메뉴 건너뛰기




Volumn 25, Issue 6, 2008, Pages 710-717

In vitro investigations for the QSAR mechanism of lymphocytes apoptosis induced by substituted aromatic toxicants

Author keywords

Apoptosis; Cytotoxicity; ELUMO; QSAR; ROS

Indexed keywords

CARASSIUS AURATUS;

EID: 55949093989     PISSN: 10504648     EISSN: 10959947     Source Type: Journal    
DOI: 10.1016/j.fsi.2008.02.008     Document Type: Article
Times cited : (15)

References (42)
  • 3
    • 18144404281 scopus 로고    scopus 로고
    • Comparing measured and predicted PCB concentrations in Arctic seawater and marine biota
    • Borga K., and Di Gardo A. Comparing measured and predicted PCB concentrations in Arctic seawater and marine biota. Science of the Total Environment 342 (2005) 281-300
    • (2005) Science of the Total Environment , vol.342 , pp. 281-300
    • Borga, K.1    Di Gardo, A.2
  • 4
    • 18244393991 scopus 로고    scopus 로고
    • Selected chlorobornanes, polychlorinated naphthalenes and brominated flame retardants in Bjornoya (Bear Island) freshwater biota
    • Evenset A., Christensen G.N., and Kallenborn R. Selected chlorobornanes, polychlorinated naphthalenes and brominated flame retardants in Bjornoya (Bear Island) freshwater biota. Environmental Pollution 136 (2005) 419-430
    • (2005) Environmental Pollution , vol.136 , pp. 419-430
    • Evenset, A.1    Christensen, G.N.2    Kallenborn, R.3
  • 5
    • 22044454459 scopus 로고    scopus 로고
    • Bioaccumulation and the effects of organochlorine pesticides, PAH and heavy metals in the eel (Anguilla anguilla) at the Camargue Nature Reserve, France
    • Oliveira Ribeiro C.A., Vollaire Y., Sanchez-Chardi A., and Roche H. Bioaccumulation and the effects of organochlorine pesticides, PAH and heavy metals in the eel (Anguilla anguilla) at the Camargue Nature Reserve, France. Aquatic Toxicology 74 (2005) 53-69
    • (2005) Aquatic Toxicology , vol.74 , pp. 53-69
    • Oliveira Ribeiro, C.A.1    Vollaire, Y.2    Sanchez-Chardi, A.3    Roche, H.4
  • 6
    • 17444425294 scopus 로고    scopus 로고
    • Aqueous exposure to Aroclor 1254 modulates the mitogenic response of Atlantic salmon anterior kidney T-cells: indications of short- and long-term immunomodulation
    • Iwanowica L.R., Lerner D., Blazer V.S., and McCorminck S.D. Aqueous exposure to Aroclor 1254 modulates the mitogenic response of Atlantic salmon anterior kidney T-cells: indications of short- and long-term immunomodulation. Aquatic Toxicology 72 (2005) 305-314
    • (2005) Aquatic Toxicology , vol.72 , pp. 305-314
    • Iwanowica, L.R.1    Lerner, D.2    Blazer, V.S.3    McCorminck, S.D.4
  • 7
    • 33644779627 scopus 로고    scopus 로고
    • The relationship between noncoplanar PCB-induced immunotoxicity and hepatic CYP1A induction in a fish model
    • Duffy J., and Zelikoff J. The relationship between noncoplanar PCB-induced immunotoxicity and hepatic CYP1A induction in a fish model. Journal of Immunotoxicology 3 (2006) 39-47
    • (2006) Journal of Immunotoxicology , vol.3 , pp. 39-47
    • Duffy, J.1    Zelikoff, J.2
  • 8
    • 14744274651 scopus 로고    scopus 로고
    • p,p′-DDE depresses the immune competence of chinook salmon (Oncorhynchus tshawytscha) leukocytes
    • Misumi I., Vella A.T., Leong J.C., Nakanishi T., and Schreck C.B. p,p′-DDE depresses the immune competence of chinook salmon (Oncorhynchus tshawytscha) leukocytes. Fish and Shellfish Immunology 19 (2005) 97-114
    • (2005) Fish and Shellfish Immunology , vol.19 , pp. 97-114
    • Misumi, I.1    Vella, A.T.2    Leong, J.C.3    Nakanishi, T.4    Schreck, C.B.5
  • 10
    • 0031993509 scopus 로고    scopus 로고
    • Fish thymocyte viability, apoptosis and necrosis: in-vitro effects of organochlorine contaminants
