Inhibitors designed for presenilin 1 by means of aspartic acid activation: Preliminary communication

Helvetica Chimica Acta

Volumn 87, Issue 9, 2004, Pages 2334-2340

  Larbig, Gregor ^a   Zall, Andrea ^a   Schmidt, Boris ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOASSAY; CRYSTALLIZATION; DRUG PRODUCTS; ESTERS; NUCLEAR MAGNETIC RESONANCE;

DRUG DEVELOPMENT; INHIBITORS;

ORGANIC ACIDS;

(CYCLOPROPYLMETHYL)ESTER; 1 CYCLOPROPYLETHYL [[N [(3,5 DIFLUOROPHENYL)ACETYL]ALANYL]AMINO](PHENYL)ACETATE; ASPARTIC ACID; ASPARTIC PROTEINASE; AZO COMPOUND; CYCLOPROPYLMETHYL [[N [(3,5 DIFLUOROPHENYL)ACETYL]ALANYL]AMINO](PHENYL)ACETATE; DICYCLOPROPYLMETHYL [[N [(3,5 DIFLUOROPHENYL)ACETYL]ALANYL]AMINO](PHENYL)ACETATE; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; L 685458; LY 374973; LY 411575; PRESENILIN 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AQUEOUS SOLUTION; ARTICLE; BIOASSAY; CONTROLLED STUDY; CRYSTALLIZATION; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE; PH; PRIORITY JOURNAL;

EID: 5644227461     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200490208     Document Type: Article

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