Effect of Hydrochlorothiazide on Urinary Calcium Excretion in Dent Disease: An Uncontrolled Trial

American Journal of Kidney Diseases

Volumn 52, Issue 6, 2008, Pages 1084-1095

  Blanchard, Anne ^a,b,c   Vargas Poussou, Rosa ^a,b,d,e   Peyrard, Severine ^b,c   Mogenet, Agnes ^c,f   Baudouin, Veronique ^a,g,h   Boudailliez, Bernard ^i,j   Charbit, Marina ^a,f,g   Deschesnes, George ^a,g,h   Ezzhair, Nadia ^h   Loirat, Chantal ^a,g,h   Macher, Marie Alice ^a,g,h   Niaudet, Patrick ^a,f   Azizi, Michel ^a,b,c  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^c HÔpital Européen Georges Pompidou   (France)

^d HÔpital Necker Enfants Malades   (France)

^e INSERM   (France)

^f HÔPITAL NECKER ENFANTS MALADES   (France)

^g Service de Néphrologie   (France)

^h HÔPITAL ROBERT DEBRÉ   (France)

ⁱ UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^j AMIENS UNIVERSITY HOSPITAL   (France)

more..

Author keywords

clinical trial; Dent disease; nephrolithiasis; thiazides

Indexed keywords

ALDOSTERONE; AMILORIDE; HYDROCHLOROTHIAZIDE; PLASMA PROTEIN; RENIN;

ADOLESCENT; ARTICLE; BLOOD SAMPLING; CALCIUM EXCRETION; CLINICAL ARTICLE; CLINICAL TRIAL; DEHYDRATION; DENT DISEASE; DRUG DOSE TITRATION; DRUG MEGADOSE; DRUG TOLERABILITY; DRUG WITHDRAWAL; HUMAN; HYPERCALCIURIA; HYPOKALEMIA; HYPONATREMIA; HYPOVOLEMIA; KIDNEY FAILURE; LOW DRUG DOSE; MALE; MUSCLE CRAMP; NUCLEOTIDE SEQUENCE; OPEN STUDY; PHENOTYPE; RISK BENEFIT ANALYSIS; SCHOOL CHILD; SIDE EFFECT; TREATMENT DURATION; TREATMENT OUTCOME; URINALYSIS; URINARY EXCRETION; WEAKNESS; WEIGHT REDUCTION; X CHROMOSOME LINKED DISORDER;

ADOLESCENT; CALCIUM; CHILD; DIURETICS; HUMANS; HYDROCHLOROTHIAZIDE; HYPERCALCIURIA; HYPOPHOSPHATEMIA; MALE; PROTEINURIA; RENAL AMINOACIDURIAS; SYNDROME;

EID: 56049105375     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2008.08.021     Document Type: Article

References (35)

