Keratitis by Acanthamoeba triangularis: Report of cases and characterization of isolates

Korean Journal of Parasitology

Volumn 46, Issue 3, 2008, Pages 157-164

  Xuan, Ying Hua ^a   Chung, Byung Suk ^a   Hong, Yeon Chul ^a   Kong, Hyun Hee ^a   Hahn, Tae Won ^b   Chung, Dong Il ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Apgujung St Mary's Eye Center   (South Korea)

Author keywords

Acanthamoeba; Acanthamoeba triangularis; Contact lenses; Keratitis

Indexed keywords

ANTIAMEBIC AGENT; ANTIBIOTIC AGENT; CEPHALOSPORIN; DNA 16S; DNA 18S; GENTAMICIN; ITRACONAZOLE; MITOCHONDRIAL DNA; POLY(HEXAMETHYLENEBIGUANIDE); RESTRICTION ENDONUCLEASE; RIBOSOME DNA; ANTIPROTOZOAL AGENT; BIGUANIDE DERIVATIVE; PROTOZOAL DNA; RNA 16S; RNA 18S;

ACANTHAMOEBA; ACANTHAMOEBA CASTELLANII; ACANTHAMOEBA KERATITIS; ACANTHAMOEBA TRIANGULARIS; ADOLESCENT; ADULT; ARTICLE; CASE REPORT; CONJUNCTIVAL HYPEREMIA; CONTACT LENS; CONTROLLED STUDY; CORNEA OPACITY; CORNEA ULCER; CYST (RESTING STAGE); DIFFERENTIAL DIAGNOSIS; DNA SEQUENCE; EYE PAIN; FEMALE; HUMAN; KERATITIS; KOREA; LACRIMATION; MALE; MICROBIAL MORPHOLOGY; MIXED INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOKERATOLOGY; PARASITE ISOLATION; PHASE CONTRAST MICROSCOPY; PHOTOPHOBIA; PHYLOGENY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RESTRICTION MAPPING; SLIT LAMP; STRAIN IDENTIFICATION; VISUAL ACUITY; VISUAL DISORDER; ANIMAL; CLASSIFICATION; GENETICS; ISOLATION AND PURIFICATION; PARASITOLOGY;

ACANTHAMOEBA; ACANTHAMOEBA TRIANGULARIS;

ACANTHAMOEBA; ACANTHAMOEBA KERATITIS; ADOLESCENT; ADULT; ANIMALS; ANTIPROTOZOAL AGENTS; BIGUANIDES; DNA, MITOCHONDRIAL; DNA, PROTOZOAN; FEMALE; HUMANS; MALE; PHYLOGENY; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, RIBOSOMAL, 16S; RNA, RIBOSOMAL, 18S;

EID: 56149083448     PISSN: 00234001     EISSN: 17380006     Source Type: Journal    
DOI: 10.3347/kjp.2008.46.3.157     Document Type: Article

References (34)

