Response to Milland et al.: Carbohydrate residues downstream of the terminal Galα(1,3)Gal epitope modulate the specificity of xenoreactive antibodies

Immunology and Cell Biology

Volumn 86, Issue 8, 2008, Pages 631-632

  Zhou, Dapeng ^a   Levery, Steven B ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSIDASE; ANTIGEN; CARBOHYDRATE; EPITOPE; GALACTOSYL ALPHA(1,3)GALACTOSE; UNCLASSIFIED DRUG;

ANTIBODY SPECIFICITY; CELL SURFACE; HUMAN; LETTER; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CARBOHYDRATES; CHO CELLS; CRICETINAE; CRICETULUS; DISACCHARIDES; EPITOPES; GALACTOSYLTRANSFERASES; GLYCOSPHINGOLIPIDS; HUMANS; RATS; TRANSFECTION;

EID: 56249143762     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2008.65     Document Type: Letter

References (8)

1. Milland J, Yuriev E, Xing PX, McKenzie IF, Ramsland PA, Sandrin MS. Carbohydrate residues downstream of the terminal Galα(1,3)Gal epitope modulate the specificity of xenoreactive antibodies. Immunol Cell Biol 2007; 85: 623-632. e-pub ahead of print 28 August 2007.
2. Taylor SG, McKenzie IF, Sandrin MS. Characterization of the rat α(1,3)galactosyltransferase: evidence for two independent genes encoding glycosyltransferases that synthesize Galα(1,3)Gal by two separate glycosylation pathways. Glycobiology 2003; 13: 327-337. e-pub ahead of print 17 December 2002.
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8. Christiansen D, Milland J, Mouhtouris E, Vaughan H, Pellicci DG, McConville MJ et al. Humans lack iGb3 due to the absence of functional iGb3-synthase: implications for NKT Cell development and transplantation. PLoS Biol 2008; 6: e172.