zhenhe County, China. Arch Environ Health 2004; 59: 324-30.
10. Yang K, Julan L, Rubio F, Sharma A, Guan H: Cadmium reduces 11 beta-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells. Am J Physiol Endocrinol Metab 2006; 290: E135-42.
11. Nagata C, Nagao Y, Shibuya C, Kashiki Y, Shimizu H: Urinary cad-mium and serum levels of estrogens and androgens in postmenopausal Japanese women. Cancer Epidemiol Biomarkers Prev 2005; 14: 705-8.
12. Stoica A, Katzenellenbogen BS, Martin MB: Activation of estrogen receptor alpha by the heavy metal cadmium. Mol Endocrinol 2000; 14: 545-53.
13. Safe S: Cadmium's disguise dupes the estrogen receptor. Nature Med 2003; 9: 1000-1.
14. Johnson MD, Kenney N, Stoica A, et al: Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nat Med 2003; 9: 1081-84.
15. Martínez-Campa C, Alonso-González C, Mediavilla MD, et al: Melatonin inhibits both ER alpha activation and breast cancer cell proliferation induced by a metalloestrogen, cadmium. J Pineal Res 2006; 40: 291-6.
16. Young PC, Cleary RE, Ragan WD: Effect of metal ions on the binding of 17beta-estradiol to human endometrial cytosol. Fertil Steril 1977; 28: 459-63.
17. Jensen EV, DeSombre ER: Mechanism of action of the female sex hormones. Annu Rev Biochem 1972; 41: 203-30.
18. Collao C, Tchernitchin A: Effect of sulphydryl group blockage on estrogen binding by the receptors of the uterine eosinophils. IRCS Med Sci 1976; 4: 87.
19. Tchernitchin AN, Mena MA, Rodríguez A, Maturana M: Radioauto-graphic localization of estrogen receptors in the rat uterus: a tool for the study of classical and nontraditional mechanisms of hormone action. En: Pertschuk LP, Lee SH, eds. Localization of Putative Steroid Receptors, Vol. 1, Experimental Systems, Boca Raton, Florida, U.S.A.: Editorial CRC Press, 1985; 5-37.
20. 3H oestradiol-17β incorporation into rat uterus. Steroids 1967; 10: 661-8.
21. Tchernitchin A, Tchernitchin X, Robel P, Baulieu EE: Liaison de l'oestradiol dans les leucocytes polinucléaires éosinophiles humains. C R Acad Sci Paris 1975; 280 (Serie D): 1477-80.
22. Tchernitchin AN, Mena MA, Soto J, Unda C: The role of eosinophils in the action of estrogens and other hormones. Med Sci Res 1989; 17: 5-10.
23. Tchernitchin A, Roorijck J, Tchernitchin X, Vandenhende J, Galand P: Dramatic early increase in uterine eosinophils after oestrogen administration. Nature 1974; 248: 142-3.
24. Tchernitchin AN: Eosinophil-mediated non-genomic parameters of estrogen stimulation: A separate group of responses mediated by an independent mechanism. J Steroid Biochem 1983; 19: 95-100.
25. Galand P, Tchernitchin N, Tchernitchin AN: Dissociation of uterine eosinophilia and water imbibition from other estrogen-induced responses by nafoxidine pretreatment. Mol Cell Endocrinol 1985; 42: 227-33.
26. Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson J-A: Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 1996; 93: 5925-30.
27. Nilsson S, Mäkelä S, Treuter E, et al: Mechanisms of estrogen action. Physiol Rev 2001; 81: 1535-65.
28. Sakamoto H, Matsuda KI, Hosokawa K, et al: Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology 2007; 148: 5842-50.
29. Tchernitchin AN, Tchernitchin N: Imprinting of paths of heterodifferentiation by prenatal or neonatal exposure to hormones, pharmaceuticals, pollutants and other agents and conditions. Med Sci Res 1992; 20: 391-397.
30. Baranski B, Sitarek K: Effect of oral and inhalation expusure to cadmium on the oestrus cycle in rats. Toxicol Lett 1987; 36: 267-73.
31. Grunert G, Fernández S, Tchernitchin AN: Methods for the evaluation of responses to estrogen in individual cell types or regions of the uterus. Hormone Res 1984; 19: 253-62.
32. Grunert G, Porcia M, Tchernitchin AN: Differential potency of oestradiol-17β and diethylstilboestrol on separate groups of responses in the rat uterus. J Endocrinol 1986; 110: 103-14.
33. Tchernitchin NN, Villagra A, Tchernitchin AN: Antiestrogenic activity of lead. Environ Toxicol Water Qual 1998; 13: 43-53.
34. Snedecor GW, Cochran WG: One way classifications. Analysis of variance. En: Snedecor GW, Cochran WG, eds. Statistical Methods. 6a ed., Ames, Iowa, USA: Editorial Iowa State University, 1967; 258-98.
35. Tchernitchin AN, Galand P: Oestrogen levels in the blood, not in the uterus, determine uterine eosinophilia and oedema. J Endocrinol 1983; 99: 123-30.
36. Mena MA, Grunert G, Mansilla MS, et al: Inhibition of non-genomic responses to oestrogen in the rat uterus by testosterone propionate. J Reprod Fertil 1985; 74: 1-7.
37. Bustos S, Soto J, Tchernitchin AN: Estrogenic activity of p,p′-DDT. Environ Toxicol Water Qual 1996; 11: 265-71.
38. Tchernitchin AN, Tchernitchin NN, Mena MA, Unda C, Soto J: Imprinting: Perinatal exposures cause the development of diseases during the adult age. Acta Biol Hung 1999; 50: 425-40.
39. Tchernitchin AN, Mena MA: Efectos diferidos de contaminantes ambientales y otros agentes en salud reproductiva y sexualidad: un desafío pendiente de la toxicología de la reproducción para la salud de las futuras generaciones. Cuad Med Soc (Chile) 2006; 46: 176-94.