In vitro evidence for a new therapeutic approach in renal cell carcinoma

International Braz J Urol

Volumn 34, Issue 4, 2008, Pages 492-502

  Pittoggi, Carmine ^a   Martis, Gianni ^b   Mastrangeli, Giorgia ^a   Mastrangeli, Bruno ^b   Spadafora, Corrado ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAN CAMILLO DE LELLIS HOSPITAL   (Italy)

Author keywords

Gene expression; Renal cell carcinoma; Reverse transcriptase; Therapy

Indexed keywords

EID: 56349167112     PISSN: 16775538     EISSN: 16776119     Source Type: Journal    
DOI: 10.1590/S1677-55382008000400012     Document Type: Article

References (20)

1. Thoenes W, Störkel S, Rumpelt HJ, Jacobi GH: Renal cell carcinoma- a classification based on cytomorphological criteria. Zentralbl Allg Pathol. 1986; 132: 503-13.
2. Motzer RJ, Hutson TE, Tomczak P, Michaelson MD, Biikowski RM, Rixe O, et al.: Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med. 2007; 356: 115-24.
3. Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Siebels M, et al.: Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med. 2007; 356: 125-34. Erratum. in: N Engl J Med. 2007; 357: 203.
4. Hudes G, Carducci M, Tomczak P, Dutcher J, Figlin R, Kapoor A, et al.: Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med. 2007; 356: 2271-81.
5. Costa LJ, Drabkin HA: Renal cell carcinoma: new developments in molecular biology and potential for targeted therapies. Oncologist. 2007; 12: 1404-15.
6. Mangiacasale R, Pittoggi C, Sciamanna I, Careddu A, Mattei E, Lorenzini R, et al.: Exposure of normal and transformed cells to nevirapine, a reverse transcriptase inhibitor, reduces cell growth and promotes differentiation. Oncogene. 2003; 22: 2750-61.
7. Pyra H, Böni J, Schüpbach J: Ultrasensitive retrovirus detection by a reverse transcriptase assay based on product enhancement. Proc Natl Acad Sci U S A. 1994; 91: 1544-8.
8. Diegmann J, Junker K, Gerstmayer B, Bosio A, Hindermann W, Rosenhahn J, et al.: Identification of CD70 as a diagnostic biomarker for clear cell renal cell carcinoma by gene expression profiling, real-time RT-PCR - and immunohistochemistry. Eur J Cancer. 2005; 41: 1794-801.
9. Shirsat NV, Shaikh, SA:. Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma-cells. Exp Cell Res. 2003; 291: 91-100.
10. Giannelli G, Marinosci F, Trerotoli P, Volpe A, Quaranta M, Dentico P, et al.: SCCA antigen combined with alpha-fetoprotein as serologic markers of HPC. Int J Cancer. 2005; 117: 506-9.
11. Imura A, Hori T, Imada K, kawamata S, Tanaka Y, Imamura S, et al.: OX40 expressed on fresh leukemic cells from adult T-cell leukemia patients mediates cell adhesion to vascular endothelial cells: implication for the possible involvement of OX40 in leukemic cell infiltration. Blood. 1997; 89: 2951-8.
12. Anastasiadis AG, Calvo-Sanchez D, Franke KH, Ebert T, Heydthausen M, Schulz WA, et al.: p27KIP1-expression in human renal cell cancers: implications for clinical outcome. Anticancer Res. 2003; 23: 217-21.
13. Sciamanna I, Landriscina M, Pittoggi C, Quirino M, Mearelli C, Beraldi R, et al.: Inhibition of endogenous reverse transcriptase antagonizes human tumor growth. Oncogene. 2005; 24: 3923-31.
14. Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Lebedeva IV, Dent P, et al.: MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine. Cytokine Growth Factor Rev. 2003; 14: 35-51.
15. Brouha B, Schustak. J, Badge RM, Lutz-Prigge S, Farley A-H, Moran JV, et al.: Hot L1s account for the bulk of retrotransposition in the human population. Proc Natl Acad Sci U S A. 2003; 100: 5280-5.
16. Damm K, Hemmann U, Garin-Chesa P, Hanel N, Kauffmann I, Priepke H, et al.: A highly selective telomerase inhibitor limiting human cancer cell proliferation. EMBO J. 2001; 20: 6958-68.
17. Wischhusen J, Jung G, Radovanovic 1, Beier C, Steinbach JP, Rinmer A, et al.: Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastorna. Cancer Res. 2002; 62: 2592-9.
18. Douin-Echinard V, Bornes S, Roehaix P, Tilkin AF, Peron JM, Bonnet J, a al.: The expression of CD70 nd CD80 by gene-modified tumor cells induces an antitumor response depending on the M-HC status. Cancer Gene Ther. 2000; 7: 1543-56.
19. Tilghman SM: The structure and regulation of the alpha-fetoprotein and albumin genes. Oxf Surv Eukaryot Genes. 1985; 2: 160-206,
20. Yao F, Guo JM, Xu CF, Lou YL, Xiao BX, Zhou WH, et al.: Detecting AFP mRNA in peripheral blood of the patients with hepatocellular carcinoma, liver cirrhosis and hepatitis. Clin Chim. Acta, 2005; 361: 119-27.