Pharmacological intervention of tiferron and propolis to alleviate beryllium-induced hepatorenal toxicity

Fundamental and Clinical Pharmacology

Volumn 22, Issue 4, 2008, Pages 403-415

  Nirala, Satendra Kumar ^a   Bhadauria, Monika ^a   Shukla, Sangeeta ^a   Agrawal, Om Prakash ^a   Mathur, Asha ^b   Li, Pei Qiang ^c   Mathur, Ramesh ^a  

^a JIWAJI UNIVERSITY   (India)

^b KRG College   (India)

^c LANZHOU UNIVERSITY   (China)

Author keywords

Beryllium toxicity; Pharmacological intervention; Propolis; Tiferron; Ultramorphology

Indexed keywords

ACID PHOSPHATASE; ADENOSINE TRIPHOSPHATASE; ALKALINE PHOSPHATASE; BERYLLIUM; BILIRUBIN; CREATININE; CYTOCHROME P450; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE 6 PHOSPHATASE; LACTATE DEHYDROGENASE; PROPOLIS; SUCCINATE DEHYDROGENASE; TIRON; UREA; ANTIOXIDANT; BENZENESULFONIC ACID DERIVATIVE; BERYLLIUM NITRATE; CHELATING AGENT; NITRATE; SODIUM 4,5 DIHYDROXY 1,3 BENZENE DISULFONATE; SODIUM-4,5-DIHYDROXY-1,3-BENZENE DISULFONATE;

ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD LEVEL; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE SEVERITY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEPATORENAL TOXICITY; HISTOPATHOLOGY; KIDNEY FUNCTION TEST; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LIVER FUNCTION TEST; LIVER LEVEL; LIVER MICROSOME; LIVER TOXICITY; MICROSCOPY; MONOTHERAPY; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT DURATION; UREA BLOOD LEVEL; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG COMBINATION; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; HEPATORENAL SYNDROME; KIDNEY; LIVER; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; BENZENESULFONATES; BERYLLIUM; CHELATING AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FEMALE; HEPATORENAL SYNDROME; KIDNEY; KIDNEY FUNCTION TESTS; LIPID PEROXIDATION; LIVER; LIVER FUNCTION TESTS; NITRATES; PROPOLIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 55949087618     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2008.00603.x     Document Type: Article

References (56)

