Specific cellular immune response in hepatitis E patients

Intervirology

Volumn 51, Issue 5, 2009, Pages 322-327

  Wu, Ting ^a   Zhang, Jun ^a   Su, Zhi Jun ^c   Liu, Jia Jun ^b   Wu, Xiao Lu ^a,b   Lin, Chun Xin ^a   Ou, Shan Hai ^a   Yan, Qiang ^a   Shih, J Wai Kuo ^a   Xia, Ning Shao ^a  

^a XIAMEN UNIVERSITY   (China)

^b Xiamen First Hospital   (China)

^c First Hospital of Quanzhou   (China)

Author keywords

Cellular immune response; Enzyme linked immunosorbent spot assay; Hepatitis E

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINO ACID; CAPSID PROTEIN; IMMUNOGLOBULIN M ANTIBODY; VIRUS RNA;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIBODY TITER; ARTICLE; BLOOD EXAMINATION; BLOOD SAMPLING; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONVALESCENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS E; HEPATITIS E VIRUS; HUMAN; IMMUNOSTIMULATION; LIVER FUNCTION; MALE; MEDICAL EXAMINATION; OPEN READING FRAME; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA VIRUS; T LYMPHOCYTE;

ADULT; AGED; ANIMALS; ANTIBODIES, VIRAL; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATITIS E; HUMANS; IMMUNOGLOBULIN M; LIVER; LIVER FUNCTION TESTS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; T-LYMPHOCYTES;

HEPATITIS E VIRUS; MIRIDAE;

EID: 56149109070     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000172627     Document Type: Article

References (20)

1. Worm HC, van der Poel WH, Brandstatter G: Hepatitis E: an overview. Microbes Infect 2002;4:657-666.
2. Chau TN, Lai ST, Tse C, Ng TK, Leung VK, Lim W, Ng MH: Epidemiology and clinical features of sporadic hepatitis E as compared with hepatitis A. Am J Gastroenterol 2006;101:292-296.
3. Takahashi K, Kang JH, Ohnishi S, Hino K, Miyakawa H, Miyakawa Y, Maekubo H, Mishiro S: Full-length sequences of six hepatitis E virus isolates of genotypes III and IV from patients with sporadic acute or fulminant hepatitis in Japan. Intervirology 2003;46:308-318.
4. Kumar A, Beniwal M, Kar P, Sharma JB, Murthy NS: Hepatitis E in pregnancy. Int J Gynaecol Obstet 2004;85:240-244.
5. Pal R, Aggarwal R, Naik SR, Das V, Das S, Naik S: Immunological alterations in pregnant women with acute hepatitis E. J Gastroenterol Hepatol 2005;20:1094-1101.
6. Amon JJ, Drobeniuc J, Bower WA, Magana JC, Escobedo MA, Williams IT, Bell BP, Armstrong GL: Locally acquired hepatitis E virus infection, El Paso, Texas. J Med Virol 2006;78:741-746.
7. Masuda JI, Yano K, Tamada Y, Takii Y, Ito M, Omagari K, Kohno S: Acute hepatitis E of a man who consumed wild boar meat prior to the onset of illness in Nagasaki, Japan. Hepatol Res 2005;31:178-183.
8. Schlauder GG, Desai SM, Zanetti AR, Tassopoulos NC, Mushahwar IK: Novel hepatitis E virus (HEV) isolates from Europe: evidence for additional genotypes of HEV. J Med Virol 1999;57:243-251.
9. Lewis H, Morgan D, Ijaz S, Boxall E: Indigenous hepatitis E virus infection in England and Wales. BMJ 2006;332:1509-1510.
10. Emerson SU, Purcell RH: Hepatitis E virus. Rev Med Virol 2003;13:145-154.
11. van Cuyck-Gandre H, Cockman-Thomas R, Caudill JD, Asher LS, Armstrong KL, Hauroeder B, Clements NJ, Binn LN, Longer CF: Experimental African HEV infection in cynomolgus macaques (Macaca fascicularis). J Med Virol 1998;55:197-202.
12. Naik S, Aggarwal R, Naik SR, Dwivedi S, Talwar S, Tyagi SK, Duhan SD, Coursaget P: Evidence for activation of cellular immune responses in patients with acute hepatitis E. Indian J Gastroenterol 2002;21:149-152.
13. Zhang J, Ge SX, Huang GY, Li SW, He ZQ, Wang YB, Zheng YJ, Gu Y, Ng MH, Xia NS: Evaluation of antibody-based and nucleic acid-based assays for diagnosis of hepatitis E virus infection in a rhesus monkey model. J Med Virol 2003;71:518-526.
14. Li SW, Zhang J, He ZQ, Gu Y, Liu RS, Lin J, Chen YX, Ng MH, Xia NS: Mutational analysis of essential interactions involved in the assembly of hepatitis E virus capsid. J Biol Chem 2005;280:3400-3406.
15. Zhang J, Gu Y, Ge SX, Li SW, He ZQ, Huang GY, Zhuang H, Ng MH, Xia NS: Analysis of hepatitis E virus neutralization sites using monoclonal antibodies directed against a virus capsid protein. Vaccine 2005;23:2881-2892.
16. Wu T, Wu XL, Ou SH, Lin CX, Cheng T, Li SW, Ng MH, Zhang J, Xia NS: Difference of T cell and B cell activation in two homologous proteins with similar antigenicity but great distinct immunogenicity. Mol Immunol 2007;44:3261-3266.
17. Missale G, Bertoni R, Lamonaca V, Valli A, Massari M, Mori C, Rumi MG, Houghton M, Fiaccadori F, Ferrari C: Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J Clin Invest 1996;98:706-714.
18. Aggarwal R, Kamili S, Spelbring J, Krawczynski K: Experimental studies on subclinical hepatitis E virus infection in cynomolgus macaques. J Infect Dis 2001;184:1380-1385.
19. Banas B, Tausch U, Hofstadter F, Woenckhaus M, Pietrzyk MC, Riegger GAJ, Boehm S, Kramer BK: Infection with hepatitis E virus: first report of a chronic case and molecular characterization of the virus. J Clin Virol 2006;36:S162.
20. Aggarwal R, Shukla R, Jameel S, Agrawal S, Puri P, Gupta VK, Patil AP, Naik S: T-cell epitope mapping of ORF2 and ORF3 proteins of human hepatitis E virus. J Viral Hepat 2007;14:283-292.