Knockouts of Se-glutathione peroxidase-1 and Cu,Zn superoxide dismutase exert different impacts on femoral mechanical performance of growing mice

Molecular Nutrition and Food Research

Volumn 52, Issue 11, 2008, Pages 1334-1339

  Wang, Xiaodan ^a   Gillen, Elizabeth A ^b   Van Der Meulen, Marjolein C H ^b,c   Xin, Gen Lei ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Cornell University   (United States)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Antioxidant enzyme; Biomechanics; Bone; Mouse; Nutrition

Indexed keywords

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; SUPEROXIDE DISMUTASE;

ANIMAL; ARTICLE; BIOMECHANICS; BODY WEIGHT; DRUG EFFECT; ENZYMOLOGY; FEMALE; FEMUR; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; MECHANICAL STRESS; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; TENSILE STRENGTH;

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ANIMALS; BIOMECHANICS; BODY WEIGHT; FEMALE; FEMUR; GENOTYPE; GLUTATHIONE PEROXIDASE; MICE; MICE, KNOCKOUT; STRESS, MECHANICAL; SUPEROXIDE DISMUTASE; TENSILE STRENGTH;

MURINAE; MUS; PICHIA JADINII;

EID: 55949127970     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200700351     Document Type: Article

References (46)

1. Key, L. L., Jr., Ries, W. L., Taylor, R. G., Hays, B. D., Pitzer, B. L., Oxygen derived free radicals in osteoclasts: The specificity and location of the nitroblue tetrazolium reaction, Bone 1990, 11, 115-119.
2. Steinbeck, M. J., Appel, W. H., Jr., Verhoeven, A. J., Karnovsky, M. J., NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone, J. Cell. Biol. 1994, 126, 765-772.
3. Franzoso, G., Carlson, L., Xing, L., Poljak, L., et al., Requirement for NF-kappaB in osteoclast and B-cell development, Genes Dev. 1997, 11, 3482-3496.
4. Schreck, R., Rieber, P., Baeuerle, P. A., Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1, EMBO J. 1991, 10, 2247-2258.
5. Mody, N., Parhami, F., Sarafian, T. A., Demer, L. L., Oxidative stress modulates osteoblastic differentiation of vascular and bone cells, Free Radic. Biol. Med. 2001, 31, 509-519.
6. Liu, H. C., Chen, R. M., Jian,W. C., Lin, Y. L., Cytotoxic and antioxidant effects of the water extract of the traditional Chinese herb gusuibu (Drynaria fortunei) on rat osteoblasts, J. Formos. Med. Assoc. 2001, 100, 383-388.
7. Basu, S., Michaelsson, K., Olofsson, H., Johansson, S., Melhus, H., Association between oxidative stress and bone mineral density, Biochem. Biophys. Res. Commun. 2001, 288, 275-279.
8. Sung, J. Y., Hong, J. H., Kang, H. S., Choi, I., et al., Methotrexate suppresses the interleukin-6 induced generation of reactive oxygen species in the synoviocytes of rheumatoid arthritis, Immunopharmacology 2000, 47, 35-44.
9. -•), superoxide dismutases, and related matters, J. Biol. Chem. 1997, 272, 18515-18517.
10. Rotruck, J. T., Pope, A. L., Ganther, H. E., Swanson, A. B., et al., Selenium: Biochemical role as a component of glutathione peroxidase, Science 1973, 179, 588-590.
11. Okado-Matsumoto, A., Fridovich, I., Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria, J. Biol. Chem. 2001, 276, 38388-38393.
12. Ries, W. L., Key, L. L., Jr., Rodriguiz, R. M., Nitroblue tetrazolium reduction and bone resorption by osteoclasts in vitro inhibited by a manganese-based superoxide dismutase mimic, J. Bone Miner. Res. 1992, 7, 931-939.
13. Wu, J., Xu, G. L., Plasma selenium content, platelet glutathione peroxidase and superoxide dismutase activity of residents in Kashin-Beck disease affected area in China, J. Trace Elem. Electrolytes Health Dis. 1987, 1, 39-43.
14. Zhang, J., Munger, R. G., West, N. A., Cutler, D. R., et al., Antioxidant intake and risk of osteoporotic hip fracture in Utah: An effect modified by smoking status, Am. J. Epidemiol. 2006, 163, 9-17.
15. Ren, F. L., Guo, X., Zhang, R. J.,Wang, S. h. J., et al., Effects of selenium and iodine deficiency on bone, cartilage growth plate and chondrocyte differentiation in two generations of rats, Osteoarthritis Cartilage 2007, 15, 1171-1177.
16. Turan, B., Can, B., Delilbasi, E., Selenium combined with vitamin E and vitamin C restores structural alterations of bones in heparin-induced osteoporosis, Clin. Rheumatol. 2003, 22, 432-436.
17. Esposito, L. A., Kokoszka, J. E.,Waymire, K. G., Cottrell, B., et al., Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene, Free Radic. Biol. Med. 2000, 28, 754-766.
18. Cheng, W. H., Ho, Y. S., Valentine, B. A., Ross, D. A., et al., Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice, J. Nutr. 1998, 128, 1070-1076.
19. Lean, J. M., Jagger, C. J., Kirstein, B., Fuller, K., Chambers, T. J., Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation, Endocrinology 2005, 146, 728-735.
20. Evans, D. M., Ralston, S. H., Nitric oxide and bone, J. Bone Miner. Res. 1996, 11, 300-305.
21. Arjmandi, B., Juma, S., Beharka, A., Bapna, M., et al., Vitamin E improves bone quality in the aged but not in young adult male mice, J. Nutr. Biochem. 2002, 13, 543-549.