    • Sweet L.I., Passion-Reader D.R., Meier P.G., and Omann G.M. Fish thymocyte viability, apoptosis and necrosis: in-vitro effects of organochlorine contaminants. Fish and Shellfish Immunology 8 (1998) 77-90
    • (1998) Fish and Shellfish Immunology , vol.8 , pp. 77-90
    • Sweet, L.I.1    Passion-Reader, D.R.2    Meier, P.G.3    Omann, G.M.4
  • 13
    • 0032703244 scopus 로고    scopus 로고
    • Assessment of apoptosis in xenobiotic-induced immunotoxicity
    • Pallardy M., Biola A., Lebrec H., and Breard J. Assessment of apoptosis in xenobiotic-induced immunotoxicity. Methods 19 (1999) 36-47
    • (1999) Methods , vol.19 , pp. 36-47
    • Pallardy, M.1    Biola, A.2    Lebrec, H.3    Breard, J.4
  • 15
    • 33846881820 scopus 로고    scopus 로고
    • Structure-activity relationships for halobenzene induced cytotoxicity in rat and human hepatocytes
    • Chan K., Jensen N.S., Silber P.A., and O'Brien P.J. Structure-activity relationships for halobenzene induced cytotoxicity in rat and human hepatocytes. Chemico-Biological Interactions 165 (2007) 165-174
    • (2007) Chemico-Biological Interactions , vol.165 , pp. 165-174
    • Chan, K.1    Jensen, N.S.2    Silber, P.A.3    O'Brien, P.J.4
  • 17
    • 0033917852 scopus 로고    scopus 로고
    • Quantitative structure-activity relationship of flavonoids for inhibition of heterocyclic amine mutagenicity
    • Hatch F.T., Lightstone F.C., and Colvin M.E. Quantitative structure-activity relationship of flavonoids for inhibition of heterocyclic amine mutagenicity. Environmental and Molecular Mutagenesis 35 (2000) 279-299
    • (2000) Environmental and Molecular Mutagenesis , vol.35 , pp. 279-299
    • Hatch, F.T.1    Lightstone, F.C.2    Colvin, M.E.3
  • 18
    • 33947134892 scopus 로고    scopus 로고
    • Estimation of gas-phase reaction rate constants of alkylnaphthalenes with chlorine, hydroxyl and nitrate radicals
    • Long X.X., and Niu J.F. Estimation of gas-phase reaction rate constants of alkylnaphthalenes with chlorine, hydroxyl and nitrate radicals. Chemosphere 67 (2007) 2028-2034
    • (2007) Chemosphere , vol.67 , pp. 2028-2034
    • Long, X.X.1    Niu, J.F.2
  • 19
    • 0029160177 scopus 로고
    • Quantitative structure-activity relationships and ecological risk assessment: an overview of predictive aquatic toxicology research
    • Bradbury S.P. Quantitative structure-activity relationships and ecological risk assessment: an overview of predictive aquatic toxicology research. Toxicology Letters 79 (1995) 229-237
    • (1995) Toxicology Letters , vol.79 , pp. 229-237
    • Bradbury, S.P.1
  • 20
    • 0030771347 scopus 로고    scopus 로고
    • QSAR and 3D QSAR in drug design. Part 1: methodology
    • Kubinyi H. QSAR and 3D QSAR in drug design. Part 1: methodology. Drug Discovery Today 2 (1997) 457-467
    • (1997) Drug Discovery Today , vol.2 , pp. 457-467
    • Kubinyi, H.1
  • 21
    • 34250825348 scopus 로고    scopus 로고
    • Mode of action-based local QSAR modeling for the prediction of acute toxicity in the fathead minnow
    • Yuan H., Wang Y.Y., and Cheng Y.Y. Mode of action-based local QSAR modeling for the prediction of acute toxicity in the fathead minnow. Journal of Molecular Graphics and Modelling 26 (2007) 327-335
    • (2007) Journal of Molecular Graphics and Modelling , vol.26 , pp. 327-335
    • Yuan, H.1    Wang, Y.Y.2    Cheng, Y.Y.3
  • 22
    • 0242401969 scopus 로고    scopus 로고
    • QSAR modeling of genotoxicity on non-congeneric sets of organic compounds
    • Maran U., and Slid S. QSAR modeling of genotoxicity on non-congeneric sets of organic compounds. Artificial Intelligence Review 20 (2003) 13-38