1. Stonehouse A.J., Zenczak S. Properties, production process and application, in: Rossman M.D., Preuses O.P., Powers M.B. (Eds), Beryllium: biomedical and environmental aspects, Williams and Wilkins, Baltimore, 1991, pp. 276-655.
2. Kolanz M. Introduction to beryllium: uses, regulatory history and disease. Appl. Occup. Environ. Hyg. J. (2001) 16 559-567.
3. Weston A., Snyder J., McCanlies E.C., Schuler C.R., Kreiss K., Demchuk E. Immunogenetic factors in beryllium sensitization and chronic beryllium disease. Mutat. Res. (2005) 592 68-78.
4. USEPA (U.S. Environmental Protection Agency) Health effects assessment for beryllium and compounds. Prepared for Office of Solid Waste and Emergency Response by Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, USEPA, Washington, DC, ECAO-CIN-H113, 1987.
5. Sawicka-Kapusta K., Jakrzewska M., Orzechowski T. Seasonal changes of metal concentration in small mammal's populations from different contaminated areas, in: Ketrup A., Schramm K.W. (Eds), Proc. SACOTOX. X. Fifth Eur. Conf. Ecotoxicol. Environ. Safety, March 15-17, GSF-National Research Center, Neuherberg, Munich, Germany, 1999, pp. 15-17.
6. Appleton J., Lee K.M., Sawicka-Kapusta K., Damek M., Cook M. The heavy metal content of the teeth of the bank vole (Clethrio-nomys glareolus) as an exposure marker of environmental pollution in Poland. Environ. Pollut. (2000) 110 441-449.
7. Vorwold A.J., Reeves A.L., Urban E.C.J. Experimental beryllium toxicology, in: Stokinger H.E. (Ed.), Beryllium, its industrial hygiene aspects, Academic Press, New York, London, 1966, pp. 201-234.
8. WHO (World Health Organization) Environmental Health Criteria: 106 'Beryllium', International Programme on Chemical Safety, World Health Organization, Geneva, 1990.
9. Yokel R.A. Aluminum chelation: chemistry, clinical and experimental studies and the search for alternatives to desfer-rioxamine. J. Toxicol. Environ. Health (1994) 41 131-174.
10. Bosque M.A., Domingo J.L., Corbella J. Assesment of the developmental toxicity of deferoxamine in mice. Arch. Toxicol. (1995) 69 467-471.
11. Franchini M., Veneri D. Iron-chelation therapy: an update. Hematol. J. (2004) 5 287-292.
12. Sanchez D.J., Gomez M., Domingo J.L., Llobet J.M., Corbella J. Relative efficacy of chelating agents on excretion and tissue distribution of manganese in mice. J. Appl. Toxicol. (1995) 15 285-288.
13. Bosque M.A., Domingo J.L., Llobett J.M., Corbella J. Effectiveness of sodium-4,5-dihydroxy-1,3-benzene disulphonate (Tiron) in protecting against uranium induced developmental toxicity in mice. Toxicology (1993) 79 149-156.
14. Pocock G., Simons T.J. Effects of lead ions on events associated with exocytosis in isolated bovine adrenal medullary cells. J. Neurochem. (1987) 48 376-382.
15. Domingo J.L. Prevention by chelating agents of metal induced developmental toxicity. Reprod. Toxicol. (1995) 9 105-113.
16. Sharma P., Shah Z., Shukla S. Protective effect of Tiron (4,5-dihydroxybenzene-1,3-disulphonic acid disodium salt) against beryllium induced maternal and fetal toxicity in rats. Arch. Toxicol. (2002) 76 442-448.
17. 3DTPA and tiron along with α-tocopherol against beryllium induced biochemical alterations in rats. Indian J. Exp. Biol. (2004) 42 570-574.
18. Bryan R.M. Jr, Steenberg M.L., Marrelli S.P. Role of endothelium in shear stress-induced constrictions in rat middle cerebral artery. Stroke (2001) 32 1394-1400.
19. Simoes L.M.C., Gregorio L.E., Da Silva Filho A.A. et al. Effect of Brazilian propolis on the production of reactive oxygen species by stimulated neutrophils. J. Ethnopharmacol. (2004) 94 59-65.
20. Pascual C., Gonzalez R., Torricella R. Scavenging action of propolis extract against oxygen radicals. J. Ethnopharmacol. (1994) 41 9-13.
21. Bhadauria M., Nirala S.K., Shukla S. Propolis protects CYP2E1 enzymatic activities and oxidative stress induced by carbon tetrachloride. Mol. Cell. Biochem. (2007) 302 215-224.
22. Koo H., Gomes B.P., Rosalen P.L., Ambrosano G.M., Park Y.K., Cury J.A. In vitro antimicrobial activity of propolis and Arnica montanna against oral pathogens. Arch. Oral Biol. (2000) 45 141-148.
23. Kujumgiev A., Tsretkova I., Serkedjieva Yu., Bankova V., Christov R., Popov S. Antibacterial, antifungal and antiviral activities of propolis of different geographic origin. J. Ethnopharmacol. (1999) 64 235-240.
24. Nirala S.K., Bhadauria M., Mathur R., Mathur A. Influence of α-tocopherol, propolis and piperine on therapeutic potential of tiferron against beryllium induced toxic manifestations. J. Appl. Toxicol. (2007) 28 44-54.
25. Nirala S.K., Bhadauria M., Mathur R., Mathur A. Amelioration of beryllium induced alterations in hepatorenal biochemistry and ultramorphology by co-administration of tiferron and adjuvants. J. Biomed. Sci. (2007) 14 331-345.
