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Volumn 27, Issue 7, 2008, Pages 553-558

Electrophysiological safety of sibutramine HCl

Author keywords

Action potential; hERG channel; L type Ca channel; Na channel; Sibutramine HCl

Indexed keywords

CALCIUM CHANNEL L TYPE; POTASSIUM CHANNEL HERG; SIBUTRAMINE; SODIUM CHANNEL; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; ANOREXIGENIC AGENT; CYCLOBUTANE DERIVATIVE;

EID: 56049102367     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/0960327108095991     Document Type: Article
Times cited : (4)

References (7)
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    • Nisoli, E.1    Carruba, M.O.2
  • 2
    • 18044391464 scopus 로고    scopus 로고
    • Safety pharmacology of sibutramine mesylate, an anti-obesity drug
    • Kim EJ Park EK Suh KH. Safety pharmacology of sibutramine mesylate, an anti-obesity drug. Hum Exp Toxicol 2005 ; 24: 109 - 119.
    • (2005) Hum Exp Toxicol , vol.24 , pp. 109-119
    • Kim, E.J.1    Park, E.K.2    Suh, K.H.3
  • 3
    • 0032852016 scopus 로고    scopus 로고
    • Sibutramine: A serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity
    • Luque CA Rey JA. Sibutramine: a serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity. Ann Pharmacother 1999 ; 33: 968 - 978.
    • (1999) Ann Pharmacother , vol.33 , pp. 968-978
    • Luque, C.A.1    Rey, J.A.2
  • 4
    • 0036733520 scopus 로고    scopus 로고
    • Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction
    • Zannad F Gille B Grentzinger A Bruntz JF Hammadi M Boivin JM. Effects of sibutramine on ventricular dimensions and heart valves in obese patients during weight reduction. Am Heart J 2002 ; 144: 508 - 515.
    • (2002) Am Heart J , vol.144 , pp. 508-515
    • Zannad, F.1    Gille, B.2    Grentzinger, A.3    Bruntz, J.F.4    Hammadi, M.5    Boivin, J.M.6
  • 5
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    • The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid noradrenergic down-regulation
    • Buckett WR Thomas PC Luscombe GP. The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid noradrenergic down-regulation. Prog Neuropsychopharmacol Biol Psychiatry 1988 ; 12: 575 - 584.
    • (1988) Prog Neuropsychopharmacol Biol Psychiatry , vol.12 , pp. 575-584
    • Buckett, W.R.1    Thomas, P.C.2    Luscombe, G.P.3
  • 6
    • 27444443769 scopus 로고    scopus 로고
    • A pilot study to evaluate the pharmacokinetics of sibutramine in healthy subjects under fasting and fed conditions
    • Abolfathi Z Couture J Vallee F LeBel M Tanguay M Masson E. A pilot study to evaluate the pharmacokinetics of sibutramine in healthy subjects under fasting and fed conditions. J Pharm Pharm Sci 2004 ; 127: 345 - 349.
    • (2004) J Pharm Pharm Sci , vol.127 , pp. 345-349
    • Abolfathi, Z.1    Couture, J.2    Vallee, F.3    Lebel, M.4    Tanguay, M.5    Masson, E.6
  • 7
    • 0344492207 scopus 로고    scopus 로고
    • Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: Evidence for a provisional safety margin in drug development
    • Redfern WS Carlsson L Davis AS Lynch WG MacKenzie I Palethorpe S. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc Res 2003 ; 58: 32 - 45.
    • (2003) Cardiovasc Res , vol.58 , pp. 32-45
    • Redfern, W.S.1    Carlsson, L.2    Davis, A.S.3    Lynch, W.G.4    MacKenzie, I.5    Palethorpe, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.