Pretreatment with bone morphogenetic protein-7 (BMP-7) mimics ischemia preconditioning following intestinal ischemia/reperfusion injury in the intestine and liver

Shock

Volumn 30, Issue 5, 2008, Pages 532-536

  Radhakrishnan, Ravi S ^a   Radhakrishnan, Geetha L ^a   Radhakrishnan, Hari R ^a   Xue, Hasen ^a   Adams, Sasha D ^a   Moore Olufemi, Stacey D ^a   Harting, Matthew T ^a   Cox Jr , Charles S ^a,b   Kone, Bruce C ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

BMP 7; Ileus; Intestinal transit; Ischemia reperfusion

Indexed keywords

ASPARTATE AMINOTRANSFERASE; INTERLEUKIN 6; MYELOPEROXIDASE; RECOMBINANT OSTEOGENIC PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; HISTOPATHOLOGY; ILEUS; INTESTINE ISCHEMIA; INTESTINE TRANSIT TIME; ISCHEMIC PRECONDITIONING; LIVER INJURY; MALE; MICROARRAY ANALYSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; RAT; REPERFUSION INJURY; SUPERIOR MESENTERIC ARTERY OBSTRUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEIN 7; GASTROINTESTINAL TRANSIT; INTESTINES; ISCHEMIC PRECONDITIONING; LIVER; MALE; PEROXIDASE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 55949125930     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31816f20f1     Document Type: Article

References (33)