26. Bokowski D.L. Rapid determination of beryllium by direct reading spectrophotometer. Am. Indust. Hyg. Assoc. J. (1968) 29 474-481.
27. Schenkman J.B., Cinti D.L. Preparation of microsomes with calcium. Methods Enzymol. (1978) 52 83-89.
28. Kato R., Gillette J.R. Effect of starvation on NADPH-dependent enzymes in liver microsomes of male and female rats. J. Pharmacol. Exp. Ther. (1965) 150 279-284.
29. Cochin J., Axelrod J. Biochemical pharmacological changes in the rats following chronic administration of morphine. J. Pharmacol. Exp. Ther. (1959) 125 105-110.
30. Sharma S.K., Krishna Murti C.R. Production of lipidperoxides of brain. J. Neurochem. (1968) 15 147-149.
31. Lowry O.H., Rosenbrough N.J., Farr A.L., Randall R.J. Protein measurement with Folin's phenol reagent. J. Biol. Chem. (1951) 193 265-275.
32. Wroblewski F., La Due J.S. Colorimetric method for LDH, in: Wootton I.D.P. (Ed.), Microanalysis in medical biochemistry, 4th edn, J and A Churchill Ltd, Gloucester Place, London, 1955, pp. 15-118.
33. Fiske C.H., Subbarow Y. The colorimetric determination of phosphatase. J. Biol. Chem. (1925) 66 375-400.
34. Seth P.K., Tangri K.K. Biochemical effects of newer salicylic acid congeners. J. Pharm. Pharmacol. (1966) 18 831-833.
35. Baginski E.S., Foa P.P., Zak B. Glucose-6-phosphate, in: Bergmeyer H.U. (Ed.), Methods in enzymatic analysis, 2nd edn, Verlag Chemie Weinheiem, Academy Press Inc., New York, 1974, pp. 876-880.
36. Slater E.C., Bonner W.D. The effect of fluoride on the succinic oxidase system. Biochem. J. (1952) 82 185-191.
37. Hayat A., Arif M. Principles and techniques of electron microscopy: biological application, Van Nostrard Reinhold Company, New York, 1970.
38. Snedecor G.W., Cochran W.G. Statistical method, 8th edn, Iowa State University Press, Ames, 1994, 217-236.
39. Sharma P., Johri S., Shukla S. Beryllium induced toxicity and its prevention by treatment with chelating agents. J. Appl. Toxicol. (2000) 20 313-318.
40. Pietta P., Simonetti P., Gordana C., Brusamolino A., Morazzoni P., Bombardelli E. Relationship between rate and extent of cathechin absorption and plasma antioxidant status. Biochem. Mol. Biol. Int. (1998) 46 895-903.
41. Goepter A.R., Scheerens H., Vermeulen N.P.E. Oxygen and xenobiotics reductase activities in cytochrome P450. Clin. Rev. Toxicol. (1995) 25 59-84.
42. Krishna C.M., Liebmann J.E., Kaufman D. et al. The catecholic metal sequestering agent 1,2-dihydroxybenzene-3,5-disulfonate confers protection against oxidative cell damage. Arch. Biochem. Biophys. (1992) 294 98-106.
43. Zimmerman H.J. Hepatic failure, in: Gall E.A., Mostofi F.K. (Eds), The liver, Williams and Wilkins Co., Baltimore, 1973, pp. 384-405.
44. Edmondson H.A., Peters R.L. Liver, in: Kissane J.H. (Ed.), Andersons pathology, Vol. 2, CV Mosby Co., Torento, St Louis, 1985, pp. 1097-1101.
45. Atessahin A., Karahan I., Yilmaz S., Ceribasi A.O., Princci I. The effect of manganese chloride on gentamicin induced nephro-toxicity in rats. Pharmacol. Res. (2003) 48 637-642.
46. Meister A., Tate S.S. Glutathione and related gamma-glutamyl compounds: biosynthesis and utilization. Annu. Rev. Biochem. (1976) 45 559-604.
47. Novikoff A.B. The cell, in: Brachet J., Mirsky A.E. (Eds), Lysosomes and related particles, Vol. 2, Academic Press, New York, 1961, pp. 423-488.
48. Reeves A.L. Beryllium, in: Friberg L., Nordberg G.F., Vounk V.B., (Eds), Handbook of the toxicity of the metals, specific metals, Vol. 2, Elsevier Publications, New York, 1986, pp. 95-116.
49. Verity M.A., Reith A. Effect of mercurial compounds on the structure-linked latency of lysosomal hydrolases. Biochem. J. (1967) 105 685-690.
50. Boukhalfa H., Lewis J.G., Crumbliss A.L. Beryllium (II) binding to ATP and ADP: potentiometric determination of thermo- dynamic constants and implications for in vivo toxicity. Biometals (2004) 17 105-109.
51. Pickering C.E., Pickering R.G. Alkaline phosphatase activity of the mouse. Comp. Biochem. Physiol. Part C (1984) 79 417-424.
52. Du Bois K.P., Cochran K.W., Mazur M. Inhibition of phospha-tases by beryllium and antagonism of the inhibition by manganese. Science (1949) 110 420-422.
53. Thomas M., Aldridge W.N. The inhibition of enzymes by beryllium. Biochem. J. (1966) 98 94-99.
54. Mukhina S.T. Effect of magnesium on oxidative processes in rat liver and lung homogenates as a result of experimental beryllium intoxication. Gig. Tr. Proj. Zabol. (1967) 11 43-46 (in Russian).
55. Ortega A., Sanchez D.J., Domingo J.L., Llobet J.M., Corbella J. Development toxicity evaluation of tiron (sodium 4, 5-dihy-droxybenzene-1,3 disulfonate) in mice. Res. Commun. Chem. Pathol. Pharmacol. (1991) 73 97-106.
56. Burdock G.A. Review of the biological properties and toxicity of bee propolis. Food Chem. Toxicol. (1998) 36 347-368.