Assessment and significance of arterial stiffness in patients with chronic kidney disease

Current Opinion in Nephrology and Hypertension

Volumn 17, Issue 6, 2008, Pages 635-641

  Guérin, Alain R ^a,b,c   Pannier, Bruno ^a,b,c   Métivier, Fabien ^a   Marchais, Sylvain J ^a   London, Gérard M ^a,b,c,d  

^a Hospital Manhes   (France)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d Hopital FH Manhes   (France)

Author keywords

Arterial calcifications; Arterial stiffness; Bone activity; Cardiovascular mortality; Chronic kidney disease; End stage renal disease; Pulse wave velocity

Indexed keywords

AORTA; ARTERIAL STIFFNESS; ARTERY CALCIFICATION; ARTERY COMPLIANCE; BONE METABOLISM; CARDIOVASCULAR RISK; CHRONIC KIDNEY DISEASE; CORRELATION ANALYSIS; ENDOTHELIAL DYSFUNCTION; HUMAN; INFLAMMATION; KIDNEY FUNCTION; MALNUTRITION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULSE WAVE; REVIEW; VITAMIN DEFICIENCY;

AGE FACTORS; ARTERIES; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; COMPLIANCE; HUMANS; KIDNEY DISEASES; KIDNEY FAILURE, CHRONIC; PULSATILE FLOW; RISK FACTORS;

EID: 56249125318     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNH.0b013e32830dcd5c     Document Type: Review

References (94)

