The anti-inflammatory effect of neuropeptide Y (NPY) in rats is dependent on dipeptidyl peptidase 4 (DP4) activity and age

Peptides

Volumn 29, Issue 12, 2008, Pages 2179-2187

  Dimitrijević, Mirjana ^a   Stanojević, Stanislava ^a   Mitić, Katarina ^a   Kuštrimović, Nataša ^a   Vujić, Vesna ^b   Miletić, Tatjana ^a   Kovačević Jovanović, Vesna ^a  

^a Immunology Research Center Belgrade   (Yugoslavia)

^b UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Dark Agouti rats; Dipeptidyl peptidase 4 (DP4); Inflammation; Macrophages; Neuropeptide Y (NPY); Nitric oxide

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; NEUROPEPTIDE Y; NEUROPEPTIDE Y1 RECEPTOR; NEUROPEPTIDE Y5 RECEPTOR;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; MACROPHAGE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PAW EDEMA; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; ANTIGENS, CD26; CELLS, CULTURED; DEXAMETHASONE; EDEMA; INFLAMMATION; MACROPHAGES, PERITONEAL; MALE; NEUROPEPTIDE Y; NITRIC OXIDE; PEPTIDE FRAGMENTS; RATS; RECEPTORS, NEUROPEPTIDE Y;

AGOUTI; RATTUS;

EID: 56049125933     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2008.08.017     Document Type: Article

References (55)

