Effect of meloxicam and carprofen on renal function when administered to healthy dogs prior to anesthesia and painful stimulation

American Journal of Veterinary Research

Volumn 65, Issue 10, 2004, Pages 1384-1390

  Crandell, Dawn E ^a   Mathews, Karol A ^a   Dyson, Doris H ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACEPROMAZINE MALEATE; BUTORPHANOL TARTRATE; CARPROFEN; CREATININE; DIAZEPAM; ISOFLURANE; KETALEAN; KETAMINE; MELOXICAM; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGEN; PENTETATE TECHNETIUM TC 99M; SODIUM CHLORIDE; UREA;

ANESTHESIA; ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ARTICLE; BREATHING RATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOG; ELECTROSTIMULATION; EXPERIMENTAL DESIGN; FEMALE; GLOMERULUS FILTRATION RATE; HEART RATE; KIDNEY FUNCTION; MALE; MEAN ARTERIAL PRESSURE; MINIMUM LUNG ALVEOLUS CONCENTRATION; MONITORING; NONHUMAN; PAIN; PLASMA CLEARANCE; PREMEDICATION; RANDOMIZATION; STANDARDIZATION; STATISTICAL SIGNIFICANCE; UREA BLOOD LEVEL;

ANESTHESIA; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; BLOOD PRESSURE; CARBAZOLES; CREATINE; CROSS-OVER STUDIES; DOGS; ELECTRIC STIMULATION; FEMALE; GLOMERULAR FILTRATION RATE; HEART RATE; KIDNEY; MALE; RESPIRATION; THIAZINES; THIAZOLES; UREA;

ANIMALIA; CANIS FAMILIARIS; GLOMERULUS;

EID: 5644224756     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2004.65.1384     Document Type: Article

References (60)