1. Blacher J, Guérin AP, Pannier B, et al. Impact of aortic stiffness on survival in end-stage renal disease. Circulation 1999; 99:2434-2439.
2. Shoji T, Emoto M, Shinohara K, et al. Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. J Am Soc Nephrol 2001; 12:2117-2124.
3. Laurent S, Boutouyrie P, Asmar R, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 2001; 37:1236-1241.
4. Boutouyrie P, Tropeano AI, Asmar R, et al. Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study. Hypertension 2002; 39:10-15.
5. Laurent S, Katsahian S, Fassot C, et ai. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke 2003; 34:1203-1206.
6. Cruickshank K, Riste L, Anderson SG, et al. Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance: an integrated index of vascular function. Circulation 2002; 106:2085-2090.
7. Covic A, Haydar AA, Bhamra-Ariza P, et al. Aortic pulse wave velocity and arterial wave reflections predict the extent and severity of coronary artery disease in chronic kidney disease patients. J Nephrol 2005; 18:388-396.
8. Laurent S, Cockcroft J, Van Bortel L, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2008; 27:2588-2605.
9. Pannier B, Guérin AP, Marchais SJ, et al. Arterial structure and function in end-stage renal disease. Artery Res 2007; 1:79-88.
10. Nichols WW, O'Rourke MF, editors. McDonald's blood flow in arteries: theoretical, experimental and clinical principles. 5th ed. Oxford: Oxford University Press; 2005. pp. 375-378, 396-397.
11. O'Rourke MF. In: Safar ME, O'Rourke MF, editors. Handbook of hypertension, arterial stiffness in hypertension, vol. 23. Amsterdam: Elsevier; 2006. pp. 3-20.
12. O'Rourke MF, Nichols WW. Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension. Hypertension 2005; 45:652-658.
13. Najjar SS, Scuteri A, Lakatta EG. Arterial aging: is it an immuable cardiovascular risk factor? Hypertension 2005; 46:454-462.
14. O'Rourke MF, Avolio AP, Lauren PD, Yong J. Age related changes of elastic lamellae in the human thoracic aorta. J Am Coll Cardiol 1987; 9:53-58.
15. Blumenthal HT, Lansing AI, Wheeler PA. Calcification of human aorta and its relation to intimal atherosclerosis, aging and disease. Am J Pathol 1994; 20:665-687.
16. Avolio AO, Chen SG, Wang RP, et al. Effects of aging on changing arterial compliance and left ventricular load in a northern Chinese urban community. Circulation 1983; 68:50-58.
17. Nichols WW, Avolio AP, Kelly RP, O'Rourke MF. Effects of age and of hypertension on wave travel and reflections. In: O'Rourke M, Safar M, Dzau V, editors. Arterial vasodilatation: mechanisms and therapy. London: Edward Arnold; 1993. pp. 23-40.
18. Mitchell GF, Vita JA, Larson MG, et al. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness. The Framingham Heart Study. Circulation 2005; 112:3722-3728.
19. Verhave JC, Fesler P, du Callar G, et al. Elevated pulse pressure is associated with low renal function in elderly patients with isolated systolic hypertension. Hypertension 2005; 45:586-591.
20. Hanon O, Haulon S, Lenoir H, et al. Relationship between arterial stiffness and cognitive function in elderly subjects with complaints of memory loss. Stroke 2005;36:2193-2197.
21. O'Rourke MF, Safar ME. Relationship between aortic stiffening and micro-vascular disease in brain and kidney. Cause and logic of therapy. Hypertension 2005; 46:200-204.
22. Laurent S, Boutouyrie P, Lacolley P. Structural and genetic bases of arterial stiffness. Hypertension 2005; 45:1050-1055.
23. Vlachopoulos C, Dima I, Aznaouridis C, et al. Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals. Circulation 2005; 112:2193-2200.
24. Roman MJ, Devereux RB, Schwartz JE, et al. Aortic stiffness in chronic inflammatory diseases. Hypertension 2005; 46:194-199.
25. Maki-Petaja K, Hall F, Booth A, et al. Rheumatoid arthritis is associated with increased aortic pulse-wave velocity, which is reduced by antitumor necrosis factor-alpha therapy. Circulation 2006; 114:1185-1192.
26. Amabile N, Guérin AP, Leroyer A, et al. Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure. J Am Soc Nephrol 2005; 16:3381-3388.
