Moderate exercise training decreases aortic superoxide production in myocardial infarcted rats

European Journal of Applied Physiology

Volumn 104, Issue 6, 2008, Pages 1045-1052

  Zanchi, Nelo Eidy ^a   Bechara, Luiz Roberto Grassmann ^a   Tanaka, Leonardo Yuji ^a   Debbas, Victor ^a   Bartholomeu, Teresa ^a   Ramires, Paulo Rizzo ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

NAD(P)H oxidase; Reactive oxygen species; Superoxide dismutase

Indexed keywords

NORADRENALIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

AEROBIC EXERCISE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; EXERCISE INTENSITY; EXERCISE TEST; HEART INFARCTION; MALE; NONHUMAN; PHYSICAL CAPACITY; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; TREATMENT RESPONSE; VASOCONSTRICTION; VASOMOTOR REFLEX;

EID: 56049114861     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-008-0861-0     Document Type: Article

References (37)

1. Adams V, Linke A, Kränkel N, Erbs S, Gielen S, Möbius-Winkler S et al (2005) Impact of regular physical activity on the NAD(P)H oxidase and angiotensin receptor system in patients with coronary artery disease. Circulation 111:555-562. doi: 10.1161/01.CIR.0000154560.88933.7E
2. Bauersachs J, Bouloumié A, Fraccarollo D, Hu K, Busse R, Ertl G (1999) Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: Role of enhanced vascular superoxide production. Circulation 100:292-298
3. Bauersachs J, Fleming I, Fraccarollo D, Busse R, Ertl G (2001) Prevention of endothelial dysfunction in heart failure by vitamin E: attenuation of vascular superoxide anion formation and increase in soluble guanylyl cyclase expression. Cardiovasc Res 51:344-350. doi: 10.1016/S0008-6363(01)00319-4
4. Bossaller C, Habib GB, Yamamoto H, Williams C, Wells S, Henry PD (1997) Impaired muscarinic endothelium-dependent relaxation and cyclic guanosine 5- monophosphate formation in atherosclerotic human coronary artery and rabbit aorta. J Clin Invest 79:170-174. doi: 10.1172/JCI112779
5. Brandes RP, Walles T, Koddenberg G, Gwinner W, Mügge A (1998) Endothelium-dependent vasodilatation in sprague-dawley rats with postinfarction hypertrophy: Lack of endothelial dysfunction in vitro. Basic Res Cardiol 93:463-469. doi: 10.1007/s003950050116
6. Darley-Usmar V, Wiseman H, Halliwell B (1995) Nitric oxide and oxygen radicals: A question of balance. FEBS Lett 369:131-135. doi: 10.1016/ 0014-5793(95)00764-Z
7. Delp MD, Laughlin MH (1997) Time course of enhanced endothelium-mediated dilation in aorta of trained rats. Med Sci Sports Exerc 29:1454-1461. doi: 10.1097/00005768-199711000-00011
8. Fukai T, Siegfried MR, Ushio-Fukai M, Cheng Y, Kojda G, Harrison DG (2000) Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest 105:1631-1639. doi: 10.1172/JCI9551
9. Furchgott RF, Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcoline. Nature 288:373-376. doi: 10.1038/288373a0
10. Gava NS, Véras-Silva AS, Negrão CE, Krieger EM (1995) Low-intensity exercise training attenuates cardiac b-adrenergic tone during exercise in spontaneously hypertensive rats. Hypertension 26:1129-1133
11. Graham DA, Rush JW (2004) Exercise training improves aortic endothelium-dependent vasorelaxation and determinants of nitric oxide bioavailability in spontaneously hypertensive rats. J Appl Physiol 96:2088-2096. doi: 10.1152/japplphysiol.01252.2003
12. Hambrecht R, Adams V, Erbs S, Linke A, Kränkel N, Shu Y et al (2003) Regular physical activity improves endothelial function in patients with coronary artery disease by increasing phosphorylation of endothelial nitric oxide synthase. Circulation 107:3152-3158. doi: 10.1161/01.CIR.0000074229.93804.5C
13. Higashi Y, Sasaki S, Kurisu S, Yoshimizu A, Sasaki N, Matsuura H et al (1999) Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: Role of endothelium-derived nitric oxide. Circulation 100:1194-1202
14. Indik JH, Goldman S, Gaballa MA (2001) Oxidative stress contributes to vascular endothelial dysfunction in heart failure. Am J Physiol 281:H1767-H1770
15. Indolfi C, Torella D, Coppola C, Curcio A, Rodriguez F, Bilancio A et al (2002) Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats. Circ Res 91:1190-1197. doi: 10.1161/01.RES.0000046233.94299.D6