1. Mathews KA, Pettifer G, Foster R, et al. Safety and efficacy of preoperative administration of meloxicam, compared with that of ketoprofen and butorphanol in dogs undergoing abdominal surgery. Am J Vet Res 2001;62:882-888.
2. Grisneaux E, Pibarot P, Dupuis J, et al. Comparison of ketoprofen and carprofen administered prior to orthopedic surgery for control of postoperative pain in dogs. J Am Vet Med Assoc 1999; 215:1105-1110.
3. Gogny M. Pharmacological profile and therapeutic value of meloxicam, in Proceedings. Recent Adv Nonsteroidal Anti-Inflammatory Ther Small Anim 1999;35-40.
4. Lascelles BD, Cripps PJ, Jones A, et al. Efficacy and kinetics of carprofen, administered preoperatively or postoperatively, for the prevention of pain in dogs undergoing ovariohysterectomy. Vet Surg 1998;27:568-582.
5. Nolan A, Reid J. Comparison of the postoperative analgesic and sedative effects of carprofen and papaveretum in the dog. Vet Rec 1993;133:240-242.
6. Ferreira SH. Peripheral analgesic sites of action of anti-inflammatory drugs. Int J Clin Pract Suppl 2002;2-10.
7. McCrory CR, Lindahl SG. Cyclooxygenase inhibition for postoperative analgesia. Anesth Analg 2002;95:169-176.
8. Vanegas H, Schaible HG. Prostaglandins and cyclooxygenases in the spinal cord. Prog Neurobiol 2001;64:327-363.
9. Woolf CJ, Chong MS. Preemptive analgesia - treating postoperative pain by preventing the establishment of central sensitization. Anesth Analg 1993;77:362-379.
10. Dunn MJ, Zambraski EJ. Renal effects of drugs that inhibit prostaglandin synthesis. Kidney Int 1980;18:609-622.
11. Lonigro AJ, Itskovitz HD, Crowshaw K, et al. Dependency of renal blood flow on prostaglandin synthesis in the dog. Circ Res 1973;32:712-717.
12. Venuto RC, O'Dorisio T, Ferris TF, et al. Prostaglandins and renal function. II. The effect of prostaglandin inhibition on autoregulation of blood flow in the intact kidney of the dog. Prostaglandins 1975;9:817-828.
13. Echtenkamp SF, Davis JO, DeForrest JM, et al. Effects of indomethacin, renal denervation, and propranolol on plasma renin activity in conscious dogs with chronic thoracic caval constriction. Circ Res 1981;49:492-500.
14. Oliver JA, Sciacca RR, Pinto J, et al. Participation of the prostaglandins in the control of renal blood flow during acute reduction of cardiac output in the dog. J Clin Invest 1981;67:229-237.
15. Oliver JA, Sciacca RR, Cannon PJ. Renal vasodilation by converting enzyme inhibition. Role of renal prostaglandins. Hypertension 1983;5:166-171.
16. Schnermann J, Briggs JP. Participation of renal cortical prostaglandins in the regulation of glomerular filtration rate. Kidney Int 1981;19:802-815.
17. Zambraski EJ. The effects of nonsteroidal anti-inflammatory drugs on renal function: experimental studies in animals. Semin Nephrol 1995;15:205-213.
18. Harris RC. Cyclooxygenase-2 in the kidney. J Am Soc Nephrol 2000;11:2387-2394.
19. Schnitzer TJ. Cyclooxygenase-2-specific inhibitors: are they safe? Am J Med 2001;110:465-495.
20. Eras J, Perazella MA. NSAIDs and the kidney revisited: are selective cyclooxygenase-2 inhibitors safe? Am J Med Sci 2001;321:181-190.
21. Breyer MD, Hao CM, Qi Z. Cyclooxygenase-2 selective inhibitors and the kidney. Curr Opin Crit Care 2001;7:393-400.
22. Engelhardt G, Bogel R, Schnitzer C, et al. Meloxicam: influence on arachidonic acid metabolism. Part 1. In vitro findings. Biochem Pharmacol 1996;51:21-28.
23. Kay-Mugford P, Benn SJ, LaMarre J, et al. In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs. Am J Vet Res 2000;61:802-810.
24. Canadian Council on Animal Care. Guide to the care and use of experimental animals. 1st ed. Ottawa: Canadian Council on Animal Care, 1984.
25. Jones B, Kenward MG. Design and analysis for three or more treatments. In: Jones B, Kenward MG, eds. Design and analysis of cross-over trials. 1st ed. London: Chapman & Hall, 1989; 189-241.
26. Steffey EP, Howland D Jr. Isoflurane potency in the dog and cat. Am J Vet Res 1977;38:1833-1836.
27. Valverde A, Dyson DH, McDonell WN. Epidural morphine reduces halothane MAC in the dog. Can J Anaesth 1989;36:629-632.
28. Powers TE, Powers JD, Garg RC. Study of the double isotope single-injection method for estimating renal function in pure-bred Beagle dogs. Am J Vet Res 1977;38:1933-1936.
29. Ko JC, Miyabiyashi T, Mandsager RE, et al. Renal effects of carprofen administered to healthy dogs anesthetized with propofol and isoflurane. J Am Vet Med Assoc 2000;217:346-349.
30. Lobetti RG, Joubert KE. Effect of administration of non-steroidal anti-inflammatory drugs before surgery on renal function in clinically normal dogs. Am J Vet Res 2000;61:1501-1507.