27. Yasmin, McEniery CM, O'Shaugnessy KM, et al. Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals. Arterioscler Thomb Vasc Biol 2005; 25:372-378.
28. Zhu L, Vranckx R, Kauh Van Kien P, et al. Mutation in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. Nat Genet 2006; 38:343-349.
29. DeLoach SS, Townsend RR. Vascular stiffness: its measurement and significance for epidemiologic and outcome studies. Clin J Am Soc Nephrol 2008; 3:184-192.
30. Pannier B, Guérin AP, Marchais SJ, et al. Stiffness of capacitive and conduit arteries: prognostic significance for end-stage renal disease patients. Hypertension 2006; 47:592-596.
31. Kimoto E, Shoji T, Shinohara K, et al. Regional arterial stiffness in patients with type 2 diabetes and chronic kidney disease. J Am Soc Nephrol 2006; 17:2245-2252.
32. Schillaci G, Pirro M, Mannarino MR, Pucci G, et al. Relation between renal function within the normal range and central and peripheral arterial stiffness in hypertension. Hypertension 2006; 48:616-621.
33. Zoungas S, Cameron JD, Kerr PG, et al. Association of intima-media carotid thickness and indices of arterial stiffness with cardiovascular disease outcome in CKD. Am J Kidney Dis 2007; 50:622-630.
34. Frimodt-Moller M, Nielsen AH, Kamper AL, Strandgaard S. Reproducibility of pulse-wave velocity determination in chronic kidney disease. Nephrol Dial Transplant 2008; 23:594-600.
35. Hoeks AP, Brands P, Smeets FA, Reneman RS. Assessment of the distensibility of superficial arteries. Ultrasound Med Biol 1990; 16:121-128.
36. Tardy Y, Meister JJ, Perret F, et al. Noninvasive estimate of the mechanical properties of peripheral arteries from ultrasonic and photoplethysmographic measurements. Clin Phys Physiol Meas 1991; 12:39-54.
37. Lemogoum D, Flores G, Van den Abeele W, et al. Validity of pulse pressure and augmentation index as surrogate measures of arterial stiffness during beta-adrenergic stimulation. J Hypertens 2004; 22:511-517.
38. London GM, Guérin AP, Marchais SJ, et al. Cardiac and arterial interactions in end-stage renal disease. Kidney Int 1996; 50:600-608.
39. Verbeke FH, Agharazii M, Boutouyrie P, et al. Local shear stress and brachial artery functions in end-stage renal disease. J Am Soc Nephrol 2007; 18: 621-628.
40. Mourad JJ, Girerd X, Boutouyrie P, et al. Increased stiffness of radial artery wall material in end-stage renal disease. Hypertension 1997; 30:1425-1430.
41. Laurent S, Girerd X, Mourad JJ, et al. Elastic modulus of the radial artery wall material is not increased in patients with essential hypertension. Arterioscler Thromb 1994; 14:1223-1231.
42. Ibels LS, Alfrey AL, Huffer WE, et al. Arterial calcification and pathology in uremic patients undergoing dialysis. Am J Med 1979; 66:790-796.
43. Amann K, Wolf B, Nichols C, Törnig J, et al. Aortic changes in experimental renal failure: hyperplasia or hypertrophy of smooth muscle cells? Hypertension 1997; 29:770-775.
44. Dammers R, Tordoir JM, Welten RJ, et al. The effect of chronic flow changes on brachial artery diameter and shear stress in arteriovenous fistulas for hemodialysis. Int J Artif Organs 2002; 69:124-128.
45. Cunningham KS, Gotlieb AI. The role of shear stress in the pathogenesis of atherosclerosis. Lab Invest 2005; 85:9-23.
46. Yamawaki H, Pan S, Lee RT, Berk BC. Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial calls. J Clin Invest 2005; 115:733-738.
47. Boulanger CM, Amabile N, Guerin AP, et al. In vivo shear stress determines circulating levels of endothelial microparticles in end-stage renal disease. Hypertension 2007; 49:1-7.
48. Briet M, Bozec E, Laurent S, et al. Arterial stiffness and enlargement in mild-to-moderate chronic kidney disease. Kidney Int 2006; 69:350-357.
49. Wang MC, Tsai WC, Chen JY, Huang JJ. Stepwise increase in arterial stiffness corresponding with the stages of chronic kidney disease. Am J Kidney Dis 2005; 45:494-501.
50. Taal MW, Sigrist MK, Fakis A, et al. Markers of arterial stiffness are risk factors for progression to end-stage renal disease among patients with chronic kidney disease stages 4 and 5. Nephron Clin Pract 2007; 107:177-181.