22. Rao, L. G., Krishnadev, N., Banasikowska, K., Rao, A. V., Lycopene I-effect on osteoclasts: Lycopene inhibits basal and parathyroid hormone-stimulated osteoclast formation and mineral resorption mediated by reactive oxygen species in rat bone marrow cultures, J. Med. Food 2003, 6, 69-78.
23. Maggio, D., Barabani, M., Pierandrei, M., Polidori, M. C., et al., Marked decrease in plasma antioxidants in aged osteoporotic women: Results of a cross-sectional study, J. Clin. Endocrinol. Metab. 2003, 88, 1523-1527.
24. Hsu, C. S., Shen, W. W., Hsueh, Y. M., Yeh, S. L., Soy isoflavone supplementation in postmenopausal women: Effects on plasma lipids, antioxidant enzyme activities and bone density, J. Reprod. Med. 2001, 46, 221-226.
25. Fu, Y., Cheng, W. H., Ross, D. A., Lei, X. G., Cellular glutathione peroxidase protects mice against lethal oxidative stress induced by various doses of diquat, Proc. Soc. Exp. Biol. Med. 1999, 222, 164-169.
26. Dimai, H. P., Linkhart, T. A., Linkhart, S. G., Donahue, L. R., et al., Alkaline phosphatase levels and osteoprogenitor cell numbers suggest bone formation may contribute to peak bone density differences between two inbred strains of mice, Bone 1998, 22, 211-216.
27. Tuckermann, J. P., Pittois, K., Partridge, N. C., Merregaert, J., Angel, P., Collagenase-3 (MMP-13) and integral membrane protein 2a (Itm2a) are marker genes of chondrogenic/osteoblastic cells in bone formation: Sequential temporal, and spatial expression of Itm2a, alkaline phosphatase, MMP-13, and osteocalcin in the mouse, J. Bone Miner. Res. 2000, 15, 1257-1265.
28. Wittrant, Y., Theoleyre, S., Couillaud, S., Dunstan, C., et al., Relevance of an in vitro osteoclastogenesis system to study receptor activator of NF-kB ligand and osteoprotegerin biological activities, Exp. Cell Res. 2004, 293, 292-301.
29. Hughes, D. E., Wright, K. R., Uy, H. L., Sasaki, A., et al., Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo, J. Bone Miner. Res. 1995, 10, 1478-1487.
30. Ralston, S. H., Ho, L. P., Helfrich, M. H., Grabowski, P. S., et al., Nitric oxide: A cytokine-induced regulator of bone resorption, J. Bone Miner. Res. 1995, 10, 1040-1049.
31. van der Meulen, M. C., Jepsen, K. J., Mikic, B., Understanding bone strength: Size isn't everything, Bone 2001, 29, 101-104.
32. Cheng, W., Fu, Y. X., Porres, J. M., Ross, D. A., Lei, X. G., Selenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids, and protein, FASEB J. 1999, 13, 1467-7145.
33. Cheng, W. H., Ho, Y. S., Ross, D. A., Valentine, B. A., et al., Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidases in various tissues, J. Nutr. 1997, 127, 1445-1450.
34. Walter, K., Schutt, C., in: Bergmeyer, H. U. (Ed.), Methods of Enzymatic Analysis - Acid and Alkaline Phosphatase in Serum, Academic Press, New York, London 1974, pp. 856-860.
35. Lowry, O. H., Rosebrough, N. F., Farr, A. L., Randall, R. J., Protein measurement with the Folin phenol reagent, J. Biol. Chem. 1951, 193, 265-275.
36. Mikic, B., Battaglia, T. C., Taylor, E. A., Clark, R. T., The effect of growth/differentiation factor-5 deficiency on femoral composition and mechanical behavior in mice, Bone 2002, 30, 733-737.
37. Beamer, W. G., Shultz, K. L., Donahue, L. R., Churchill, G. A., et al., Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice, J. Bone Miner. Res. 2001, 16, 1195-1206.
38. Lean, J. M., Davies, J. T., Fuller, K., Jagger, C. J., et al., A crucial role for thiol antioxidants in estrogen-deficiency bone loss, J. Clin. Invest. 2003, 112, 915-923.
39. Finkel, T., Holbrook, N. J., Oxidants, oxidative stress and the biology of ageing, Nature 2000, 408, 239-247.
40. Collin-Osdoby, P., Li, L., Rothe, L., Anderson, F., et al., Inhibition of avian osteoclast bone resorption by monoclonal antibody 121F: A mechanism involving the osteoclast free radical system, J. Bone Miner. Res. 1998, 13, 67-78.
41. Paolicchi, A., Dominici, S., Pieri, L., Maellaro, E., Pompella, A., Glutathione catabolism as a signaling mechanism, Biochem. Pharmacol. 2002, 64, 1027-1035.
42. Key, L. L., Jr., Wolf, W. C., Gundberg, C. M., Ries, W. L., Superoxide and bone resorption, Bone 1994, 15, 431-436.
43. Chae, H. J., Kang, J. S., Han, J. I., Bang, B. G., et al., Production of hydrogen peroxide by serum and its involvement in cell proliferation in ROS 17/2.8 osteoblasts, Immunopharmacol. Immunotoxicol. 2000, 22, 317-337.
44. Garnero, P., Sornay-Rendu, E., Duboeuf, F., Delmas, P. D., Markers of bone turnover predict postmenopausal forearm bone loss over 4 years: The OFELY study, J. Bone Miner. Res. 1999, 14, 1614-1621.
45. Lei, X. G., Zhu, J. H., McClung, J. P., Aregullin, M., Roneker, C. A., Mice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicity, Biochem J. 2006, 399, 455-461.
46. Flood, D. G., Reaume, A. G., Gruner, J. A., Hoffman, E. K., et al., Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions, Am. J. Pathol. 1999, 155, 663-672.