Osmosensing and osmosignaling in the liver

Wiener Medizinische Wochenschrift

Volumn 158, Issue 19-20, 2008, Pages 549-552

  Häussinger, Dieter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Apoptosis; Choleresis; Insulin resistance; Integrins; NADPH oxidase; Proteolysis; Vell volume

Indexed keywords

GLYCOGEN; MITOGEN ACTIVATED PROTEIN KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

AUTOPHAGY; CELL SWELLING; CELL VOLUME; CONFERENCE PAPER; ENZYME INHIBITION; HUMAN; HYDRATION; INSULIN RESISTANCE; INTRAHEPATIC CHOLESTASIS; LIVER CELL; LIVER FUNCTION; LIVER INJURY; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

AMINO ACIDS; ANIMALS; APOPTOSIS; BILE; CELL SIZE; HEPATOCYTES; HORMONES; HUMANS; INSULIN RESISTANCE; INTEGRINS; ION CHANNELS; NADPH OXIDASE; OXIDATIVE STRESS; PEPTIDE HYDROLASES; SIGNAL TRANSDUCTION; WATER-ELECTROLYTE BALANCE;

EID: 55949126414     PISSN: 00435341     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10354-008-0593-0     Document Type: Conference Paper

References (20)

1. D Häussinger 1996 The role of cellular hydration in the regulation of cell function Biochem J 321 697 710
2. F Lang GL Busch M Ritter H Volkl S Waldegger E Gulbins 1998 Functional significance of cell volume regulatory mechanisms Physiol Rev 78 247 306
3. J Graf D Häussinger 1996 Ion transport in hepatocytes: mechanisms and correlation to cell volume, hormone actions and metabolism J Hepatol 24 53 77
4. D Häussinger C Hallbrucker N Saha F Lang W Gerok 1992 Cell volume is a major determinant of bile acid excretion Biochem J 288 681 689
5. D Häussinger R Kubitz R Reinehr JG Bode F Schliess 2004 Molecular aspects of medicine: from experimental to clinical hepatology Aspects Mol Med 25 221 360
6. Häussinger D, Sies H (eds). Osmosensing and Osmosignaling. Methods in Enzymology, vol. 428, 2007
7. D Häussinger AK Kurz M Wettstein D Graf S vom Dahl F Schliess 2003 Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis Gastroenterology 124 1476 1487
8. S vom Dahl F Schliess R Reissmann B Görg O Weiergräber M Kocalkova F Dombrowski D Häussinger 2003 Involvement of integrins in osmosensing and signaling toward autophagic proteolysis in rat liver J Biol Chem 278 27088 27095
9. F Schliess R Reissmann R Reinehr S vom Dahl D Häussinger 2004 Involvement of integrins and Src in insulin signaling towards autophagic proteolysis in rat liver J Biol Chem 279 21294 21301
10. DE Ingber 1997 Tensegrity: the architectural basis of cellular mechanotransduction Annu Rev Physiol 59 575 599
11. M Schmitt R Kubitz S Lizun M Wettstein 2001 Regulation of the dynamic localization of the Bsep gene encoded bile salt export pump by anisoosmolarity Hepatology 33 509 518
12. +/taurocholate cotransport polypeptide is mediated via the phosphoinositide 3-kinase signaling pathway J Biol Chem 275 29754 29760
13. U Krause MH Rider L Hue 1996 Protein kinase signalling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes J Biol Chem 271 16668 16673
14. PR Bratusch-Marrain RA DeFronzo 1983 Impairment of insulin-mediated glucose metabolism by hyperosmolality in man Diabetes 32 1028 1034
15. M Komjati G Kastner W Waldhäusl PR Bratusch-Marrain 1988 Detrimental effect of hyperosmolarity on insulin-stimulated glucose metabolism in adipose and muscle tissue in vitro Biochem Med Metab Biol 39 312 318
16. M Komjati W Kastner W Waldhäusl PR Bratusch-Marrain 1989 Effect of hyperosmolality on basal and hormone-stimulated hepatic glucose metabolism in vitro Eur J Clin Invest 19 128 134
17. R Reinehr S Becker J Braun A Eberle S Grether-Beck D Häussinger 2006 Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis J Biol Chem 281 23150 23166
18. R Reinehr F Schliess D Haussinger 2003 Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation FASEB J 17 731 733
19. D Häussinger 2006 Low grade cerebral edema and the pathogenesis of hepatic encephalopathy in cirrhosis Hepatology 43 1187 1190
20. D Häussinger E Roth F Lang W Gerok 1993 The cellular hydratation state: a major determinant for protein catabolism in health and disease Lancet 341 1330 1332