Tolerability of β-blocker initiation and titration with bisoprolol and carvedilol in congestive heart failure - A randomized comparison

Cardiology

Volumn 102, Issue 3, 2004, Pages 160-165

  Galatius, Søren ^a,b   Gustafsson, Finn ^a   Atar, Dan ^a   Hildebrandt, Per R ^a  

^a FREDERIKSBERG HOSPITAL   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Blocker; Heart failure; Left ventricular dysfunction; Tolerability

Indexed keywords

BISOPROLOL; BRAIN NATRIURETIC PEPTIDE; CARVEDILOL;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG TOLERABILITY; FEMALE; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; TITRIMETRY;

ADRENERGIC BETA-ANTAGONISTS; AGED; BISOPROLOL; CARBAZOLES; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MAXIMUM TOLERATED DOSE; PROPANOLAMINES; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 5644287397     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000080485     Document Type: Article

References (14)

1. Remme WJ, Swedberg K: Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J 2001;22:1527-1560.
2. Packer M, Fowler MB, Roecker EB, Coats AJ, Katus HA, Krum H, Mohacsi P, Rouleau JL, Tendera M, Staiger C, Holcslaw TL, Amann-Zalan I, DeMets DL: Effect of carvedilol on the morbidity of patients with severe chronic heart failure: Results of the carvedilol prospective randomized cumulative survival (Copernicus) study. Circulation 2002;106:2194-2199.
3. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999;353:2001-2007.
4. The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): A randomised trial. Lancet 1999;353:9-13.
5. Krum H, Roecker EB, Mohacsi P, Rouleau JL, Tendera M, Coats AJ, Katus HA, Fowler MB, Packer M: Effects of initiating carvedilol in patients with severe chronic heart failure: Results from the Copernicus Study. JAMA 2003;289:712-718.
6. Poole-Wilson PA, Swedberg K, Cleland JG, Di Lenarda A, Hanrath P, Komajda M, Lubsen J, Lutiger B, Metra M, Remme WJ, Torp-Pedersen C, Scherhag A, Skene A: Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): Randomised controlled trial. Lancet 2003;362:7-13.
7. Galatius S, Gustafsson F, Nielsen PH, Atar D, Hildebrandt PR: An integrated approach to diagnosis and therapeutic management of patients with systolic heart failure in the Copenhagen metropolitan area. Am Heart J 2002;144:E2.
8. Ansari M, Shlipak MG, Heidenreich PA, Van Ostaeyen D, Pohl EC, Browner WS, Massie BM: Improving guideline adherence: a randomized trial evaluating strategies to increase beta-blocker use in heart failure. Circulation 2003;107:2799-2804.
9. Baxter AJ, Spensley A, Hildreth A, Karimova G, O'Connell JE, Gray CS: Beta blockers in older persons with heart failure: Tolerability and impact on quality of life. Heart 2002;88:611-614.
10. Butler J, Khadim G, Belue R, Chomsky D, Dittus RS, Griffin M, Wilson JR: Tolerability to beta-blocker therapy among heart failure patients in clinical practice. J Card Fail 2003;9:203-209.
11. Cowie MR, Wood DA, Coats AJ, Thompson SG, Suresh V, Poole-Wilson PA, Sutton GC: Survival of patients with a new diagnosis of heart failure: A population based study. Heart 2000;83:505-510.
12. Fox KF, Cowie MR, Wood DA, Coats AJ, Poole-Wilson PA, Sutton GC: A Rapid Access Heart Failure Clinic provides a prompt diagnosis and appropriate management of new heart failure presenting in the community. Eur J Heart Fail 2000;2:423-429.
13. Gottlieb SS, Fisher ML, Kjekshus J, Deedwania P, Gullestad L, Vitovec J, Wikstrand J: Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). Circulation 2002;105:1182-1188.
14. Krum H, Ninio D, MacDonald P: Baseline predictors of tolerability to carvedilol in patients with chronic heart failure. Heart 2000;84:615-619.