    • (2003) Artificial Intelligence Review , vol.20 , pp. 13-38
    • Maran, U.1    Slid, S.2
  • 23
    • 36148935631 scopus 로고    scopus 로고
    • Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models
    • Contrera J.F., Kruhlak N.L., Matthews E.J., and Benz R.D. Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models. Regulatory Toxicology and Pharmacology 49 (2007) 172-182
    • (2007) Regulatory Toxicology and Pharmacology , vol.49 , pp. 172-182
    • Contrera, J.F.1    Kruhlak, N.L.2    Matthews, E.J.3    Benz, R.D.4
  • 24
    • 33847059296 scopus 로고    scopus 로고
    • Approaches for externally validated QSAR modelling of nitrated polycyclic aromatic hydrocarbon mutagenicity
    • Gramatica P., Lilutti P., and Papa E. Approaches for externally validated QSAR modelling of nitrated polycyclic aromatic hydrocarbon mutagenicity. SAR and QSAR in Environmental Research 18 (2007) 169-178
    • (2007) SAR and QSAR in Environmental Research , vol.18 , pp. 169-178
    • Gramatica, P.1    Lilutti, P.2    Papa, E.3
  • 25
    • 0344806276 scopus 로고    scopus 로고
    • Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationships
    • Sergediene E., Jonsson K., Szymusiak H., Tyrakowska B., Rietjens I.M.C.M., and Cenas N. Prooxidant toxicity of polyphenolic antioxidants to HL-60 cells: description of quantitative structure-activity relationships. FEBS Letters 462 (1999) 392-396
    • (1999) FEBS Letters , vol.462 , pp. 392-396
    • Sergediene, E.1    Jonsson, K.2    Szymusiak, H.3    Tyrakowska, B.4    Rietjens, I.M.C.M.5    Cenas, N.6
  • 26
    • 35348816323 scopus 로고    scopus 로고
    • A novel QSAR model for prediction of apoptosis-inducing activity of 4-aryl-4-H-chromenes based on support vector machine
    • Fatemi M.H., and Gharaghani S. A novel QSAR model for prediction of apoptosis-inducing activity of 4-aryl-4-H-chromenes based on support vector machine. Bioorganic and Medicinal Chemistry 15 (2007) 7746-7754
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , pp. 7746-7754
    • Fatemi, M.H.1    Gharaghani, S.2
  • 27
    • 28544441042 scopus 로고    scopus 로고
    • Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study
    • Selassie C.D., Kapur S., Verma R.P., and Rosario M. Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study. Journal of Medicinal Chemistry 48 (2005) 7234-7242
    • (2005) Journal of Medicinal Chemistry , vol.48 , pp. 7234-7242
    • Selassie, C.D.1    Kapur, S.2    Verma, R.P.3    Rosario, M.4
  • 30
    • 25144441808 scopus 로고    scopus 로고
    • Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions
    • Kemnitzer W., Kasibhatla S., Jiang S., Zhang H., Zhao J., Jia S., et al. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions. Bioorganic and Medicinal Chemistry Letters 15 (2005) 4745-4751
    • (2005) Bioorganic and Medicinal Chemistry Letters , vol.15 , pp. 4745-4751
    • Kemnitzer, W.1    Kasibhatla, S.2    Jiang, S.3    Zhang, H.4    Zhao, J.5    Jia, S.6
  • 32
    • 35448962596 scopus 로고    scopus 로고
    • Immunophenotyping of hematological malignancies by laser scanning cytometry
    • Clatch R.J. Immunophenotyping of hematological malignancies by laser scanning cytometry. Methods in Cell Biology 64 (2001) 313-317
    • (2001) Methods in Cell Biology , vol.64 , pp. 313-317
    • Clatch, R.J.1
  • 33
    • 0032743887 scopus 로고    scopus 로고
    • Carbonic anhydrase inhibitors - part 57: quantum chemical QSAR of a group of 1,3,4-thiadiazole- and 1,3,4-thiadiazoline disulfonamides with carbonic anhydrase inhibitory properties
    • Supuran C.T., and Clare B.W. Carbonic anhydrase inhibitors - part 57: quantum chemical QSAR of a group of 1,3,4-thiadiazole- and 1,3,4-thiadiazoline disulfonamides with carbonic anhydrase inhibitory properties. European Journal of Medicinal Chemistry 34 (1999) 41-50