51. Scholze A, Wittstock A, Zidek W, Tepel M. Impaired vascular reactivity in patients with chronic kidney disease. Am J Nephrol 2008; 28:218-223.
52. Covic A, Mardare N, Gusbeth-Tatomir P, et al. Increased arterial stiffness in children on haemodialysis. Nephrol Dial Transplant 2006; 21:729-735.
53. Bakiler AR, Yavascan O, Harputuoglu N, et al. Evaluation of aortic stiffness in children with chronic renal failure. Pediatr Nephrol 2007; 22:1911-1919.
54. Kis E, Cseprekál O, Horváth Z, et al. Pulse wave velocity in end-stage renal disease: influence of age and body dimension. Pediatr Res 2008; 63:95-98.
55. Covic A, Golgsmith DJ, Florea L, et al. The influence of dialytic modality on arterial stiffness, pulse wave reflections, and vascular function. Perit Dial Int 2004; 24:365-372.
56. Covic A, Goldsmith DJ, Gusbeth-Tatomir P, et al. Successful renal transplantation decreases aortic stiffness and increases vascular reactivity in dialysis patients. Transplantation 2003; 76:1573-1577.
57. Westhoff TH, Straub-Hohenbleicher H, Basdorf M, et al. Time-dependent effect of cadaveric renal transplantation on arterial compliance in patients with end-stage renal disease. Transplantation 2006; 81:1410-1414.
58. Kneifel M, Scholze A, Burkert A, et al. Impaired renal allograft function is associated with increased arterial stiffness in renal transplant recipients. Am J Transplant 2006; 6:1624-1630.
59. Verbeke FH, Van Blessen W, Peeters P, et al. Arterial stiffness and wave reflections in renal transplant recipients. Nephrol Dial Transplant 2007; 22:3021-3027.
60. Delahousse M, Chaignon M, Mesnard L, et al. Aortic stiffness of kidney transplant recipients correlates with donor age. J Am Soc Nephrol 2008; 19:798-805. In this study, authors demonstrated the role of kidney donor age on evolution of aortic stiffening which progresses in recipients of older kidneys grafts.
61. Mourad JJ, Pannier B, Blacher J, et al. Creatinine clearance, pulse wave velocity, carotid compliance and essential hypertension. Kidney Int 2001; 59:1834-1841.
62. Hermans MM, Henry R, Dekker JM, et al. Estimated glomerular filtration rate and urinary albumin excretion are independently associated with greater arterial stiffness: the Hoorn Study. J Am Soc Nephrol 2007; 18:1942-1952.
63. Yoshida M, Tomiyama H, Yamada J, et al. Relationship among renal function loss within the normal or mildly impaired range, arterial stiffness, inflammation, and oxidative stress. Clin J Am Soc Nephrol 2007; 2:1118-1124.
64. Mulè G, Cottone S, Cusimano P, et al. Inverse relationship between ambulatory arterial stiffness index and glomerular filtration rate in arterial hypertension. Am J Hypertens 2008; 21:35-40.
65. Nakagawa N, Takahashi F, Chinda J, et al. A newly estimated glomerular filtration rate is independently associated with arterial stiffness in Japanese patients. Hypertens Res 2008; 31:193-201.
66. Kawamoto R, Kohara K, Tabara Y, et al. An association between decreased estimated glomerular filtration rate and arterial stiffness. Intern Med 2008; 47:593-598.
67. London GM, Guérin AP, Verbeke FH, et al. Mineral metabolism and arterial functions in end-stage renal disease: potential role of 25-hydroxyvitamin D deficiency. J Am Soc Nephrol 2007; 18:613-620.
68. Guérin AP, London GM, Marchais SJ, Métivier F. Arterial stiffening and vascular calcifications in end-stage renal disease. Nephrol Dial Transplant 2000; 15:1014-1021.
69. Blacher J, Guérin AP, Pannier B, et al. Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease. Hypertension 2001; 38:938-942.
70. Haydar AA, Covic A, Colhoun H, et al. Coronary artery calcification and aortic pulse wave velocity in chronic kidney disease patients. Kidney Int 2004; 65:1790-1794.
71. Raggi P, Bellasi A, Ferramosca E, et al. Association of pulse wave velocity with vascular and valvular calcification in hemodialysis patients. Kidney Int 2007; 71:802-807.
72. Sigrist MK, Taal MW, Bungay P, McIntyre CW. Progressive vascular calcification over 2 years is associated with arterial stiffening and increased mortality in patients with stages 4 and 5 chronic kidney disease. Clin J Am Soc Nephrol 2007; 2:1241-1248.
