Tic-tac-toe does not provide lessons for appreciating the HLA-rheumatoid arthritis relationship: Comment on the editorial by Bridges et al

Arthritis and Rheumatism

Volumn 58, Issue 11, 2008, Pages 3635-

  Van Der Helm van Mil, A H M ^a   Huizinga, T W J ^a   De Vries, R R P ^a   Toes, R E M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN;

DISEASE ASSOCIATION; HLA SYSTEM; HUMAN; IMMUNOGENETICS; LETTER; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ARTHRITIS, RHEUMATOID; DISEASE SUSCEPTIBILITY; HLA ANTIGENS; HUMANS;

EID: 55849146261     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24033     Document Type: Letter

References (6)

1. Bridges SL Jr, Kelley JM, Hughes LB. The HLA-DRB1 shared epitope in Caucasians with rheumatoid arthritis: a lesson learned from tic-tac-toe [editorial]. Arthritis Rheum 2008;58:1211-5.
2. Svejgaard A, Ryder LP. HLA and disease associations: detecting the strongest association. Tissue Antigens 1994;43:18-27.
3. Van der Helm-van Mil AH, Huizinga TW, Schreuder GM, Breedveld FC, de Vries RR, Toes RE. An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility. Arthritis Rheum 2005;52:2637-44.
4. Feitsma AL, Worthington J, van der Helm-van Mil AH, Plant D, Thomson W, Ursum J, et al. Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development. Proc Natl Acad Sci U S A 2007;104:19966-70.
5. De Vries N, Tijssen H, van Riel PL, van de Putte LB. Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule. Arthritis Rheum 2002;46:921-8.
6. Reviron D, Perdriger A, Toussirot E, Wendling D, Balandraud N, Guis S, et al. Influence of shared epitope-negative HLA-DRB1 alleles on genetic susceptibility to rheumatoid arthritis. Arthritis Rheum 2001;44:535-40.