Correlation between β-catenin widespread nuclear expression and matrix metalloproteinase-7 overexpression in sporadic desmoid tumors

Human Pathology

Volumn 39, Issue 12, 2008, Pages 1802-1808

  Matono, Hiroshi ^a   Oda, Yoshinao ^a   Nakamori, Mari ^a   Tamiya, Sadafumi ^a   Yamamoto, Hidetaka ^a   Yokoyama, Ryohei ^b   Saito, Tsuyoshi ^a   Iwamoto, Yukihide ^a   Tsuneyoshi, Masazumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NATIONAL KYUSHU CANCER CENTER   (Japan)

Author keywords

catenin; Desmoid tumors; Matrix metalloproteinase 7; Wnt signaling

Indexed keywords

BETA CATENIN; MATRILYSIN; MESSENGER RNA;

ADULT; AGED; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DESMOID TUMOR; FEMALE; FROZEN SECTION; GENE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MATRIX METALLOPROTEINASE 7 GENE; MISSENSE MUTATION; POINT MUTATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ADOLESCENT; ADULT; AGED; BETA CATENIN; CELL NUCLEUS; CHILD; CHILD, PRESCHOOL; FEMALE; FIBROMATOSIS, AGGRESSIVE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INFANT; MALE; MATRIX METALLOPROTEINASE 7; MIDDLE AGED; MUTATION, MISSENSE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SOFT TISSUE NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 55949136838     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2008.05.005     Document Type: Article

References (28)

1. Merchant N.B., Lewis J.J., Woodruff J.M., et al. Extremity and trunk desmoid tumors: a multifactorial analysis of outcome. Cancer 86 (1999) 2045-2052
2. Tejpar S., Nollet F., Li C., et al. Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). Oncogene 18 (1999) 6615-6620
3. Bhattacharya B., Dilworth H.P., Iacobuzio-Donahue C., et al. Nuclear β-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions. Am J Surg Pathol 29 (2005) 653-659
4. Ng T.L., Gown A.M., Barry T.S., et al. Nuclear beta-catenin in mesenchymal tumors. Mod Pathol 18 (2005) 68-74
5. Amary M.F.C., Pauwels P., Meulemans E., et al. Detection of β-catenin mutations in paraffin-embedded sporadic desmoid-type fibromatosis by mutaion-specific restriction enzyme digestion (MSRED): an ancillary diagnostic tool. Am J Surg Pathol 31 (2007) 1299-1309
6. Carlson J.W., and Fletcher C.D.M. Immunohistochemistry for β-catenin in the differential diagnosis of spindle cell lesions: analysis of a series and review of the literature. Histopathology 51 (2007) 509-514
7. Jilong Y., Jian W., Xiaoyan Z., et al. Analysis of APC/beta-catenin genes mutations and Wnt signalling pathway in desmoid-type fibromatosis. Pathology 39 (2007) 319-325
8. Kotiligam D., Lazar A.J., Pollock R.E., et al. Desmoid tumor: a disease opportune for molecular insights. Histol Histopathol 23 (2008) 117-126
9. He T.C., Sparks A.B., Rago C., et al. Identification of c-MYC as a target of the APC pathway. Science 281 (1998) 1509-1512
10. Tetsu O., and McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398 (1999) 422-426
11. Brabletz T., Jung A., Dag S., et al. β-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol 155 (1999) 1033-1038
12. Crawford H.C., Fingleton B.M., Rudolph-Owen L.A., et al. The metalloproteinase matrilysin is a target gene of β-catenin transactivation in intestinal tumors. Oncogene 18 (1999) 2883-2891
13. Deryugina E.I., and Quigley J.P. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25 (2006) 9-34
14. Denys H., Wever O.D., Nusgens B., et al. Invasion and MMP expression profile in desmoid tumours. Br J Cancer 90 (2004) 1443-1449
15. Ii M., Yamamoto H., Adachi Y., et al. Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Exp Biol Med 231 (2007) 20-27
16. Saito T., Oda Y., Tanaka K., et al. β-catenin nuclear expression correlates with cyclin D1 overexpression in sporadic desmoid tumours. J Pathol 195 (2001) 222-228
17. Saito T., Oda Y., Kawaguchi K., et al. Possible association between higher β-catenin mRNA expression and mutated β-catenin in sporadic desmoid tumors: real-time semiquantitative assay by TaqMan polymerase chain reaction. Lab Invest 82 (2002) 97-103
18. Goldblum J., and Fletcher J.A. Desmoid-type fibromatoses. In: Fletcher C.D.M., Unni K.K., and Mertens F. (Eds). World Health Organization classification of tumours. Pathology and genetics: tumours of soft tissue and bone (2002), International Agency for Research on Cancer (IARC), Lyon, France 83-84
19. Machin P., Catasus L., Pons C., et al. CTNNB1 mutations and β-catenin expression in endometrial carcinomas. Hum Pathol 33 (2002) 206-212
20. Iwao K., Nakamori S., Kameyama M., et al. Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res 58 (1998) 1021-1026
21. Ogasawara N., Tsukamoto T., Mizoshita T., et al. Mutations and nuclear accumulation of β-catenin correlate with intestinal phenotypic expression in human gastric cancer. Histopathology 49 (2006) 612-621
22. Ozaki S., Ikeda S., Ishizaki Y., et al. Alterations and correlations of the components in the Wnt signaling pathway and its target genes in breast cancer. Oncol Rep 14 (2005) 1437-1443
23. Chesire D.R., Ewing C.M., Sauvageot J., et al. Detection and analysis of beta-catenin mutations in prostate cancer. Prostate 45 (2000) 323-334
24. McDonnell S., Narve M., Coffey Jr. R.J., et al. Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog 4 (1991) 527-533
25. Jones L.E., Humphreys M.J., Cambell F., et al. Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival. Clin Cancer Res 10 (2004) 2832-2845
26. Martin M.D., and Matrisian L.M. The other side of MMPs: protective roles in tumor progression. Cancer Metastasis Rev 26 (2007) 717-724
27. Pozzi A., Moberg P.E., Miles L.A., et al. Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization. Proc Natl Acad Sci U S A 97 (2000) 2202-2207
28. Jodele S., Blavier L., Yoon J.M., et al. Modifying the soil to affect the seed: role of stromal-derived matrix metalloproteinases in cancer progression. Cancer Metastasis Rev. 25 (2006) 35-43