1. Ahmed A.A., Wahbi A., Nordlind K., Kharazmi A., Sundqvist K.G., Mutt V., et al. In vitro Leishmania major promastigote-induced macrophage migration is modulated by sensory and autonomic neuropeptides. Scand J Immunol 48 (1998) 79-85
2. Bauvois B., Sanceau J., and Wietzerbin J. Human U937 cell surface peptidase activities: characterization and degradative effect on tumor necrosis factor-alpha. Eur J Immunol 22 (1992) 923-930
3. Bedoui S., Kawamura N., Straub R.H., Pabst R., Yamamura T., and von Horsten S. Relevance of neuropeptide Y for the neuroimmune crosstalk. J Neuroimmunol 134 (2003) 1-11
4. Bedoui S., Kromer A., Gebhardt T., Jacobs R., Raber K., Dimitrijevic M., et al. Neuropeptide Y receptor-specifically modulates human neutrophil function. J Neuroimmunol 195 (2008) 88-95
5. Bedoui S., Kuhlmann S., Nave H., Drube J., Pabst R., and von Horsten S. Differential effects of neuropeptide Y (NPY) on leukocyte subsets in the blood: mobilization of B-1-like B-lymphocytes and activated monocytes. J Neuroimmunol 117 (2001) 125-132
6. Bedoui S., Miyake S., Lin Y., Miyamoto K., Oki S., Kawamura N., et al. Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo. J Immunol 171 (2003) 3451-3458
7. Bedoui S., Miyake S., Straub R.H., von Horsten S., and Yamamura T. More sympathy for autoimmunity with neuropeptide Y?. Trends Immunol 25 (2004) 508-512
8. Cabrele C., Langer M., Bader R., Wieland H.A., Doods H.N., Zerbe O., et al. The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats. J Biol Chem 275 (2000) 36043-36048
9. Cavallotti D., Artico M., Iannetti G., and Cavallotti C. Occurrence of adrenergic nerve fibers in human thymus during immune response. Neurochem Int 40 (2002) 211-221
10. Chanez P., Springall D., Vignola A.M., Moradoghi-Hattvani A., Polak J.M., Godard P., et al. Bronchial mucosal immunoreactivity of sensory neuropeptides in severe airway diseases. Am J Respir Crit Care Med 158 (1998) 985-990
11. Corsini E., Battaini F., Lucchi L., Marinovich M., Racchi M., Govoni S., et al. A defective protein kinase C anchoring system underlying age-associated impairment in TNF-alpha production in rat macrophages. J Immunol 163 (1999) 3468-3473
12. De la Fuente M., Bernaez I., Del Rio M., and Hernanz A. Stimulation of murine peritoneal macrophage functions by neuropeptide Y and peptide YY. Involvement of protein kinase C. Immunology 80 (1993) 259-265
13. De la Fuente M., Del Rio M., and Medina S. Changes with aging in the modulation by neuropeptide Y of murine peritoneal macrophage functions. J Neuroimmunol 116 (2001) 156-167
14. De la Fuente M., Medina S., Del Rio M., Ferrandez M.D., and Hernanz A. Effect of aging on the modulation of macrophage functions by neuropeptides. Life Sci 67 (2000) 2125-2135
15. Dimitrijevic M., Laban O., Djuric V.J., Stanojevic S., Miletic T., Kovacevic-Jovanovic V., et al. Behavior and severity of adjuvant arthritis in four rat strains. Brain Behav Immun 15 (2001) 255-265
16. Dimitrijevic M., Stanojevic S., Micic S., Vujic V., Kovacevic-Jovanovic V., Mitic K., et al. Neuropeptide Y (NPY) modulates oxidative burst and nitric oxide production in carrageenan-elicited granulocytes from rat air pouch. Peptides 27 (2006) 3208-3215
17. Dimitrijevic M., Stanojevic S., Vujic V., Beck-Sickinger A., and von Horsten S. Neuropeptide Y and its receptor subtypes specifically modulate rat peritoneal macrophage functions in vitro: counter regulation through Y1 and Y2/5 receptors. Regul Pept 124 (2005) 163-172
18. Dimitrijevic M., Stanojevic S., Vujic V., Kovacevic-Jovanovic V., Beck-Sickinger A., Demuth H., et al. Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPY Y1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26). J Neuroimmunol 129 (2002) 35-42
19. Durinx C., Neels H., Van der Auwera J.C., Naelaerts K., Scharpe S., and De Meester I. Reference values for plasma dipeptidyl-peptidase IV activity and their association with other laboratory parameters. Clin Chem Lab Med 39 (2001) 155-159
20. Ekblad E., Edvinsson L., Wahlestedt C., Uddman R., Hakanson R., and Sundler F. Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers. Regul Pept 8 (1984) 225-235
21. Frerker N., Wagner L., Wolf R., Heiser U., Hoffmann T., Rahfeld J.U., et al. Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4. Peptides 28 (2007) 257-268
22. Fujiwara H., Kurihara N., Hirata K., Ohta K., Kanazawa H., and Takeda T. Effect of neuropeptide Y on human bronchus and its modulation of neutral endopeptidase. J Allergy Clin Immunol 92 (1993) 89-94
23. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S., and Tannenbaum S.R. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 126 (1982) 131-138
24. Harle P., Straub R.H., Wiest R., Mayer A., Scholmerich J., Atzeni F., et al. Increase of sympathetic outflow measured by neuropeptide Y and decrease of the hypothalamic-pituitary-adrenal axis tone in patients with systemic lupus erythematosus and rheumatoid arthritis: another example of uncoupling of response systems. Ann Rheum Dis 65 (2006) 51-56
25. Hassani H., Lucas G., Rozell B., and Ernfors P. Attenuation of acute experimental colitis by preventing NPY Y1 receptor signaling. Am J Physiol Gastrointest Liver Physiol 288 (2005) G550-G556
26. Hernanz A., Medina S., de Miguel E., and Martin-Mola E. Effect of calcitonin gene-related peptide, neuropeptide Y, substance P, and vasoactive intestinal peptide on interleukin-1beta, interleukin-6 and tumor necrosis factor-alpha production by peripheral whole blood cells from rheumatoid arthritis and osteoarthritis patients. Regul Pept 115 (2003) 19-24
