Synthesis of 2-oxoamides based on sulfonamide analogs of γ-amino acids and their activty on phospholipase A2

Journal of Peptide Science

Volumn 14, Issue 10, 2008, Pages 1111-1120

  Antonopoulou, Georgia ^a,b   Magrioti, Victoria ^a   Stephens, Daren ^c   Constantinou Kokotou, Violetta ^b   Dennis, Edward A ^c   Kokotos, George ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b AGRICULTURAL UNIVERSITY OF ATHENS   (Greece)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2 oxoamides; Acyl sulfonamides; Inhibitors; Phospholipase A2; Sulfonamides

Indexed keywords

2 HYDROXY N [1 (4 METHYLPHENYLSULFONAMIDO)OCTAN 4 YL]HEXADECANAMIDE; 2 HYDROXY N [1 (METHYLPHENYLSULFONAMIDO)OCTAN 4 YL]HEXADECANAMIDE; 2 HYDROXY N [3 (4 METHYLPHENYLSULFONAMIDO)PROPYL]HEXADECANAMIDE; 2 HYDROXY N [3 (METHYLSULFONAMIDO)PROPYL]HEXADECANAMIDE; 2 HYDROXY N [4 (4 METHYLPHENYLSULFONAMIDO) 4 OXOBUTYL]HEXADECANAMIDE; 2 HYDROXY N [4 (4 METHYLPHENYLSULFONAMIDO)BUTYL]HEXADECANAMIDE; 2 HYDROXY N [4 (METHYLSULFONAMIDO) 4 OXOBUTYL]HEXADECANAMIDE; 2 HYDROXY N [4 (METHYLSULFONAMIDO)BUTYL]HEXADECANAMIDE; 2 OXOAMIDE DERIVATIVE; 4 AMINOBUTYRIC ACID; AX 006; AX 007; AX 048; AX 109; ENZYME INHIBITOR; GROUP 4 SECRETED PHOSPHOLIPASE A2; GROUP 6A CALCIUM INDEPENDENT PHOSPHOLIPASE A2; N (3 AMINOPROPYL) 4 METHYLBENZENESULFONAMIDE; N (4 AMINOBUTYL) 4 METHYLBENZENESULFONAMIDE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; TERT BUTYL 1 (4 METHYLPHENYLSULFONAMIDO)OCTAN 4 YLCARBAMATE; TERT BUTYL 1 (METHYLSULFONAMIDO)OCTAN 4 YLCARBAMATE; TERT BUTYL 1 CYANOHEPT 1 EN 3 YLCARBAMATE; TERT BUTYL 1 CYANOHEPTAN 3 YLCARBAMATE; TERT BUTYL 4 (4 METHYLPHENYLSULFONAMIDO) 4 OXOBUTYLCARBAMATE; TERT BUTYL 4 (METHYLSULFONAMIDO) 4 OXOBUTYLCARBAMATE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; HUMANS; ISOENZYMES; PHOSPHOLIPASES A2; PYRIDINES; SULFONAMIDES;

EID: 56349120409     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1048     Document Type: Article

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