Intrinsic noise, gene regulation and steady-state statistics in a two-gene network

Journal of Theoretical Biology

Volumn 231, Issue 4, 2004, Pages 563-568

  Tao, Yi ^a  

^a WILFRID LAURIER UNIVERSITY   (Canada)

Author keywords

Gene expression; Gene network; Intrinsic noise

Indexed keywords

REPRESSOR PROTEIN;

GENE EXPRESSION; MODEL;

ARTICLE; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENE SWITCHING; MATHEMATICAL MODEL; NOISE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STEADY STATE;

ANIMALS; GENE EXPRESSION REGULATION; GENES, SWITCH; MODELS, GENETIC; MODELS, STATISTICAL; REPRESSOR PROTEINS;

EID: 5644239681     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtbi.2004.07.012     Document Type: Article

References (18)

1. A. Arkin, J. Ross, and H.H. McAdams Stochastic kinetic analysis of developmental pathway bifurcation in phage λ -infected Escherichia coli cells Genetics 149 1998 1633 1648
2. O.G. Berg, J. Paulsson, and M. Ehrenberg Fluctuations in repressor control thermodynamic constraints on stochastic focusing Biophys. J. 79 2000 2944 2953
3. J.L. Cherry, and F. Adler How to make a biological switch J. Theor. Biol. 203 2000 117 133
4. O. Cinquin, and J. Demongeot Positive and negative feedback striking a balance between necessary and antagonists J. Theor. Biol. 216 2002 229 241
5. T.S. Gardner, C.R. Cantor, and J.J. Collins Construction of a genetic toggle switch in Escherichia coli Nature 403 2000 339 342
6. J. Hasty, and J.J. Collings Translating the noise Nat. Genet. 31 2002 13 14
7. J. Hasty, J. Pradlines, M. Donlink, and J.J. Collins Noise-based switch and amplifiers for gene expression Proc. Natl Acad. Sci. 97 2000 2075 2080
8. F. Isaacs, J. Hasty, C.R. Cantor, and J.J. Collins Prediction and measurement of an autoregulatory genetic module Proc. Natl Acad. Sci. 100 2003 7714 7719
9. A.D. Keller Model genetic circuits encoding autoregulatory transcription factors J. Theor. Biol. 172 1995 169 185
10. T.B. Kepler, and T.C. Elston Stochasticity in transcriptional regulation origins, consequences, and mathematical representations Biophys. J. 81 2001 3116 3136
11. H.H. MacAdams, and A. Arkin Stochastic mechanism in gene expression Proc. Natl Acad. Sci. 94 1997 814 819
12. E.M. Ozbudak, M. Thattai, I. Kurtser, A.D. Grossman, and A. van Oudenaarden Regulation of noise in the expression of a single gene Nat. Genet. 31 2002 69 73
13. J. Paulsson, and M. Ehrenberg Random signal fluctuations can reduce random fluctuations in regulated components of chemical regulatory networks Phys. Rev. Lett. 84 2000 5447 5450
14. J. Paulsson, O.G. Berg, and M. Ehrenberg Stochastic focusing fluctuation-enhanced sensitivity of intracellular regulation Proc. Natl Acad. Sci. 97 2000 7148 7153
15. M. Sasai, and P.G. Wolynes Stochastic gene expression as many-body problem Proc. Natl Acad. Sci. 100 2003 2374 2379
16. Y. Tao Intrinsic and external noise in an auto-regulatory genetic network J. Theor. Biol. 229 2004 147 156
17. M. Thattai, and A. van Oudenaarden Intrinsic noise in gene regulatory networks Proc. Natl Acad. Sci. 98 2001 8614 8619
18. N.G. Van Kampen Stochastic Process Theory in Physics and Chemistry 1992 North-Holland Amsterdam