27. Karl T., Chwalisz W.T., Wedekind D., Hedrich H.J., Hoffmann T., Jacobs R., et al. Localization, transmission, spontaneous mutations, and variation of function of the Dpp4 (Dipeptidyl-peptidase IV; CD26) gene in rats. Regul Pept 115 (2003) 81-90
28. Kawamura N., Tamura H., Obana S., Wenner M., Ishikawa T., Nakata A., et al. Differential effects of neuropeptides on cytokine production by mouse helper T cell subsets. Neuroimmunomodulation 5 (1998) 9-15
29. Kubota T., Iizuka H., Bachovchin W.W., and Stollar B.D. Dipeptidyl peptidase IV (DP IV) activity in serum and on lymphocytes of MRL/Mp-lpr/lpr mice correlates with disease onset. Clin Exp Immunol 96 (1994) 292-296
30. Kuo L.E., Abe K., and Zukowska Z. Stress, NPY and vascular remodeling: implications for stress-related diseases. Peptides 28 (2007) 435-440
31. Laouar A., Wietzerbin J., and Bauvois B. Divergent regulation of cell surface protease expression in HL-60 cells differentiated into macrophages with granulocyte macrophage colony stimulating factor or neutrophils with retinoic acid. Int Immunol 5 (1993) 965-973
32. Lin Q., Zou X., Ren Y., Wang J., Fang L., and Willis W.D. Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin. Neuroscience 123 (2004) 337-347
33. Maeda K., Yasuda M., Kaneda H., Maeda S., and Yamadori A. Cerebrospinal fluid (CSF) neuropeptide Y- and somatostatin-like immunoreactivities in man. Neuropeptides 27 (1994) 323-332
34. Mapp P.I., Kidd B.L., Gibson S.J., Terry J.M., Revell P.A., Ibrahim N.B., et al. Substance P-, calcitonin gene-related peptide- and C-flanking peptide of neuropeptide Y-immunoreactive fibres are present in normal synovium but depleted in patients with rheumatoid arthritis. Neuroscience 37 (1990) 143-153
35. Matsuda H., Brumovsky P.R., Kopp J., Pedrazzini T., and Hokfelt T. Distribution of neuropeptide Y Y1 receptors in rodent peripheral tissues. J Comp Neurol 449 (2002) 390-404
36. Medina S., Del Rio M., Hernanz A., and De la Fuente M. Age-related changes in the neuropeptide Y effects on murine lymphoproliferation and interleukin-2 production. Peptides 21 (2000) 1403-1409
37. Mentlein R. Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides. Regul Pept 85 (1999) 9-24
38. Michel M.C., Beck-Sickinger A., Cox H., Doods H.N., Herzog H., Larhammar D., et al. XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol Rev 50 (1998) 143-150
39. Morimoto C., and Schlossman S.F. The structure and function of CD26 in the T-cell immune response. Immunol Rev 161 (1998) 55-70
40. Mousli M., Trifilieff A., Pelton J.T., Gies J.P., and Landry Y. Structural requirements for neuropeptide Y in mast cell and G protein activation. Eur J Pharmacol 289 (1995) 125-133
41. Mrazkova O., Grim M., and Carlson B.M. Enzymatic heterogeneity of the capillary bed of rat skeletal muscles. Am J Anat 177 (1986) 141-148
42. Nave H., Bedoui S., Moenter F., Steffens J., Felies M., Gebhardt T., et al. Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y2 receptor activation. J Neuroimmunol 155 (2004) 1-12
43. Naveilhan P., Hassani H., Lucas G., Blakeman K.H., Hao J.X., Xu X.J., et al. Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor. Nature 409 (2001) 513-517
44. Nilsson T., Lind H., Brunkvall J., and Edvinsson L. Vasodilation in human subcutaneous arteries induced by neuropeptide Y is mediated by neuropeptide Y Y1 receptors and is nitric oxide dependent. Can J Physiol Pharmacol 78 (2000) 251-255
45. Potter E.K., Mitchell L., McCloskey M.J., Tseng A., Goodman A.E., Shine J., et al. Pre- and postjunctional actions of neuropeptide Y and related peptides. Regul Pept 25 (1989) 167-177
46. Prod'homme T., Weber M.S., Steinman L., and Zamvil S.S. A neuropeptide in immune-mediated inflammation, Y?. Trends Immunol 27 (2006) 164-167
47. Reinhold D., Bank U., Buhling F., Kahne T., Kunt D., Faust J., et al. Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) specifically suppress proliferation and modulate cytokine production of strongly CD26 expressing U937 cells. Immunobiology 192 (1994) 121-136
48. Reinhold D., Wrenger S., Bank U., Buhling F., Hoffmann T., Neubert K., et al. CD26 mediates the action of HIV-1 Tat protein on DNA synthesis and cytokine production in U937 cells. Immunobiology 195 (1996) 119-128
49. Silva A.P., Cavadas C., Baisse-Agushi B., Spertini O., Brunner H.R., and Grouzmann E. NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-alpha and IFN-gamma in HUVEC. Regul Pept 116 (2003) 71-79
50. Sodhi A., Tarang S., and Kesherwani V. Concanavalin A induced expression of Toll-like receptors in murine peritoneal macrophages in vitro. Int Immunopharmacol 7 (2007) 454-463
51. Stanojevic S., Vujic V., Kovacevic-Jovanovic V., Mitic K., Kosec D., Horsten S., et al. Age-related effect of peptide YY (PYY) on paw edema in the rat: the function of Y1 receptors on inflammatory cells. Exp Gerontol 41 (2006) 793-799
52. Tsurumi K., Kyuki K., Niwa M., Kokuba S., and Fujimura H. Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 1st communication: inhibitory effects of rat paw edema. Arzneimittelforschung 36 (1986) 1796-1800
53. Wheway J., Herzog H., and Mackay F. NPY and receptors in immune and inflammatory diseases. Curr Top Med Chem 7 (2007) 1743-1752
54. Wheway J., Mackay C.R., Newton R.A., Sainsbury A., Boey D., Herzog H., et al. A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. J Exp Med 202 (2005) 1527-1538
55. Zukowska-Grojec Z. Neuropeptide Y: an adrenergic cotransmitter, vasoconstrictor, and a nerve-derived vascular growth factor. Adv Pharmacol 42 (1998) 125-128