Arecoline and the 30-100 kDa fraction of areca nut extract differentially regulate mTOR and respectively induce apoptosis and autophagy: A pilot study

Journal of Biomedical Science

Volumn 15, Issue 6, 2008, Pages 823-831

  Liu, Shyun Yeu ^a,b,c   Lin, Mei Huei ^a,d   Hsu, Yu Rung ^d   Shih, Ya Yun ^d   Chiang, Wei Fan ^a   Lee, Chin Hai ^a   Chou, Ta Hsiung ^a   Liu, Young Chau ^a,e  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^e SHU TE UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Areca nut; Arecoline; Autophagy; Mammalian target of rapamycin (mTOR)

Indexed keywords

ARECA CATECHU EXTRACT; ARECOLINE; BETEL EXTRACT; CASPASE 3; MAMMALIAN TARGET OF RAPAMYCIN; MATRIX METALLOPROTEINASE; PLANT EXTRACT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; BETEL NUT; CARCINOMA CELL; CELL ACTIVITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PIPER BETLE; PRIORITY JOURNAL; WESTERN BLOTTING;

APOPTOSIS; ARECA; AUTOPHAGY; CASPASE 3; CELL LINE, TUMOR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NUTS; PHOSPHORYLATION; PILOT PROJECTS; PLANT EXTRACTS; PROTEIN KINASES; TUMOR CELLS, CULTURED;

ARECA CATECHU; MAMMALIA; PIPER BETEL; PIPER BETLE;

EID: 56349148226     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-008-9273-8     Document Type: Article

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