1. Igarashi T., Gunther W., Sekine T., et al. Functional characterization of renal chloride channel, CLCN5, mutations associated with Dent's Japan disease. Kidney Int 54 (1998) 1850-1856
2. Bolino A., Devoto M., Enia G., Zoccali C., Weissenbach J., and Romeo G. Genetic mapping in the Xp11.2 region of a new form of X-linked hypophosphatemic rickets. Eur J Hum Genet 1 (1993) 269-279
3. Frymoyer P.A., Scheinman S.J., Dunham P.B., Jones D.B., Hueber P., and Schroeder E.T. X-Linked recessive nephrolithiasis with renal failure. N Engl J Med 325 (1991) 681-686
4. Wrong O.M., Norden A.G., and Feest T.G. Dent's disease; A familial proximal renal tubular syndrome with low-molecular-weight proteinuria, hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance. QJM 87 (1994) 473-493
5. Cho H.Y., Lee B.H., Choi H.J., Ha I.S., Choi Y., and Cheong H.I. Renal manifestations of Dent disease and Lowe syndrome. Pediatr Nephrol 23 (2008) 243-249
6. Hoopes Jr. R.R., Shrimpton A.E., Knohl S.J., et al. Dent disease with mutations in OCRL1. Am J Hum Genet 76 (2005) 260-267
7. Sekine T., Nozu K., Iyengar R., et al. OCRL1 mutations in patients with Dent disease phenotype in Japan. Pediatr Nephrol 22 (2007) 975-980
8. Utsch B., Bokenkamp A., Benz M.R., et al. Novel OCRL1 mutations in patients with the phenotype of Dent disease. Am J Kidney Dis 48 (2006) 942 e1-e14
9. +-ATPase without ultrastructural changes in kidneys of Dent's disease patients. Kidney Int 63 (2003) 1285-1295
10. Piwon N., Gunther W., Schwake M., Bosl M.R., and Jentsch T.J. ClC-5 Cl-channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature 408 (2000) 369-373
11. Souza-Menezes J., Morales M.M., Tukaye D.N., Guggino S.E., and Guggino W.B. Absence of ClC5 in knockout mice leads to glycosuria, impaired renal glucose handling and low proximal tubule GLUT2 protein expression. Cell Physiol Biochem 20 (2007) 455-464
12. Ludwig M., Utsch B., Balluch B., Frund S., Kuwertz-Broking E., and Bokenkamp A. Hypercalciuria in patients with CLCN5 mutations. Pediatr Nephrol 21 (2006) 1241-1250
13. Cebotaru V., Kaul S., Devuyst O., et al. High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease. Kidney Int 68 (2005) 642-652
14. Silva I.V., Cebotaru V., Wang H., et al. The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover. J Bone Miner Res 18 (2003) 615-623
15. Sayer J.A., Carr G., and Simmons N.L. Nephrocalcinosis: Molecular insights into calcium precipitation within the kidney. Clin Sci (Lond) 106 (2004) 549-561
16. Sayer J.A., Carr G., and Simmons N.L. Calcium phosphate and calcium oxalate crystal handling is dependent upon CLC-5 expression in mouse collecting duct cells. Biochim Biophys Acta 1689 (2004) 83-90
17. Scheinman S.J. X-Linked hypercalciuric nephrolithiasis: Clinical syndromes and chloride channel mutations. Kidney Int 53 (1998) 3-17
18. Raja K.A., Schurman S., D'Mello R.G., et al. Responsiveness of hypercalciuria to thiazide in Dent's disease. J Am Soc Nephrol 13 (2002) 2938-2944
19. Sinaiko A.R. Hypertension in children. N Engl J Med 335 (1996) 1968-1973
20. Carlsen J.E., Kober L., Torp-Pedersen C., and Johansen P. Relation between dose of bendrofluazide, antihypertensive effect, and adverse biochemical effects. BMJ 300 (1990) 975-978
21. Harper R., Ennis C.N., Sheridan B., Atkinson A.B., Johnston G.D., and Bell P.M. Effects of low dose versus conventional dose thiazide diuretic on insulin action in essential hypertension. BMJ 309 (1994) 226-230
22. Hollander W., and Wilkins R.W. Chlorothiazide: A new type of drug for the treatment of arterial hypertension. BMQ 8 (1957) 69-75
23. Sorof J.M., Cargo P., Graepel J., et al. Beta-blocker/thiazide combination for treatment of hypertensive children: A randomized double-blind, placebo-controlled trial. Pediatr Nephrol 17 (2002) 345-350
24. Norden A.G., Scheinman S.J., Deschodt-Lanckman M.M., et al. Tubular proteinuria defined by a study of Dent's (CLCN5 mutation) and other tubular diseases. Kidney Int 57 (2000) 240-249
25. Lloyd S.E., Pearce S.H., Gunther W., et al. Idiopathic low molecular weight proteinuria associated with hypercalciuric nephrocalcinosis in Japanese children is due to mutations of the renal chloride channel (CLCN5). J Clin Invest 99 (1997) 967-974
26. Blanchard A., Jeunemaitre X., Coudol P., et al. Paracellin-1 is critical for magnesium and calcium reabsorption in the human thick ascending limb of Henle. Kidney Int 59 (2001) 2206-2215
27. Bolland M.J., Ames R.W., Horne A.M., Orr-Walker B.J., Gamble G.D., and Reid I.R. The effect of treatment with a thiazide diuretic for 4 years on bone density in normal postmenopausal women. Osteoporos Int 18 (2007) 479-486
28. Beermann B., and Groschinsky-Grind M. Pharmacokinetics of hydrochlorothiazide in man. Eur J Clin Pharmacol 12 (1977) 297-303
29. Berglund G., Andersson O., Larsson O., and Wilhelmsen L. Antihypertensive effect and side-effects of bendroflumethiazide and propranolol. Acta Med Scand 199 (1976) 499-506
30. 2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. J Clin Invest 115 (2005) 1651-1658
31. Eladari D., Leviel F., Pezy F., Paillard M., and Chambrey R. Rat proximal NHE3 adapts to chronic acid-base disorders but not to chronic changes in dietary NaCl intake. Am J Physiol Renal Physiol 282 (2002) F835-F843
32. Seikaly M.G., and Baum M. Thiazide diuretics arrest the progression of nephrocalcinosis in children with X-linked hypophosphatemia. Pediatrics 108 (2001) E6
33. Cox J.P., Yamamoto K., Christie P.T., et al. Renal chloride channel, CLCN5, mutations in Dent's disease. J Bone Miner Res 14 (1999) 1536-1542
34. Cheong H.I., Lee J.W., Zheng S.H., et al. Phenotype and genotype of Dent's disease in three Korean boys. Pediatr Nephrol 20 (2005) 455-459
35. Takemura T., Hino S., Ikeda M., et al. Identification of two novel mutations in the CLCN5 gene in Japanese patients with familial idiopathic low molecular weight proteinuria (Japanese Dent's disease). Am J Kidney Dis 37 (2001) 138-143