Better Regenerative Output After Cellular Input. Healing Hearts by Combining Basic Fibroblast Factor and Cell-Based Therapy

Journal of the American College of Cardiology

Volumn 52, Issue 23, 2008, Pages 1866-1868

  Dimmeler, Stefanie ^a   Tjwa, Marc ^a,b  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

cell therapy; growth factors; regeneration; stem cells

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR;

ACUTE HEART INFARCTION; ANGIOGENESIS; CELL REGENERATION; CELL THERAPY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; EDITORIAL; ENGRAFTMENT; HEART EJECTION FRACTION; HEART FAILURE; HEART MUSCLE PERFUSION; HEART PROTECTION; ISCHEMIC HEART DISEASE; PRIORITY JOURNAL; REVASCULARIZATION; SURVIVAL; SWINE;

ANIMALS; CELL TRANSPLANTATION; DISEASE MODELS, ANIMAL; FIBROBLAST GROWTH FACTOR 2; HEART; HEART FAILURE; HUMANS; MYOCARDIAL ISCHEMIA; NEOVASCULARIZATION, PATHOLOGIC; SWINE; TISSUE THERAPY;

EID: 56349110595     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.07.065     Document Type: Editorial

References (9)

1. Dimmeler S., Burchfield J., and Zeiher A.M. Cell-based therapy of myocardial infarction. Arterioscler Thromb Vasc Biol 28 (2008) 208-216
2. Boodhwani M., Sodha N.R., Laham R.J., and Sellke F.W. The future of therapeutic myocardial angiogenesis. Shock 26 (2006) 332-341
3. Takehara N., Tsutsumi Y., Tateishi K., et al. Controlled delivery of basic fibroblast growth factor promotes human cardiosphere-derived cell engraftment to enhance cardiac repair for chronic myocardial infarction. J Am Coll Cardiol 52 (2008) 1858-1865
4. Smith R.R., Barile L., Cho H.C., et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 115 (2007) 896-908
5. Dimmeler S., and Leri A. Aging and disease as modifiers of efficacy of cell therapy. Circ Res 102 (2008) 1319-1330
6. Davis M.E., Hsieh P.C., Takahashi T., et al. Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A 103 (2006) 8155-8160
7. Mangi A.A., Noiseux N., Kong D., et al. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 9 (2003) 1195-1201
8. Koyanagi M., Bushoven P., Iwasaki M., Urbich C., Zeiher A.M., and Dimmeler S. Notch signaling contributes to the expression of cardiac markers in human circulating progenitor cells. Circ Res 101 (2007) 1139-1145
9. Rosenblatt-Velin N., Lepore M.G., Cartoni C., Beermann F., and Pedrazzini T. FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J Clin Invest 115 (2005) 1724-1733