    • (1999) European Journal of Medicinal Chemistry , vol.34 , pp. 41-50
    • Supuran, C.T.1    Clare, B.W.2
  • 34
    • 0031178854 scopus 로고    scopus 로고
    • Evaluation of a novel infrared range vibration-based descriptor (EVA) for QSAR studies. 1. General application
    • Turner D.B., Willett P., Ferguson A.M., and Heritage T. Evaluation of a novel infrared range vibration-based descriptor (EVA) for QSAR studies. 1. General application. Journal of Computer-Aided Molecular Design 11 (1997) 409-422
    • (1997) Journal of Computer-Aided Molecular Design , vol.11 , pp. 409-422
    • Turner, D.B.1    Willett, P.2    Ferguson, A.M.3    Heritage, T.4
  • 35
    • 0035987858 scopus 로고    scopus 로고
    • A QSAR model for predicting toxicity (LC50) to rainbow trout
    • Tao S., Xi X., Xu F., and Dawson R. A QSAR model for predicting toxicity (LC50) to rainbow trout. Water Research 36 (2002) 2926-2930
    • (2002) Water Research , vol.36 , pp. 2926-2930
    • Tao, S.1    Xi, X.2    Xu, F.3    Dawson, R.4
  • 37
    • 0028884744 scopus 로고
    • An analysis of protein-folding type prediction by seed-propagated sampling and jackknife test
    • Zhang C.T., and Chou K.C. An analysis of protein-folding type prediction by seed-propagated sampling and jackknife test. Journal of Protein Chemistry 14 (1995) 583-593
    • (1995) Journal of Protein Chemistry , vol.14 , pp. 583-593
    • Zhang, C.T.1    Chou, K.C.2
  • 38
    • 0034886230 scopus 로고    scopus 로고
    • Progressive study and robustness test of QSAR model based on quantum chemical parameters for predicting BCF of selected polychlorinated organic compounds (PCOCs)
    • Wei D., Zhang A., Wu C., Han S., and Wang L. Progressive study and robustness test of QSAR model based on quantum chemical parameters for predicting BCF of selected polychlorinated organic compounds (PCOCs). Chemosphere 44 (2001) 1421-1428
    • (2001) Chemosphere , vol.44 , pp. 1421-1428
    • Wei, D.1    Zhang, A.2    Wu, C.3    Han, S.4    Wang, L.5
  • 39
    • 12844276639 scopus 로고    scopus 로고
    • QSAR studies on some thiophene analogs as anti-inflammatory agents: enhancement of activity by electronic parameters and its utilization for chemical lead optimization
    • Pillai A.D., Rani S., Rathod P., Xavier F.P., Vasu K.K., Padh H., et al. QSAR studies on some thiophene analogs as anti-inflammatory agents: enhancement of activity by electronic parameters and its utilization for chemical lead optimization. Bioorganic and Medicinal Chemistry 13 (2005) 1275-1283
    • (2005) Bioorganic and Medicinal Chemistry , vol.13 , pp. 1275-1283
    • Pillai, A.D.1    Rani, S.2    Rathod, P.3    Xavier, F.P.4    Vasu, K.K.5    Padh, H.6
  • 40
    • 53149137110 scopus 로고    scopus 로고
    • Liao SY, Chen JC, Qian L, Shen Y, Zheng KC. QSAR, action mechanism and molecular design of flavone and isoflavone derivatives with cytotoxicity against HeLa. European Journal of Medicinal Chemistry. doi: 10.10 16/j.ejmech.2007.10.033.
    • Liao SY, Chen JC, Qian L, Shen Y, Zheng KC. QSAR, action mechanism and molecular design of flavone and isoflavone derivatives with cytotoxicity against HeLa. European Journal of Medicinal Chemistry. doi: 10.10 16/j.ejmech.2007.10.033.
  • 42
    • 55949101841 scopus 로고    scopus 로고
    • Kuznetsov AV, Doblander C, Tina G, Schneider M, Janakiraman M, Troppmair J. C-Raf protects against ROS-induced apoptosis. .
    • Kuznetsov AV, Doblander C, Tina G, Schneider M, Janakiraman M, Troppmair J. C-Raf protects against ROS-induced apoptosis. .


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.