73. Braun J, Oldendorf M, Moshage W, et al. Electron-beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients. Am J Kidney Dis 1996; 27:394-401.
74. Goodman WG, Goldin J, Kuizon BD, et al. Coronary artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med 2000; 342:1478-1483.
75. Davies MR, Hruska KA. Pathophysiological mechanisms of vascular calcification in end-stage renal disease. Kidney Int 2001; 60:472-479.
76. Moe SM, Chen NX. Mechanisms of vascular calcification in chronic kidney disease. J Am Soc Nephrol 2008; 19:213-216.
77. Mori K, Emoto M, Araki T, et al. Association of serum fetuin-A with carotid arterial stiffness. Clin Endocrinol 2007; 66:246-250.
78. Hermans MM, Brandenburg V, Ketteler M, et al. Study on the relationship of serum fetuin-A concentration with aortic stiffness in patients on dialysis. Nephrol Dial Transplant 2006; 21:1293-1299.
79. Kuzniar J, Porazko T, Klinger M. Relationship between fetuin-A concentration, elevated level of inflammatory markers, and arterial wall stiffness in end-stage renal disease. J Ren Nutr 2008; 18:83-86.
80. Hak AE, Pols HA, van Hemert AM, et al. Progression of aortic calcification is associated with metacarpal bone loss during menopause: a population-based longitudinal study. Arterioscler Thromb Vasc Biol 2000; 20:1926-1931.
81. Kiel DP, Kauppila LI, Cupples LA, et al. Bone loss and the progression of abdominal aortic calcification over a 25-year period: the Framingham Heart Study. Calcif Tissue Int 2001; 68:271-276.
82. Sumimo H, Ichikawa S, Kasama S, et al. Elevated arterial stiffness in post-menopausal women with osteoporosis. Maturitas 2006; 55:212-218.
83. Raggi P, Bellasi A, Ferramosca E, et al. Pulse wave velocity is inversely related to vertebral bone density in hemodialysis patients. Hypertension 2007; 49:1278-1284.
84. Joki N, Hase H, Shirataka M, et al. Calcaneal osteopenia is a new marker for arterial stiffness in chronic hemodialysis patients. Am J Nephrol 2005; 25:196-202.
85. London GM, Marty C, Marchais SJ, et al. Arterial calcifications and bone histomorphometry in end-stage renal disease. J Am Soc Nephrol 2004; 15:1943-1951.
86. Toussaint ND, Lau KK, Strauss BJ, et al. Association between vascular calcification, arterial stiffness and bone mineral density in chronic kidney disease. Nephrol Dial Transplant 2008; 23:586-593.
87. London GM, Marchais SJ, Guérin AP, et al. Association of bone activity, • calcium load, aortic stiffness, and calcifications in ESRD. J Am Soc Nephrol 2008. [Epub ahead of print] This study indicates that in patients with ESRD a significant and independent interaction exists between bone activity and aortic stiffness, suggesting the existence of an independent bone-arterial cross-talk.
88. Lee NK, Sowa H, Hinoi E, et al. Endocrine regulation of energy metabolism by the skeleton. Cell 2007; 130:456-469. In a mouse model, authors tested the hypothesis that bone exerts a control on energy homeostasis by genes expressed in osteoblasts. They showed that osteocalcin stimulates insulin expression in β cells, improves insulin sensitivity, and increases secretion of adiponectin.
89. Oshima K, Nampei A, Matsuda M, et al. Adiponectin increases bone mass by suppressing osteoclasts and activating osteoblasts. Biochem Biophys Res Commun 2005; 331:520-526.
90. Timms PM, Mannan M, Hitman GA, et al. Circulating MMP9, vitamin D and variation in the TIMP-1 response with vitamin D receptor genotype: mechanisms for inflammatory damage in chronic disorders? Q J Med 2002; 95:787-796.
91. Braam LAJL, Hoeks APG, Brouns F, et al. Beneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: a follow-up study. Thromb Haemost 2004; 91:373-380.
92. Agarwal R. Antihypertensive agents and arterial stiffness: relevance to reducing cardiovascular risk in the chronic kidney disease patient. Curr Opin Nephrol Hypertens 2007; 16:409-415.
93. Guerin A, Blacher J, Pannier B, et al. Impact of aortic stiffness attenuation on survival of patients in end-stage renal disease. Circulation 2001; 103:987-992.
94. Block GA, Spiegal DM, Ehrlich J, et al. Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis. Kidney Int 2005; 68:1815-1824.