Energy restriction impairs natural killer cell function and increases the severity of influenza infection in young adult male C57BL/6 mice

Journal of Nutrition

Volumn 138, Issue 11, 2008, Pages 2269-2275

  Ritz, Barry W ^a   Aktan, Idil ^a   Nogusa, Shoko ^a   Gardner, Elizabeth M ^a,b  

^a DREXEL UNIVERSITY   (United States)

^b Michigan State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; C57BL 6 MOUSE; CALORIC RESTRICTION; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DISEASE SEVERITY; FEEDING BEHAVIOR; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS A H1N1; INNATE IMMUNITY; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PROTEIN EXPRESSION; WEIGHT REDUCTION;

ANIMALS; ANOREXIA; CELL LINE; DIET; DOGS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; INFLUENZA A VIRUS, H1N1 SUBTYPE; INTERFERON-ALPHA; INTERFERON-BETA; KILLER CELLS, NATURAL; LUNG; MALE; MICE; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE INFECTIONS; WEIGHT LOSS;

INFLUENZA A VIRUS; MUS;

EID: 55949137713     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.108.093633     Document Type: Article

References (32)

1. Speakman JR, Hambly C. Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan. J Nutr. 2007;137:1078-86.
2. Masoro EJ. Overview of caloric restriction and ageing. Mech Ageing Dev. 2005;126:913-22.
3. Yamaza H, Chiba T, Higami Y, Shimokawa I. Lifespan extension by caloric restriction: an aspect of energy metabolism. Microsc Res Tech. 2002;59:325-30.
4. Wanagat J, Allison DB, Weindruch R. Caloric intake and aging: mechanisms in rodents and a study in nonhuman primates. Toxicol Sci. 1999;52S:35-40.
5. McCay CM, Cromwell MF, Maynard LA. The effect of retarded growth upon the length of the lifespan and ultimate body size. J Nutr. 1935;10:63-79.
6. Barger JL, Walford RL, Weindruch R. The retardation of aging by caloric restriction: its significance in the transgenic era. Exp Gerontol. 2003;38:1343-51.
7. Effros RB, Walford RL, Weindruch R, Mitcheltree C. Influences of dietary restriction on immunity to influenza in aged mice. J Gerontol. 1991;46:B142-7.
8. Weindruch R, Walford RL, Fligiel S, Guthrie D. The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr. 1986;116:641-54.
9. Weindruch R. Dietary restriction, tumors, and aging in rodents. J Gerontol. 1989;44:67-71.
10. Ritz BW, Gardner EM. Malnutrition and energy restriction differentially affect viral immunity. J Nutr. 2006;136:1141-4.
11. Messaoudi I,Warner J, Fischer M, Park B, Hill B, Mattison J, Lane MA, Roth GS, Ingram DK, et al. Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates. Proc Natl Acad Sci USA. 2006;103:19448-53.
12. Nikolich-Zugich J, Messaoudi I. Mice and flies and monkeys too: caloric restriction rejuvenates the aging immune system of non-human primates. Exp Gerontol. 2005;40:884-93.
13. Pahlavani MA. Caloric restriction and immunosenescence: a current perspective. Front Biosci. 2000;5:D580-7.
14. Weindruch R, Gottesman SRS, Walford RL. Modification of age-related immune decline in mice dietarily restricted from or after midadulthood. Proc Natl Acad Sci USA. 1982;79:898-902.
15. Venkatraman J, Fernandes G. Modulation of age-related alterations in membrane composition and receptor-associated immune functions by food restriction in Fischer 344 rats. Mech Ageing Dev. 1992;63:27-44.
16. Weindruch R, Devens BH, Raff HV, Walford RL. Influence of dietary restriction and aging on natural killer cell activity in mice. J Immunol. 1983;130:993-6.
17. Gardner EM. Caloric restriction decreases survival of aged mice in response to primary influenza infection. J Gerontol A Biol Sci Med Sci. 2005;60:688-94.
18. Turturro A, WittWW, Lewis S, Hass BS, Lipman RD, Hart RW. Growth curves and survival characteristics of the animals used in the biomarkers of aging program. J Gerontol A Biol Sci Med Sci. 1999;54:B492-501.
19. Ritz BW, Nogusa S, Ackerman EA, Gardner EM. Supplementation with active hexose correlated compound increases the innate immune response of young mice to primary influenza infection. J Nutr. 2006;136:2868-73.
20. Plett PA, Gardner EM, Murasko DM. Age-related changes in interferon α/β receptor expression, binding, and induction of apoptosis in natural killer cells from C57BL/6 mice. Mech Ageing Dev. 2000;118:129-44.
21. Hunzeker J, Padgett DA, Sheridan PA, Dhabhar FS, Sheridan JF. Modulation of natural killer cell cytotoxicity by restraint stress during an influenza A/PR8 infection in mice. Brain Behav Immun. 2004;18:526-35.
22. Smith AG, Sheridan PA, Harp JB, Beck MA. Diet-induced obese mice have increased mortality and altered immune responses when infected with influenza virus. J Nutr. 2007;137:1236-43.
23. Nelson HK, Shi Q, Van Dael P, Schiffrin EJ, Blum S, Barclay D, Levander OA, Beck MA. Host nutritional selenium status as a driving force for influenza virus mutations. FASEB J. 2001;15:1846-8.
24. Bender BS, Taylor SF, Zander DS, Cottey R. Pulmonary immune response of young and aged mice after influenza challenge. J Lab Clin Med. 1995;126:169-77.
25. Garcia-Sastre A, Biron CA. Type 1 interferons and the virus-host defense: a lesson in détente. Science. 2006;312:879-82.
26. Nguyen KB, Salazar-Mather TP, Dalod MY, Van Deusen JB, Wei XQ, Liew FY, Caligiuri MA, Durbin JE, Biron CA. Coordinated and distinct roles for IFNalpha/beta, IL-12, and IL-15 regulation of NK cell response to viral infection. J Immunol. 2002;169:4279-87.
27. Liang S, Wei H, Sun R, Tian Z. IFNα regulates NK cell cytotoxicity through STAT1 pathway. Cytokine. 2003;23:190-9.
28. Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol. 2003;3:133-46.
29. Cousens LP, Orange JS, Su HC, Biron CA. Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection. Proc Natl Acad Sci USA. 1997;94:634-9.
30. Niiya T, Akbar SM, Yoshida O, Miyake T, Matsuura B, Murakami H, Abe M, Hiasa Y, Onji M. Impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice. J Nutr. 2007;137:671-5.
31. Kassim SH, Rajasagi NK, Zhao X, Chervenak R, Jennings SR. In vivo ablation of CD11c-positive dendritic cells increases susceptibility of herpes simplex virus type 1 infection and dimishes NK and T-cell responses. J Virol. 2006;80:3985-93.
32. Ballas ZK, Rasmussen W. Lymphokine-activated killer (LAK) cells. IV. Characterization of murine LAK effector subpopulations. J Immunol. 1990;144:386-95.