Serine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibition

Journal of Biological Chemistry

Volumn 279, Issue 41, 2004, Pages 42687-42693

  Bennett, Richard L ^a   Blalock, William L ^a   May, W Stratford ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b Box 100232 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; LIVING SYSTEMS STUDIES; RNA;

APOPTOSIS; CELLULAR ACTIVATORS; TRANSLATION INHIBITION;

AMINO ACIDS;

DOUBLE STRANDED RNA; INITIATION FACTOR 2; PROTEIN KINASE; PROTEIN KINASE R; PROTEIN RAX; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN COS7; CELL VIABILITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; SIGNAL TRANSDUCTION; STRESS;

AMINO ACID SEQUENCE; ANIMALS; ANNEXIN A5; APOPTOSIS; BINDING SITES; BLOTTING, WESTERN; CELL DEATH; CELL SURVIVAL; EIF-2 KINASE; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; EYE PROTEINS; FLOW CYTOMETRY; GENES, DOMINANT; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOPRECIPITATION; INTERLEUKIN-3; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, DOUBLE-STRANDED; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS;

ANIMALIA; EUKARYOTA; MURINAE;

EID: 5644234968     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403321200     Document Type: Article

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