16. Janiszewski M, Souza HP, Liu X, Pedro MA, Zweier JL, Laurindo FR (2002) Overestimation of NADH-driven vascular oxidase activity due to lucigenin artifacts. Free Radic Biol Med 32:446-453. doi: 10.1016/ S0891-5849(01)00828-0
17. Ji LL (2008) Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling. Free Radic Biol Med 44:142-152. doi: 10.1016/j.freeradbiomed.2007.02.031
18. Katusic ZS, Vanhoutte PM (1989) Superoxide anion is an endothelium derived contracting factor. Am J Physiol 257:H33-H37
19. Kojda G, Hambrecht R (2005) Molecular mechanisms of vascular adaptations to exercise. Physical activity as an effective antioxidant therapy? Cardiovasc Res 76:187-197. doi: 10.1016/j.cardiores.2005.04.032
20. Kojda G, Harrison D (1999) Interactions between NO and reactive oxygen species: Pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure. Cardiovasc Res 43:562-571. doi: 10.1016/ S0008-6363(99)00169-8
21. Kubo SH, Rector TS, Bank AJ, Williams RE, Heifetz SM (1991) Endothelium-dependent vasodilation is attenuated in patients with heart failure. Circulation 84:1589-1596
22. Laurindo FR, Pedro Mde A, Barbeiro HV, Pileggi F, Carvalho MH, Augusto O et al (1994) Vascular free radical release. Ex vivo and in vivo evidence for a flow-dependent endothelial mechanism. Circ Res 74:700-709
23. Leeuwenburgh C, Fiebig R, Chandwaney R, Ji LL (1994) Aging and exercise training in skeletal muscle: Responses of glutathione and antioxidant enzyme systems. Am J Physiol 267:R439-R445
24. Leite PF, Danilovic A, Moriel P, Dantas K, Marklund S, Dantas AP et al (2003) Sustained decrease in superoxide dismutase activity underlies constrictive remodeling after balloon injury in rabbits. Arterioscler Thromb Vasc Biol 23:2197-2202. doi: 10.1161/01.ATV.0000093980.46838.41
25. Munzel T, Harrison DG (1999) Increased superoxide in heart failure. A biochemical baroreflex gone awry. Circulation 100:216-218
26. Ohashi Y, Kawashima S, Hirata K, Yamashita T, Ishida T, Inoue N et al (1998) Hypotension and reduced nitric oxide-elicited vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. J Clin Invest 102:2061-2071. doi: 10.1172/JCI4394
27. Pereira RB, Sartório CL, Vassallo DV, Stefanon I (2005) Differences in tail vascular bed reactivity in rats with and without heart failure following myocardial infarction. J Pharmacol Exp Ther 312:1321-1325. doi: 10.1124/jpet.104.077701
28. Pfeffer MA, Pfeffer JM, Fishbein MC, Fletcher PJ, Spadaro J, Kloner RA et al (1979) Myocardial infarct size and ventricular function in rats. Circ Res 44:503-512
29. Pohl U, Busse R (1987) Endothelium-derived relaxant factor inhibits effects of nitrocompounds in isolated arteries. Am J Physiol 252:H307-H313
30. Powers SK, Ji LL, Leeuwenburgh C (1999) Exercise training induced alterations in skeletal muscle antioxidant capacity: A brief review. Med Sci Sports Exerc 31:987-997. doi: 10.1097/00005768-199907000-00011
31. Ramires PR, Ji LL (2001) Glutathione supplementation and training increases myocardial resistance to ischemia-reperfusion in vivo. Am J Physiol 281:679-688
32. Rush JW, Laughlin MH, Woodman CR, Price EM (2000) SOD-1 expression in pig coronary arterioles is increased by exercise training. Am J Physiol 279:H2068-H2076
33. Rush JW, Turk JR, Laughlin MH (2003) Exercise training regulates SOD-1 and oxidative stress in porcine aortic endothelium. Am J Physiol 284:H1378-H1387
34. Shepherd D, Garland PB (1969) The kinetic properties of citrate synthase from rat liver mitochondria. Biochem J 114:597-610
35. Teerlink JR, Gray GA, Clozel M, Clozel JP (1994) Increased vascular responsiveness to norepinephrine in rats with heart failure is endothelium dependent. Circulation 89:393-401
36. Thuillez C, Mulder P, Elfertak L, Blaysat G, Compagnon P, Henry JP et al (1995) Prevention of endothelial dysfunction in small and large arteries in a model of chronic heart failure. Effect of angiotensin converting enzyme inhibition. Am J Hypertens 8:7S-12S. doi: 10.1016/ 0895-7061(95)00027-M
37. Yamashita T, Kawashima S, Ohashi Y, Ozaki M, Rikitake Y, Inoue N, Hirata K, Akita H, Yokoyama M (2000) Mechanisms of reduced nitric oxide/ cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. Hypertension 36:97-102