1. Bauer AJ, Schwarz NT, Moore BA, Turler A, Kalff JC: Ileus in critical illness: mechanisms and management. Curr Opin Crit Care 8:152-157, 2002.
2. Hassoun HT, Kone BC, Mercer DW, Moody FG, Weisbrodt NW, Moore FA: Post-injury multiple organ failure: the role of the gut. Shock 15:1-10, 2001.
3. Miedema BW, Schillie S, Simmons JW, Burgess SV, Liem T, Silver D: Small bowel motility and transit after aortic surgery. J Vasc Surg 36:19-24, 2002.
4. Moore-Olufemi SD, Kozar RA, Moore FA, Sato N, Hassoun HT, Cox CS Jr, Kone BC: Ischemic preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury. Shock 23:258-263, 2005.
5. Moore FA, Cocanour CS, McKinley BA, Kozar RA, DeSoignie RC, Von-Maszewski ME, Weisbrodt NW: Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition. J Trauma 51:1075-1082, 2001.
6. Choi SA, Kim EH, Lee JY, Nam HS, Kim SH, Kim GW, Lee BI, Heo JH: Preconditioning with chronic cerebral hypoperfusion reduces a focal cerebral ischemic injury and increases apurinic/apyrimidinic endonuclease/redox factor-1 and matrix metalloproteinase-2 expression. Curr Neurovasc Res 4:89-97, 2007.
7. Joo JD, Kim M, D'Agati VD, Lee HT: Ischemic preconditioning provides both acute and delayed protection against renal ischemia and reperfusion injury in mice. J Am Soc Nephrol 17:3115-3123, 2006.
8. Murry CE, Jennings RB, Reimer KA: Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124-1136, 1986.
9. Moore-Olufemi SD, Olufemi SE, Sato N, Kozar R, Moore FA, Radhakrishnan RS, Cox CS Jr, Kone BC: Transcriptional profiling of ischemic preconditioning (IPC) in rat intestine following ischemia/reperfusion injury. J Am Coll Surg 203:45, 2006.
10. Sampath TK, Reddi AH: Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation. Proc Natl Acad Sci U S A 78:7599-7603, 1981.
11. Urist MR: Bone: formation by autoinduction. Science 150:893-899, 1965.
12. Fiocchi C: TGF-beta/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammation. J Clin Invest 108:523-526, 2001.
13. Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP: SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway. Proc Natl Acad Sci U S A 98:9719-9723, 2001.
14. Simon M, Maresh JG, Harris SE, Hernandez JD, Arar M, Olson MS, Abboud HE: Expression of bone morphogenetic protein-7 mRNA in normal and ischemic adult rat kidney. Am J Physiol 276:F382-F389, 1999.
15. Vukicevic S, Basic V, Rogic D, Basic N, Shih MS, Shepard A, Jin D, Dattatreyamurty B, Jones W, Dorai H, et al.: Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat. J Clin Invest 102:202-214, 1998.
16. Maric I, Poljak L, Zoricic S, Bobinac D, Bosukonda D, Sampath KT, Vukicevic S: Bone morphogenetic protein-7 reduces the severity of colon tissue damage and accelerates the healing of inflammatory bowel disease in rats. J Cell Physiol 196:258-264, 2003.
17. Hassoun HT, Kozar RA, Kone BC, Safi HJ, Moore FA: Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric ischemia/reperfusion. Surgery 132:369-376, 2002.
18. Hassoun HT, Weisbrodt NW, Mercer DW, Kozar RA, Moody FG, Moore FA: Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults. J Surg Res 97:150-154, 2001.
19. Hassoun HT, Zou L, Moore FA, Kozar RA, Weisbrodt NW, Kone BC: Alpha-melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol 282:G1059-G1068, 2002.
20. Giannella E, Mochmann HC, Levi R: Ischemic preconditioning prevents the impairment of hypoxic coronary vasodilatation caused by ischemia/reperfusion: role of adenosine A1/A3 and bradykinin B2 receptor activation. Circ Res 81:415-422, 1997.
21. Sandhu R, Diaz RJ, Mao GD, Wilson GJ: Ischemic preconditioning: differences in protection and susceptibility to blockade with single-cycle versus multicycle transient ischemia. Circulation 96:984-995, 1997.
22. Xuan YT, Guo Y, Han H, Zhu Y, Bolli R: An essential role of the JAK-STAT pathway in ischemic preconditioning. Proc Natl Acad Sci U S A 98:9050-9055, 2001.
23. Callister WD: Materials Science and Engineering: An Introduction. New York: Wiley, 1994.
24. Chiu CJ, McArdle AH, Brown R, Scott HJ, Gurd FN: Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 101:478-483, 1970.
25. Liu TH, Robinson EK, Helmer KS, West SD, Castaneda AA, Chang L, Mercer DW: Does upregulation of inducible nitric oxide synthase play a role in hepatic injury? Shock 18:549-554, 2002.
26. Moore FA, Feliciano DV, Andrassy RJ, McArdle AH, Booth FV, Morgenstein-Wagner TB, Kellum JM Jr, Welling RE, Moore EE: Early enteral feeding, compared with parenteral, reduces postoperative septic complications. The results of a meta-analysis. Ann Surg 216:172-183, 1992.
27. Attuwaybi B, Kozar RA, Gates KS, Moore-Olufemi S, Sato N, Weisbrodt NW, Moore FA: Hypertonic saline prevents inflammation, injury, and impaired intestinal transit after gut ischemia/reperfusion by inducing heme oxygenase 1 enzyme. J Trauma 56:749-758, 2004. discussion 758-759.
28. Lund RJ, Davies MR, Hruska KA: Bone morphogenetic protein-7: an antifibrotic morphogenetic protein with therapeutic importance in renal disease. Curr Opin Nephrol Hypertens 11:31-36, 2002.
29. Yanagisawa M, Nakashima K, Takizawa T, Ochiai W, Arakawa H, Taga T: Signaling crosstalk underlying synergistic induction of astrocyte differentiation by BMPs and IL-6 family of cytokines. FEBS Lett 489:139-143, 2001.
30. Radhakrishnan RS, Radhakrishnan HR, Xue H, Moore-Olufemi SD, Mathur AB, Weisbrodt NW, Moore FA, Allen SJ, Laine GA, Cox CS Jr: Hypertonic saline reverses stiffness in a Sprague-Dawley rat model of acute intestinal edema, leading to improved intestinal function. Crit Care Med 35:538-543, 2007.
31. Radhakrishnan RS, Xue H, Moore-Olufemi SD, Weisbrodt NW, Moore FA, Allen SJ, Laine GA, Cox CS Jr: Hypertonic saline resuscitation prevents hydrostatically induced intestinal edema and ileus. Crit Care Med 34:1713-1718, 2006.
32. Radhakrishnan RS, Xue H, Weisbrodt N, Moore FA, Allen SJ, Laine GA, Cox CS Jr: Resuscitation-induced intestinal edema decreases the stiffness and residual stress of the intestine. Shock 24:165-170, 2005.
33. Uray KS, Laine GA, Xue H, Allen SJ, Cox CS Jr: Edema-induced intestinal dysfunction is mediated by STAT3 activation. Shock 28:239-244, 2007.