Synthesis of ethyl-(3R,5S)-dihydroxy-6-benzyloxyhexanoates via diastereo- and enantioselective microbial reduction: Cloning and expression of ketoreductase III from Acinetobacter sp. SC 13874

Enzyme and Microbial Technology

Volumn 43, Issue 7, 2008, Pages 544-549

  Goldberg, Steven ^a   Guo, Zhiwei ^a   Chen, Steve ^a   Goswami, Animesh ^a   Patel, Ramesh N ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Biocatalysis; Cloning and expression; Enantioselective diastereoselective reduction; Ketoreductase

Indexed keywords

CLONING; ESCHERICHIA COLI; ESTERIFICATION; GENE ENCODING; GENETIC ENGINEERING; ORGANIC COMPOUNDS; WATER POLLUTION;

ACINETOBACTER SP; BIOCATALYSIS; CLONING AND EXPRESSION; CLONING AND EXPRESSIONS; DIASTEREOMERIC EXCESSES; DIASTEREOSELECTIVE REDUCTIONS; ENANTIOMERIC EXCESSES; ENANTIOSELECTIVE; ENANTIOSELECTIVE DIASTEREOSELECTIVE REDUCTION; KETOREDUCTASE; MICROBIAL REDUCTIONS; RECOMBINANT E. COLI; SYNTHESIS OF;

ESTERS;

BACTERIAL ENZYME; KETOREDUCTASE 3; UNCLASSIFIED DRUG;

ACINETOBACTER; ARTICLE; BACTERIAL STRAIN; CATALYSIS; CLONING; DIASTEREOISOMER; ENANTIOSELECTIVITY; ENZYME ASSAY; NONHUMAN; PROTEIN EXPRESSION; REDUCTION;

ACINETOBACTER SP.; ESCHERICHIA COLI;

EID: 55949108367     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2008.07.005     Document Type: Article

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