1. Marciano-Cabral F, Cabral G. Acanthamoeba spp. as agents of disease in humans. Clin Microbiol Rev 2003; 16: 273-307.
2. Moore MB, McCulley JP, Newton C, Cobo LM, Foulks GN, O'Day DM, Johns KJ, Driebe WT, Wilson LA, Epstein RJ, et al. Acanthamoeba keratitis. A growing problem in soft and hard contact lens wearers. Ophthalmology 1987; 94: 1654-1661.
3. Illingworth CD, Cook SD. Acanthamoeba keratitis. Surv Ophthalmol 1998; 42: 493-508.
4. Schaumberg DA, Snow KK, Dana MR. The epidemic of Acanthamoeba keratitis: where do we stand? Cornea 1998; 17: 3-10.
5. Yu HS, Kong HH, Kim SY, Hahn YH, Hahn TW, Chung DI. Laboratory investigation of Acanthamoeba lugdunensis from patients with keratitis. Invest Ophthalmol Vis Sci 2004; 45: 1418-1426.
6. Ledee DR, Hay J, Byers TJ, Seal DV, Kirkness CM. Acanthamoeba griffini. Molecular characterization of a new corneal pathogen. Invest Ophthalmol Vis Sci 1996; 37: 544-550.
7. Pussard M, Pons R. Morphologie de la paroi kystique et taxonomie du gene Acanthamoeba (Protozoa, Amoebida). Protistologica 1977; 13: 557-598.
8. Chung DI, Kong HH, Yu HS, Oh YM, Yee ST, Lim YJ. Biochemical and molecular characterization of a strain KA/S2 of Acanthamoeba castellanii isolated from Korean soil. Korean J Parasitol 1996; 34: 79-85.
9. Kong HH, Shin JY, Yu HS, Kim J, Hahn TW, Hahn YH, Chung DI. Mitochondrial DNA restriction fragment length polymorphism (RFLP) and 18S small-subunit ribosomal DNA PCR-RFLP analyses of Acanthamoeba isolated from contact lens storage cases of residents in southwestern Korea. J Clin Microbiol 2002; 40: 1199-1206.
10. Stothard DR, Schroeder-Diedrich JM, Awwad MH, Gast RJ, Ledee DR, Rodriguez-Zaragoza S, Dean CL, Fuerst PA, Byers TJ. The evolutionary history of the genus Acanthamoeba and the identification of eight new 18S rRNA gene sequence types. J Eukaryot Microbiol 1998; 45: 45-54.
11. Ledee DR, Booton GC, Awwad MH, Sharma S, Aggarwal RK, Niszl IA, Markus MB, Fuerst PA, Byers TJ. Advantages of using mitochondrial 16S rDNA sequences to classify clinical isolates of Acanthamoeba. Invest Ophthalmol Vis Sci 2003; 44: 1142-1149.
12. Chung DI, Yu HS, Hwang MY, Kim TH, Kim TO, Yun HC, Kong HH. Subgenus classification of Acanthamoeba by riboprinting. Korean J Parasitol 1998; 36: 69-80.
13. Yu HS, Hwang MY, Kim TO, Yun HC, Kim TH, Kong HH, Chung DI. Phylogenetic relationships among Acanthamoeba spp. based on PCR-RFLP analyses of mitochondrial small subunit rRNA gene. Korean J Parasitol 1999; 37: 181-188.
14. Yagita K, Endo T. Restriction enzyme analysis of mitochondrial DNA of Acanthamoeba strains in Japan. J Protozool 1990; 37: 570-575.
15. Kong HH, Chung DI. PCR and RFLP variation of conserved region of small subunit ribosomal DNA among Acanthamoeba isolates assigned to either A. castellanii or A. polyphaga. Korean J Parasitol 1996; 34: 127-134.
16. Gunderson JH, Sogin ML. Length variation in eukaryotic rRNAs: small subunit rRNAs from the protists Acanthamoeba castellanii and Euglena gracilis. Gene 1986; 44: 63-70.
17. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol 1990; 215: 403-410.
18. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997; 25: 4876-4882.
19. Naginton J, Watson PG, Playfair TJ, McGill J, Jones BR, Steele AD. Amoebic infection of the eye. Lancet 1974; 2: 1537-1540.
20. Jones DB, Visvesvara GS, Robinson NM. Acanthamoeba polyphaga keratitis and Acanthamoeba uveitis associated with fatal meningoencephalitis. Trans Ophthalmol Soc U K 1975; 95: 221-232.
21. Walochnik J, Haller-Schober E, Kolli H, Picher O, Obwaller A, Aspock H. Discrimination between clinically relevant and non-relevant Acanthamoeba strains isolated from contact lens-wearing keratitis patients in Austria. J Clin Microbiol 2000; 38: 3932-3936.
22. Walochnik J, Obwaller A, Aspock H. Correlations between morphological, molecular biological, and physiological characteristics in clinical and nonclinical isolates of Acanthamoeba spp. Appl Environ Microbiol 2000; 66: 4408-4413.
23. Yu HS, Choi KH, Kim HK, Kong HH, Chung DI. Genetic analyses of Acanthamoeba isolates from contact lens storage cases of students in Seoul, Korea. Korean J Parasitol 2001; 39: 161-170.
24. Lee SM, Choi YJ, Ryu HW, Kong HH, Chung DI. Species identification and molecular characterization of Acanthamoeba isolated from contact lens paraphernalia. Korean J Ophthalmol 1997; 11: 39-50.
25. Stevens AR, Willaert E. Drug sensitivity and resistance of four Acanthamoeba species. Trans R Soc Trop Med Hyg 1980; 74: 806-808.
26. Jongwutiwes S, Pariyakanok L, Charoenkorn M, Yagita K, Endo T. Heterogeneity in cyst morphology within isolates of Acanthamoeba from keratitis patients in Thailand. Trop Med Int Health 2000; 5: 335-340.
27. Seal DV. Acanthamoeba keratitis update-incidence, molecular epidemiology and new drugs for treatment. Eye 2003; 17: 893-905.
28. Kong HH, Park JH, Chung DI. Interstrain polymorphisms of isoenzyme profiles and mitochondrial DNA fingerprints among seven strains assigned to Acanthamoeba polyphaga. Korean J Parasitol 1995; 33: 331-340.
29. Xuan YH, Yu HS, Jeong HJ, Seol SY, Chung DI, Kong HH. Molecular characterization of bacterial endosymbionts of Acanthamoeba isolates from infected corneas of Korean patients. Korean J Parasitol 2007; 45: 1-9.
30. Schuster FL, Visvesvara GS. Free-living amoebae as opportunistic and non-opportunistic pathogens of humans and animals. Int J Parasitol 2004; 34: 1001-1027.
31. Liu H, Moon EK, Yu HS, Jeong HJ, Hong YC, Kong HH, Chung DI. Evaluation of taxonomic validity of four species of Acanthamoeba: A. divionensis, A. paradivionensis, A. mauritaniensis, and A. rhysodes, inferred from molecular analyses. Korean J Parasitol 2005; 43: 7-13.
32. Lee JS, Hahn TW, Choi SH, Yu HS, Lee JE. Acanthamoeba keratitis related to cosmetic contact lenses. Clin Experiment Ophthalmol 2007; 35: 775-777.
33. Lee JE, Hahn TW, Oum BS, Choi HY, Yu HS, Lee JS. Acanthamoeba keratitis related to orthokeratology. Int Ophthalmol 2007; 27: 45-49.
34. Ibrahim YW, Boase DL, Cree IA. Factors affecting the epidemiology of Acanthamoeba keratitis. Ophthalmic Epidemiol 2007; 14: 53-60.