31. Balachandran S, Toguri AG, Petrusick TW, et al. Comparative evaluation of quantitative glomerular filtration rate measured by isotopic and nonisotopic methods. Clin Nucl Med 1981;6:150-153.
32. Forsyth SF, Guilford WG, Pfeiffer DU. Effect of NSAID administration on creatinine clearance in healthy dogs undergoing anaesthesia and surgery. J Small Anim Pract 2000;41:547-550.
33. Rose BD, Post TW. Effects of hormones on renal function. In: Rose BD, Post TW, eds. Clinical physiology of acid-base disorders. 5th ed. New York: McGraw-Hill Book Co, 2001;163-238.
34. Rose BD, Rennke HG. Review of renal physiology. In: Rose BD, Rennke HG, eds. Renal pathophysiology - the essentials. 1st ed. Baltimore, Md: The Williams & Wilkins Co, 1994;20.
35. Priano LL, Bernards C, Marrone B. Effect of anesthetic induction agents on cardiovascular neuroregulation in dogs. Anesth Analg 1989;68:344-349.
36. Ludders JW, Reitan JA, Martucci R, et al. Blood pressure response to phenylephrine infusion in halothane-anesthetized dogs given acetylpromazine maleate. Am J Vet Res 1983;44:996-999.
37. Herbaczynska-Cedro K, Vane JR. Contribution of intrarenal generation of prostaglandin to autoregulation of renal blood flow in the dog. Circ Res 1973;33:428-436.
38. Bostrom I, Nyman G, Kampa N, et al. Effects of acepromazine on renal function in anesthetized dogs. Am J Vet Res 2003;64:590-598.
39. Duke T, Cox AM, Remedios AM, et al. The analgesic effects of administering fentanyl or medetomidine in the lumbosacral epidural space of cats. Vet Surg 1994;23:143-148.
40. Vainio O, Vaha-Vahe T, Palmu L. Sedative and analgesic effects of medetomidine in dogs. J Vet Pharmacol Ther 1989;12:225-231.
41. Nickel B. The antinociceptive activity of flupirtine: a structurally new analgesic. Postgrad Med J 1987;63(suppl 3):19-28.
42. Traynor TR, Smart A, Briggs JP, et al. Inhibition of macula densa-stimulated renin secretion by pharmacological blockade of cyclooxygenase-2. Am J Physiol 1999;277:F706-F710.
43. Henrich WL, Schrier RW, Berl T. Mechanisms of renin secretion during hemorrhage in the dog. J Clin Invest 1979;64:1-7.
44. Schnermann J. Cyclooxygenase-2 and macula densa control of renin secretion. Nephrol Dial Transplant 2001;16:1735-1738.
45. Bonventre JV, Weinberg JM. Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol 2003;14:2199-2210.
46. Moe L, Heiene R. Estimation of glomerular filtration rate in dogs with 99M-Tc-DTPA and iohexol. Res Vet Sci 1995;58:138-143.
47. Heiene R, Moe L. Pharmacokinetic aspects of measurement of glomerular filtration rate in the dog: a review. J Vet Intern Med 1998; 12:401-414.
48. Gleadhill A, Peters AM, Michell AR. A simple method for measuring glomerular filtration rate in dogs. Res Vet Sci 1995;59:118-123.
49. Bovee KC, Joyce T. Clinical evaluation of glomerular function: 24-hour creatinine clearance in dogs. J Am Vet Med Assoc 1979;174:488-491.
50. Barthez PY, Hornof WJ, Cowgill LD, et al. Comparison between the scintigraphic uptake and plasma clearance of 99mTc-diethylenetriaminepentacetic acid (DTPA) for the evaluation of the glomerular filtration rate in dogs. Vet Radiol Ultrasound 1998;39:470-474.
51. Barbour GL, Crumb CK, Boyd CM, et al. Comparison of inulin, iothalamate, and 99mTc-DTPA for measurement of glomerular filtration rate. J Nucl Med 1976;17:317-320.
52. Klopper JF, Hauser W, Atkins HL, et al. Evaluation of 99m Tc-DTPA for the measurement of glomerular filtration rate. J Nucl Med 1972;13:107-110.
53. McAfee JG, Grossman ZD, Gagne G, et al. Comparison of renal extraction efficiencies for radioactive agents in the normal dog. J Nucl Med 1981;22:333-338.
54. Powers TA, Stone WJ, Grove RB, et al. Radionuclide measurement of differential glomerular filtration rate. Invest Radiol 1981;16:59-64.
55. Powers TA, Stone WJ, Lowe BA, et al. Radionuclide measurement of differential glomerular filtration rate in urinary tract obstruction. Invest Radiol 1982;17:417-421.
56. Rehling M, Moller ML, Thamdrup B, et al. Simultaneous measurement of renal clearance and plasma clearance of 99mTc-labelled diethylenetriaminepenta-acetate, 51Cr-labelled ethylenediaminetetra-acetate and inulin in man. Clin Sci (Lond) 1984;66:613-619.
57. Liu KD. Molecular mechanisms of recovery from acute renal failure. Crit Care Med 2003;31:S572-S581.
58. Basile DP, Donohoe D, Roethe K, et al. Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol 2001; 281:F887-F899.
59. McKellar QA, Delatour P, Lees P. Stereospecific pharmacodynamics and pharmacokinetics of carprofen in the dog. J Vet Pharmacol Ther 1994;17:447-454.
60. Poulsen Nautrup B, Horstermann D. Pharmacodynamic and pharmacokinetic aspects of the non-inflammatory non-steroidal agent meloxicam in dogs. Dtsch Tierarztl Wochenschr 1999;106:94-100.